The application of transcriptional blood signatures to enhance our understanding of the host response to infection: the example of tuberculosis

por Blankley, Simon, Berry, Matthew Paul Reddoch, Graham, Christine M., Bloom, Chloe I., Lipman, Marc, O'Garra, Anne
Publicado 2014

Identification of the Key Differential Transcriptional Responses of Human Whole Blood Following TLR2 or TLR4 Ligation In-Vitro

por Blankley, Simon, Graham, Christine M., Howes, Ashleigh, Bloom, Chloe I., Berry, Matthew P. R., Chaussabel, Damien, Pascual, Virginia, Banchereau, Jacques, Lipman, Marc, O’Garra, Anne
Publicado 2014

Differential Production of Type I IFN Determines the Reciprocal Levels of IL-10 and Proinflammatory Cytokines Produced by C57BL/6 and BALB/c Macrophages

por Howes, Ashleigh, Taubert, Christina, Blankley, Simon, Spink, Natasha, Wu, Xuemei, Graham, Christine M., Zhao, Jiawen, Saraiva, Margarida, Ricciardi-Castagnoli, Paola, Bancroft, Gregory J., O’Garra, Anne
Publicado 2016

Analysis of Transcriptional Signatures in Response to Listeria monocytogenes Infection Reveals Temporal Changes That Result from Type I Interferon Signaling

por Pitt, Jonathan M., Blankley, Simon, Potempa, Krzysztof, Graham, Christine M., Moreira-Teixeira, Lucia, McNab, Finlay W., Howes, Ashleigh, Stavropoulos, Evangelos, Pascual, Virginia, Banchereau, Jacques, Chaussabel, Damien, O’Garra, Anne
Publicado 2016

Programmed death ligand 1 is over-expressed by neutrophils in the blood of patients with active tuberculosis

por McNab, Finlay W, Berry, Matthew P R, Graham, Christine M, Bloch, Susannah A A, Oni, Tolu, Wilkinson, Katalin A, Wilkinson, Robert J, Kon, Onn M, Banchereau, Jacques, Chaussabel, Damien, O'Garra, Anne
Publicado 2011

Progression of whole blood transcriptional signatures from interferon-induced to neutrophil-associated patterns in patients with severe influenza

por Dunning, Jake, Blankley, Simon, Hoang, Long T, Cox, Mike, Graham, Christine M, James, Philip L, Bloom, Chloe I, Chaussabel, Damien, Banchereau, Jacques, Brett, Stephen J., Moffatt, Miriam F, O’Garra, Anne, Openshaw, Peter JM
Publicado 2018

Blood transcriptomics reveal the evolution and resolution of the immune response in tuberculosis

por Tabone, Olivier, Verma, Raman, Singhania, Akul, Chakravarty, Probir, Branchett, William J., Graham, Christine M., Lee, Jo, Trang, Tran, Reynier, Frederic, Leissner, Philippe, Kaiser, Karine, Rodrigue, Marc, Woltmann, Gerrit, Haldar, Pranabashis, O’Garra, Anne
Publicado 2021

The Transcriptional Signature of Active Tuberculosis Reflects Symptom Status in Extra-Pulmonary and Pulmonary Tuberculosis

por Blankley, Simon, Graham, Christine M., Turner, Jacob, Berry, Matthew P. R., Bloom, Chloe I., Xu, Zhaohui, Pascual, Virginia, Banchereau, Jacques, Chaussabel, Damien, Breen, Ronan, Santis, George, Blankenship, Derek M., Lipman, Marc, O’Garra, Anne
Publicado 2016

A modular transcriptional signature identifies phenotypic heterogeneity of human tuberculosis infection

por Singhania, Akul, Verma, Raman, Graham, Christine M., Lee, Jo, Tran, Trang, Richardson, Matthew, Lecine, Patrick, Leissner, Philippe, Berry, Matthew P. R., Wilkinson, Robert J., Kaiser, Karine, Rodrigue, Marc, Woltmann, Gerrit, Haldar, Pranabashis, O’Garra, Anne
Publicado 2018

Detectable Changes in The Blood Transcriptome Are Present after Two Weeks of Antituberculosis Therapy

por Bloom, Chloe I., Graham, Christine M., Berry, Matthew P. R., Wilkinson, Katalin A., Oni, Tolu, Rozakeas, Fotini, Xu, Zhaohui, Rossello-Urgell, Jose, Chaussabel, Damien, Banchereau, Jacques, Pascual, Virginia, Lipman, Marc, Wilkinson, Robert J., O’Garra, Anne
Publicado 2012

HIV–tuberculosis-associated immune reconstitution inflammatory syndrome is characterized by Toll-like receptor and inflammasome signalling

por Lai, Rachel P. J., Meintjes, Graeme, Wilkinson, Katalin A., Graham, Christine M., Marais, Suzaan, Van der Plas, Helen, Deffur, Armin, Schutz, Charlotte, Bloom, Chloe, Munagala, Indira, Anguiano, Esperanza, Goliath, Rene, Maartens, Gary, Banchereau, Jacques, Chaussabel, Damien, O'Garra, Anne, Wilkinson, Robert J.
Publicado 2015

Mouse transcriptome reveals potential signatures of protection and pathogenesis in human tuberculosis

por Moreira-Teixeira, Lúcia, Tabone, Olivier, Graham, Christine M., Singhania, Akul, Stavropoulos, Evangelos, Redford, Paul S., Chakravarty, Probir, Priestnall, Simon L., Suarez-Bonnet, Alejandro, Herbert, Eleanor, Mayer-Barber, Katrin D., Sher, Alan, Fonseca, Kaori L., Sousa, Jeremy, Cá, Baltazar, Verma, Raman, Haldar, Pranabashis, Saraiva, Margarida, O’Garra, Anne
Publicado 2020

An Interferon-Inducible Neutrophil-Driven Blood Transcriptional Signature in Human Tuberculosis

por Berry, Matthew P. R., Graham, Christine M., McNab, Finlay W., Xu, Zhaohui, Bloch, Susannah A.A., Oni, Tolu, Wilkinson, Katalin A., Banchereau, Romain, Skinner, Jason, Wilkinson, Robert J., Quinn, Charles, Blankenship, Derek, Dhawan, Ranju, Cush, John J., Mejias, Asuncion, Ramilo, Octavio, Kon, Onn M., Pascual, Virginia, Banchereau, Jacques, Chaussabel, Damien, O'Garra, Anne
Publicado 2010

Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers

por Bloom, Chloe I., Graham, Christine M., Berry, Matthew P. R., Rozakeas, Fotini, Redford, Paul S., Wang, Yuanyuan, Xu, Zhaohui, Wilkinson, Katalin A., Wilkinson, Robert J., Kendrick, Yvonne, Devouassoux, Gilles, Ferry, Tristan, Miyara, Makoto, Bouvry, Diane, Dominique, Valeyre, Gorochov, Guy, Blankenship, Derek, Saadatian, Mitra, Vanhems, Phillip, Beynon, Huw, Vancheeswaran, Rama, Wickremasinghe, Melissa, Chaussabel, Damien, Banchereau, Jacques, Pascual, Virginia, Ho, Ling-pei, Lipman, Marc, O’Garra, Anne
Publicado 2013

Correction: Transcriptional Blood Signatures Distinguish Pulmonary Tuberculosis, Pulmonary Sarcoidosis, Pneumonias and Lung Cancers

por Bloom, Chloe I., Graham, Christine M., Berry, Matthew P. R., Rozakeas, Fotini, Redford, Paul S., Wang, Yuanyuan, Xu, Zhaohui, Wilkinson, Katalin A., Wilkinson, Robert J., Kendrick, Yvonne, Devouassoux, Gilles, Ferry, Tristan, Miyara, Makoto, Bouvry, Diane, Dominique, Valeyre, Gorochov, Guy, Blankenship, Derek, Saadatian, Mitra, Vanhems, Phillip, Beynon, Huw, Vancheeswaran, Rama, Wickremasinghe, Melissa, Chaussabel, Damien, Banchereau, Jacques, Pascual, Virginia, Ho, Ling-pei, Lipman, Marc, O’Garra, Anne
Publicado 2013

Development of a fixed module repertoire for the analysis and interpretation of blood transcriptome data

por Altman, Matthew C., Rinchai, Darawan, Baldwin, Nicole, Toufiq, Mohammed, Whalen, Elizabeth, Garand, Mathieu, Syed Ahamed Kabeer, Basirudeen, Alfaki, Mohamed, Presnell, Scott R., Khaenam, Prasong, Ayllón-Benítez, Aaron, Mougin, Fleur, Thébault, Patricia, Chiche, Laurent, Jourde-Chiche, Noemie, Phillips, J. Theodore, Klintmalm, Goran, O’Garra, Anne, Berry, Matthew, Bloom, Chloe, Wilkinson, Robert J., Graham, Christine M., Lipman, Marc, Lertmemongkolchai, Ganjana, Bedognetti, Davide, Thiebaut, Rodolphe, Kheradmand, Farrah, Mejias, Asuncion, Ramilo, Octavio, Palucka, Karolina, Pascual, Virginia, Banchereau, Jacques, Chaussabel, Damien
Publicado 2021

Transcriptional profiling unveils type I and II interferon networks in blood and tissues across diseases

por Singhania, Akul, Graham, Christine M., Gabryšová, Leona, Moreira-Teixeira, Lúcia, Stavropoulos, Evangelos, Pitt, Jonathan M., Chakravarty, Probir, Warnatsch, Annika, Branchett, William J., Conejero, Laura, Lin, Jing-Wen, Davidson, Sophia, Wilson, Mark S., Bancroft, Gregory, Langhorne, Jean, Frickel, Eva, Sesay, Abdul K., Priestnall, Simon L., Herbert, Eleanor, Ioannou, Marianna, Wang, Qian, Humphreys, Ian R., Dodd, Jonathan, Openshaw, Peter J. M., Mayer-Barber, Katrin D., Jankovic, Dragana, Sher, Alan, Lloyd, Clare M., Baldwin, Nicole, Chaussabel, Damien, Papayannopoulos, Venizelos, Wack, Andreas, Banchereau, Jacques F., Pascual, Virginia M., O’Garra, Anne
Publicado 2019