A survey of renal impairment pharmacokinetic studies for new oncology drug approvals in the USA from 2010 to early 2015: a focus on development strategies and future directions

por Xiao, Jim J., Chen, Jiyun S., Lum, Bert L., Graham, Richard A.
Publicado 2017

Pharmacokinetics of Ampreloxetine, a Norepinephrine Reuptake Inhibitor, in Healthy Subjects and Adults with Attention-Deficit/Hyperactive Disorder or Fibromyalgia Pain

por Kanodia, Jitendra, Lo, Arthur, Baldwin, R. Michael, Graham, Richard A., Bourdet, David L.
Publicado 2020

A clinical drug–drug interaction study to evaluate the effect of a proton-pump inhibitor, a combined P-glycoprotein/cytochrome 450 enzyme (CYP)3A4 inhibitor, and a CYP2C9 inhibitor...

por Malhi, Vikram, Colburn, Dawn, Williams, Sarah J., Hop, Cornelis E. C. A., Dresser, Mark J., Chandra, Priya, Graham, Richard A.
Publicado 2016

A survey of new oncology drug approvals in the USA from 2010 to 2015: a focus on optimal dose and related postmarketing activities

por Lu, Dan, Lu, Tong, Stroh, Mark, Graham, Richard A., Agarwal, Priya, Musib, Luna, Li, Chi-Chung, Lum, Bert L., Joshi, Amita
Publicado 2016

Leveraging innovative technology to generate drug response phenotypes for the advancement of biomarker‐driven precision dosing

por Oni‐Orisan, Akinyemi, Srinivas, Nithya, Mehta, Krina, Das, Jesmin Lohy, Nguyen, Thu T., Tison, Geoffrey H., Bauer, Scott R., Burian, Maria, Funk, Ryan S., Graham, Richard A.
Publicado 2021

Development of Gut-Selective Pan-Janus Kinase Inhibitor TD-1473 for Ulcerative Colitis: A Translational Medicine Programme

por Sandborn, William J, Nguyen, Deanna D, Beattie, David T, Brassil, Patrick, Krey, Whitney, Woo, Jacky, Situ, Eva, Sana, Reuben, Sandvik, Erik, Pulido-Rios, M Teresa, Bhandari, Raj, Leighton, Jonathan A, Ganeshappa, Ravi, Boyle, David L, Abhyankar, Brihad, Kleinschek, Melanie A, Graham, Richard A, Panes, Julian
Publicado 2020