sgRNA Sequence Motifs Blocking Efficient CRISPR/Cas9-Mediated Gene Editing

por Graf, Robin, Li, Xun, Chu, Van Trung, Rajewsky, Klaus
Publicado 2019

Identification of LIN28B-bound mRNAs reveals features of target recognition and regulation

por Graf, Robin, Munschauer, Mathias, Mastrobuoni, Guido, Mayr, Florian, Heinemann, Udo, Kempa, Stefan, Rajewsky, Nikolaus, Landthaler, Markus
Publicado 2013

B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS

por Schmidt, Kristin, Sack, Ulrike, Graf, Robin, Winkler, Wiebke, Popp, Oliver, Mertins, Philipp, Sommermann, Thomas, Kocks, Christine, Rajewsky, Klaus
Publicado 2020

Efficient generation of Rosa26 knock-in mice using CRISPR/Cas9 in C57BL/6 zygotes

por Chu, Van Trung, Weber, Timm, Graf, Robin, Sommermann, Thomas, Petsch, Kerstin, Sack, Ulrike, Volchkov, Pavel, Rajewsky, Klaus, Kühn, Ralf
Publicado 2016

Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells

por Tran, Ngoc Tung, Sommermann, Thomas, Graf, Robin, Trombke, Janine, Pempe, Jenniffer, Petsch, Kerstin, Kühn, Ralf, Rajewsky, Klaus, Chu, Van Trung
Publicado 2019

CRISPR-Cas9-Mediated ELANE Mutation Correction in Hematopoietic Stem and Progenitor Cells to Treat Severe Congenital Neutropenia

por Tran, Ngoc Tung, Graf, Robin, Wulf-Goldenberg, Annika, Stecklum, Maria, Strauß, Gabriele, Kühn, Ralf, Kocks, Christine, Rajewsky, Klaus, Chu, Van Trung
Publicado 2020

Precise CRISPR-Cas–mediated gene repair with minimal off-target and unintended on-target mutations in human hematopoietic stem cells

por Tran, Ngoc Tung, Danner, Eric, Li, Xun, Graf, Robin, Lebedin, Mikhail, de la Rosa, Kathrin, Kühn, Ralf, Rajewsky, Klaus, Chu, Van Trung
Publicado 2022

PDGFA-associated protein 1 protects mature B lymphocytes from stress-induced cell death and promotes antibody gene diversification

por Delgado-Benito, Verónica, Berruezo-Llacuna, Maria, Altwasser, Robert, Winkler, Wiebke, Sundaravinayagam, Devakumar, Balasubramanian, Sandhya, Caganova, Marieta, Graf, Robin, Rahjouei, Ali, Henke, Marie-Thérèse, Driesner, Madlen, Keller, Lisa, Prigione, Alessandro, Janz, Martin, Akalin, Altuna, Di Virgilio, Michela
Publicado 2020