In Silico Discovery and Subsequent Characterization of Potent 4R-Tauopathy Positron Emission Tomography Radiotracers

por Graham, Thomas J. A., Lindberg, Anton, Tong, Junchao, Stehouwer, Jeffrey S., Vasdev, Neil, Mach, Robert H., Mathis, Chester A.
Publicado 2023

Chalcones and Five-Membered Heterocyclic Isosteres Bind to Alpha Synuclein Fibrils in Vitro

por Hsieh, Chia-Ju, Xu, Kuiying, Lee, Iljung, Graham, Thomas J. A., Tu, Zhude, Dhavale, Dhruva, Kotzbauer, Paul, Mach, Robert H.
Publicado 2018

Metallaphotoredox Aryl and Alkyl Radiomethylation for PET Ligand Discovery

por Pipal, Robert W., Stout, Kenneth T., Musacchio, Patricia Z., Ren, Sumei, Graham, Thomas J. A., Verhoog, Stefan, Gantert, Liza, Lohith, Talakad G., Schmitz, Alexander, Lee, Hsiaoju S., Hesk, David, Hostetler, Eric D., Davies, Ian W., MacMillan, David W. C.
Publicado 2020

Identification of a nanomolar affinity α-synuclein fibril imaging probe by ultra-high throughput in silico screening

por Ferrie, John J., Lengyel-Zhand, Zsofia, Janssen, Bieneke, Lougee, Marshall G., Giannakoulias, Sam, Hsieh, Chia-Ju, Pagar, Vinayak Vishnu, Weng, Chi-Chang, Xu, Hong, Graham, Thomas J. A., Lee, Virginia M.-Y., Mach, Robert H., Petersson, E. James
Publicado 2020