High-throughput single-cell chromatin accessibility CRISPR screens enable unbiased identification of regulatory networks in cancer

por Pierce, Sarah E., Granja, Jeffrey M., Greenleaf, William J.
Publicado 2021

ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

por Granja, Jeffrey M., Corces, M. Ryan, Pierce, Sarah E., Bagdatli, S. Tansu, Choudhry, Hani, Chang, Howard Y., Greenleaf, William J.
Publicado 2021

Author Correction: ArchR is a scalable software package for integrative single-cell chromatin accessibility analysis

por Granja, Jeffrey M., Corces, M. Ryan, Pierce, Sarah E., Bagdatli, S. Tansu, Choudhry, Hani, Chang, Howard Y., Greenleaf, William J.
Publicado 2021

Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity

por Leylek, Rebecca, Alcántara-Hernández, Marcela, Granja, Jeffrey M., Chavez, Michael, Perez, Kimberly, Diaz, Oscar R., Li, Rui, Satpathy, Ansuman T., Chang, Howard Y., Idoyaga, Juliana
Publicado 2020

Polycomb-mediated genome architecture enables long-range spreading of H3K27 methylation

por Kraft, Katerina, Yost, Kathryn E., Murphy, Sedona E., Magg, Andreas, Long, Yicheng, Corces, M. Ryan, Granja, Jeffrey M., Wittler, Lars, Mundlos, Stefan, Cech, Thomas R., Boettiger, Alistair N., Chang, Howard Y.
Publicado 2022

Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis

por Liu, Qian, Zaba, Lisa, Satpathy, Ansuman T., Longmire, Michelle, Zhang, Wen, Li, Kun, Granja, Jeffrey, Guo, Chuang, Lin, Jun, Li, Rui, Tolentino, Karen, Kania, Gabriela, Distler, Oliver, Fiorentino, David, Chung, Lorinda, Qu, Kun, Chang, Howard Y.
Publicado 2020

Author Correction: Chromatin accessibility landscapes of skin cells in systemic sclerosis nominate dendritic cells in disease pathogenesis

por Liu, Qian, Zaba, Lisa C., Satpathy, Ansuman T., Longmire, Michelle, Zhang, Wen, Li, Kun, Granja, Jeffrey, Guo, Chuang, Lin, Jun, Li, Rui, Tolentino, Karen, Kania, Gabriela, Distler, Oliver, Fiorentino, David, Chung, Lorinda, Qu, Kun, Chang, Howard Y.
Publicado 2020

An Nfil3–Zeb2–Id2 pathway imposes Irf8 enhancer switching during cDC1 development

por Bagadia, Prachi, Huang, Xiao, Liu, Tiantian, Durai, Vivek, Grajales-Reyes, Gary E., Nitschke, Maximilian, Modrusan, Zora, Granja, Jeffrey M., Satpathy, Ansuman T., Briseño, Carlos G., Gargaro, Marco, Iwata, Arifumi, Kim, Sunkyung, Chang, Howard Y., Shaw, Andrey S., Murphy, Theresa L., Murphy, Kenneth M.
Publicado 2019

Clonal replacement of tumor-specific T cells following PD-1 blockade

por Yost, Kathryn E., Satpathy, Ansuman T., Wells, Daniel K., Qi, Yanyan, Wang, Chunlin, Kageyama, Robin, McNamara, Katherine, Granja, Jeffrey M., Sarin, Kavita Y., Brown, Ryanne A., Gupta, Rohit K., Curtis, Christina, Bucktrout, Samantha L., Davis, Mark M., Chang, Anne Lynn S., Chang, Howard Y.
Publicado 2019

c-Jun overexpression in CAR T cells induces exhaustion resistance

por Lynn, Rachel C., Weber, Evan W., Sotillo, Elena, Gennert, David, Xu, Peng, Good, Zinaida, Anbunathan, Hima, Lattin, John, Jones, Robert, Tieu, Victor, Nagaraja, Surya, Granja, Jeffrey, DeBourcy, Charles, Majzner, Robbie, Satpathy, Ansuman T., Quake, Stephen R., Monje, Michelle, Chang, Howard, Mackall, Crystal L.
Publicado 2019

Single-cell epigenomic analyses implicate candidate causal variants at inherited risk loci for Alzheimer’s and Parkinson’s diseases

por Corces, M. Ryan, Shcherbina, Anna, Kundu, Soumya, Gloudemans, Michael J., Frésard, Laure, Granja, Jeffrey M., Louie, Bryan H., Eulalio, Tiffany, Shams, Shadi, Bagdatli, S. Tansu, Mumbach, Maxwell R., Liu, Boxiang, Montine, Kathleen S., Greenleaf, William J., Kundaje, Anshul, Montgomery, Stephen B., Chang, Howard Y., Montine, Thomas J.
Publicado 2020

Cryptic activation of an Irf8 enhancer governs cDC1 fate specification

por Durai, Vivek, Bagadia, Prachi, Granja, Jeffrey M., Satpathy, Ansuman T., Kulkarni, Devesha H., Davidson, Jesse T., Wu, Renee, Patel, Swapneel J., Iwata, Arifumi, Liu, Tiantian, Huang, Xiao, Briseño, Carlos G., Grajales-Reyes, Gary E., Wöhner, Miriam, Tagoh, Hiromi, Kee, Barbara L., Newberry, Rodney D., Busslinger, Meinrad, Chang, Howard Y., Murphy, Theresa L., Murphy, Kenneth M.
Publicado 2019

Transcript-indexed ATAC-seq for precision immune profiling

por Satpathy, Ansuman T., Saligrama, Naresha, Buenrostro, Jason D., Wei, Yuning, Wu, Beijing, Rubin, Adam J., Granja, Jeffrey M., Lareau, Caleb A., Li, Rui, Qi, Yanyan, Parker, Kevin R., Mumbach, Maxwell R., Serratelli, William S., Gennert, David G., Schep, Alicia N., Corces, M. Ryan, Khodadoust, Michael S., Kim, Youn H., Khavari, Paul A., Greenleaf, William J., Davis, Mark M., Chang, Howard Y.
Publicado 2018

GWAS for systemic sclerosis identifies multiple risk loci and highlights fibrotic and vasculopathy pathways

por López-Isac, Elena, Acosta-Herrera, Marialbert, Kerick, Martin, Assassi, Shervin, Satpathy, Ansuman T., Granja, Jeffrey, Mumbach, Maxwell R., Beretta, Lorenzo, Simeón, Carmen P., Carreira, Patricia, Ortego-Centeno, Norberto, Castellvi, Ivan, Bossini-Castillo, Lara, Carmona, F. David, Orozco, Gisela, Hunzelmann, Nicolas, Distler, Jörg H. W., Franke, Andre, Lunardi, Claudio, Moroncini, Gianluca, Gabrielli, Armando, de Vries-Bouwstra, Jeska, Wijmenga, Cisca, Koeleman, Bobby P. C., Nordin, Annika, Padyukov, Leonid, Hoffmann-Vold, Anna-Maria, Lie, Benedicte, Proudman, Susanna, Stevens, Wendy, Nikpour, Mandana, Vyse, Timothy, Herrick, Ariane L., Worthington, Jane, Denton, Christopher P., Allanore, Yannick, Brown, Matthew A., Radstake, Timothy R. D. J., Fonseca, Carmen, Chang, Howard Y., Mayes, Maureen D., Martin, Javier
Publicado 2019