Emerging engineering principles for yield improvement in microbial cell design

por Comba, Santiago, Arabolaza, Ana, Gramajo, Hugo
Publicado 2012

Escherichia coli coculture for de novo production of esters derived of methyl-branched alcohols and multi-methyl branched fatty acids

por Bracalente, Fernando, Sabatini, Martín, Arabolaza, Ana, Gramajo, Hugo
Publicado 2022

Design and testing of a synthetic biology framework for genetic engineering of Corynebacterium glutamicum

por Ravasi, Pablo, Peiru, Salvador, Gramajo, Hugo, Menzella, Hugo G
Publicado 2012

Identification and physiological characterization of phosphatidic acid phosphatase enzymes involved in triacylglycerol biosynthesis in Streptomyces coelicolor

por Comba, Santiago, Menendez-Bravo, Simón, Arabolaza, Ana, Gramajo, Hugo
Publicado 2013

Engineering a Streptomyces coelicolor biosynthesis pathway into Escherichia coli for high yield triglyceride production

por Comba, Santiago, Sabatini, Martín, Menendez-Bravo, Simón, Arabolaza, Ana, Gramajo, Hugo
Publicado 2014

Role of long-chain acyl-CoAs in the regulation of mycolic acid biosynthesis in mycobacteria

por Tsai, Yi Ting, Salzman, Valentina, Cabruja, Matías, Gago, Gabriela, Gramajo, Hugo
Publicado 2017

A novel multidomain acyl-CoA carboxylase in Saccharopolyspora erythraea provides malonyl-CoA for de novo fatty acid biosynthesis

por Livieri, Andrea L., Navone, Laura, Marcellin, Esteban, Gramajo, Hugo, Rodriguez, Eduardo
Publicado 2019

Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria

por Crotta Asis, Agostina, Savoretti, Franco, Cabruja, Matías, Gramajo, Hugo, Gago, Gabriela
Publicado 2021

Metabolically engineered Escherichia coli for efficient production of glycosylated natural products

por Peirú, Salvador, Rodríguez, Eduardo, Menzella, Hugo G., Carney, John R., Gramajo, Hugo
Publicado 2008

Identification of FadAB Complexes Involved in Fatty Acid β-Oxidation in Streptomyces coelicolor and Construction of a Triacylglycerol Overproducing strain

por Menendez-Bravo, Simón, Paganini, Julián, Avignone-Rossa, Claudio, Gramajo, Hugo, Arabolaza, Ana
Publicado 2017

A conditional mutant of the fatty acid synthase unveils unexpected cross talks in mycobacterial lipid metabolism

por Cabruja, Matías, Mondino, Sonia, Tsai, Yi Ting, Lara, Julia, Gramajo, Hugo, Gago, Gabriela
Publicado 2017

Pleiotropic Effect of AccD5 and AccE5 Depletion in Acyl-Coenzyme A Carboxylase Activity and in Lipid Biosynthesis in Mycobacteria

por Bazet Lyonnet, Bernardo, Diacovich, Lautaro, Cabruja, Matías, Bardou, Fabienne, Quémard, Annaïk, Gago, Gabriela, Gramajo, Hugo
Publicado 2014

High cell density production of multimethyl-branched long-chain esters in Escherichia coli and determination of their physicochemical properties

por Menendez-Bravo, Simón, Roulet, Julia, Sabatini, Martín, Comba, Santiago, Dunn, Robert, Gramajo, Hugo, Arabolaza, Ana
Publicado 2016

3-methylcrotonyl Coenzyme A (CoA) carboxylase complex is involved in the Xanthomonas citri subsp. citri lifestyle during citrus infection

por Tomassetti, Mauro, Garavaglia, Betiana S., Vranych, Cecilia V., Gottig, Natalia, Ottado, Jorgelina, Gramajo, Hugo, Diacovich, Lautaro
Publicado 2018

Correction: Pleiotropic Effect of AccD5 and AccE5 Depletion in Acyl-Coenzyme A Carboxylase Activity and in Lipid Biosynthesis in Mycobacteria

por Lyonnet, Bernardo Bazet, Diacovich, Lautaro, Cabruja, Matías, Bardou, Fabienne, Quémard, Annaïk, Gago, Gabriela, Gramajo, Hugo
Publicado 2020

Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase

por Sabatini, Martin, Comba, Santiago, Altabe, Silvia, Recio‐Balsells, Alejandro I., Labadie, Guillermo R., Takano, Eriko, Gramajo, Hugo, Arabolaza, Ana
Publicado 2018

Mycobacterium tuberculosis FasR senses long fatty acyl-CoA through a tunnel and a hydrophobic transmission spine

por Lara, Julia, Diacovich, Lautaro, Trajtenberg, Felipe, Larrieux, Nicole, Malchiodi, Emilio L., Fernández, Marisa M., Gago, Gabriela, Gramajo, Hugo, Buschiazzo, Alejandro
Publicado 2020

Polar protein Wag31 both activates and inhibits cell wall metabolism at the poles and septum

por Habibi Arejan, Neda, Ensinck, Delfina, Diacovich, Lautaro, Patel, Parthvi Bharatkumar, Quintanilla, Samantha Y., Emami Saleh, Arash, Gramajo, Hugo, Boutte, Cara C.
Publicado 2023

Expression and purification of untagged GlnK proteins from actinobacteria

por Gerhardt, Edileusa C.M., Moure, Vivian R., Souza, Andrey W., Pedrosa, Fabio O., Souza, Emanuel M., Diacovich, Lautaro, Gramajo, Hugo, Huergo, Luciano F.
Publicado 2017

FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence of Mycobacterium tuberculosis

por Mondino, Sonia, Vázquez, Cristina L., Cabruja, Matías, Sala, Claudia, Cazenave-Gassiot, Amaury, Blanco, Federico C., Wenk, Markus R., Bigi, Fabiana, Cole, Stewart T., Gramajo, Hugo, Gago, Gabriela
Publicado 2020