Innate immune signaling in Drosophila shifts anabolic lipid metabolism from triglyceride storage to phospholipid synthesis to support immune function

por Martínez, Brittany A., Hoyle, Rosalie G., Yeudall, Scott, Granade, Mitchell E., Harris, Thurl E., Castle, J. David, Leitinger, Norbert, Bland, Michelle L.
Publicado 2020

Chemoproteomic profiling of kinases in live cells using electrophilic sulfonyl triazole probes

por Huang, Tao, Hosseinibarkooie, Seyyedmohsen, Borne, Adam L., Granade, Mitchell E., Brulet, Jeffrey W., Harris, Thurl E., Ferris, Heather A., Hsu, Ku-Lung
Publicado 2021

Loss of Diacylglycerol Kinase α Enhances Macrophage Responsiveness

por Manigat, Laryssa C., Granade, Mitchell E., Taori, Suchet, Miller, Charlotte Anne, Vass, Luke R., Zhong, Xiao-Ping, Harris, Thurl E., Purow, Benjamin W.
Publicado 2021

Reprogramming fatty acyl specificity of lipid kinases via C1 domain engineering

por Ware, Timothy B., Franks, Caroline E., Granade, Mitchell E., Zhang, Mingxing, Kim, Kee-Beom, Park, Kwon-Sik, Gahlmann, Andreas, Harris, Thurl E., Hsu, Ku-Lung
Publicado 2020

Feeding desensitizes A1 adenosine receptors in adipose through FOXO1-mediated transcriptional regulation

por Granade, Mitchell E., Hargett, Stefan R., Lank, Daniel S., Lemke, Michael C., Luse, Melissa A., Isakson, Brant E., Bochkis, Irina M., Linden, Joel, Harris, Thurl E.
Publicado 2022

Adipocyte lipolysis drives acute stress-induced insulin resistance

por Raje, Vidisha, Ahern, Katelyn W., Martinez, Brittany A., Howell, Nancy L., Oenarto, Vici, Granade, Mitchell E., Kim, Jae Woo, Tundup, Smanla, Bottermann, Katharina, Gödecke, Axel, Keller, Susanna R., Kadl, Alexandra, Bland, Michelle L., Harris, Thurl E.
Publicado 2020