Lower cardiotoxicity of CPX-351 relative to daunorubicin plus cytarabine free-drug combination in hiPSC-derived cardiomyocytes in vitro

por Fortin, Marie C., LaCroix, Andrew S., Grammatopoulos, Tom N., Tan, Lei, Wang, Qi, Manca, Dino
Publicado 2023

Farnesyltransferase inhibitor LNK-754 attenuates axonal dystrophy and reduces amyloid pathology in mice

por Cuddy, Leah K., Alia, Alia O., Salvo, Miranda A., Chandra, Sidhanth, Grammatopoulos, Tom N., Justman, Craig J., Lansbury, Peter T., Mazzulli, Joseph R., Vassar, Robert
Publicado 2022

Neurotransplantation of stem cells genetically modified to express human dopamine transporter reduces alcohol consumption

por Grammatopoulos, Tom N, Jones, Susan M, Yoshimura, Masami, Hoover, Brian R, Das, Mita, Snyder, Evan Y, Larson, Gaynor A, Zahniser, Nancy R, Tabakoff, Boris, Zawada, W Michael
Publicado 2010

Angiotensin type 1 receptor antagonist losartan, reduces MPTP-induced degeneration of dopaminergic neurons in substantia nigra

por Grammatopoulos, Tom N, Jones, Susan M, Ahmadi, Ferogh A, Hoover, Brian R, Snell, Lawrence D, Skoch, Jesse, Jhaveri, Vimal V, Poczobutt, Andy M, Weyhenmeyer, James A, Zawada, W Michael
Publicado 2007

Advances in the quantification of mitochondrial function in primary human immune cells through extracellular flux analysis

por Nicholas, Dequina, Proctor, Elizabeth A., Raval, Forum M., Ip, Blanche C., Habib, Chloe, Ritou, Eleni, Grammatopoulos, Tom N., Steenkamp, Devin, Dooms, Hans, Apovian, Caroline M., Lauffenburger, Douglas A., Nikolajczyk, Barbara S.
Publicado 2017

Identification of peripheral vascular function measures and circulating biomarkers of mitochondrial function in patients with mitochondrial disease

por van Kraaij, Sebastiaan J. W., Pereira, Diana R., Smal, Bastiaan, Summo, Luciana, Konkel, Anne, Lossie, Janine, Busjahn, Andreas, Grammatopoulos, Tom N., Klaassen, Erica, Fischer, Robert, Schunck, Wolf‐Hagen, Gal, Pim, Moerland, Matthijs
Publicado 2023

Application of a Mechanistic Model to Evaluate Putative Mechanisms of Tolvaptan Drug-Induced Liver Injury and Identify Patient Susceptibility Factors

por Woodhead, Jeffrey L., Brock, William J., Roth, Sharin E., Shoaf, Susan E., Brouwer, Kim L.R., Church, Rachel, Grammatopoulos, Tom N., Stiles, Linsey, Siler, Scott Q., Howell, Brett A., Mosedale, Merrie, Watkins, Paul B., Shoda, Lisl K.M.
Publicado 2017