Disrupting autophagy in FLT3-mutant acute myeloid leukemia

por Grant, Steven
Publicado 2022

Enhancing proteotoxic stress as an anticancer strategy

por Grant, Steven
Publicado 2011

HDAC inhibitors repress the polycomb protein BMI1

por Grant, Steven
Publicado 2010

Selectively killing transformed cells through proteasome inhibition

por Grant, Steven
Publicado 2009

Targeting Chk1 in the replicative stress response

por Dai, Yun, Grant, Steven
Publicado 2010

Rational Combinations of Targeted Agents in AML

por Bose, Prithviraj, Grant, Steven
Publicado 2015

Coordinate PI3K pathway and Bcl-2 family disruption in AML

por Bose, Prithviraj, Rahmani, Mohamed, Grant, Steven
Publicado 2012

Secondary-Type Mutations in Acute Myeloid Leukemia: Updates from ELN 2022

por Bouligny, Ian M., Maher, Keri R., Grant, Steven
Publicado 2023

Mechanisms of myeloid leukemogenesis: Current perspectives and therapeutic objectives

por Bouligny, Ian M., Maher, Keri R., Grant, Steven
Publicado 2023

Augmenting Venetoclax Activity Through Signal Transduction in AML

por Bouligny, Ian Michael, Maher, Keri Renee, Grant, Steven
Publicado 2023

Synergistic Interactions between the Hypomethylating Agent Thio-Deoxycytidine and Venetoclax in Myelodysplastic Syndrome Cells

por Hu, Xiaoyan, Li, Lin, Nkwocha, Jewel, Sharma, Kanika, Zhou, Liang, Grant, Steven
Publicado 2023

MEK Inhibitors Potentiate Dexamethasone Lethality in Acute Lymphoblastic Leukemia Cells through the Pro-apoptotic Molecule BIM

por Rambal, Anila A., Panaguiton, Zarah Liz G., Kramer, Lora, Grant, Steven, Harada, Hisashi
Publicado 2009

Positive transcription elongation factor b (P-TEFb) is a therapeutic target in human multiple myeloma

por Zhang, Yu, Zhou, Liang, Leng, Yun, Dai, Yun, Orlowski, Robert Z., Grant, Steven
Publicado 2017

Homoharringtonine interacts synergistically with bortezomib in NHL cells through MCL-1 and NOXA-dependent mechanisms

por Nguyen, Tri, Parker, Rebecca, Zhang, Yu, Hawkins, Elisa, Kmieciak, Maciej, Craun, William, Grant, Steven
Publicado 2018

Non-canonical role for the ataxia-telangiectasia-Rad3 pathway in STAT3 activation in human multiple myeloma cells

por Li, Lin, Hu, Xiaoyan, Nkwocha, Jewel, Sharma, Kanika, Kmieciak, Maciej, Mann, Hashim, Zhou, Liang, Grant, Steven
Publicado 2023

Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin's lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms

por Nguyen, Tri, Parker, Rebecca, Hawkins, Elisa, Holkova, Beata, Yazbeck, Victor, Kolluri, Akhil, Kmieciak, Maciej, Rahmani, Mohamed, Grant, Steven
Publicado 2017

Correction: Synergistic interactions between PLK1 and HDAC inhibitors in non-Hodgkin’s lymphoma cells occur in vitro and in vivo and proceed through multiple mechanisms

por Nguyen, Tri, Parker, Rebecca, Hawkins, Elisa, Holkova, Beata, Yazbeck, Victor, Kolluri, Akhil, Kmieciak, Maciej, Rahmani, Mohamed, Grant, Steven
Publicado 2019

Flavopiridol enhances ABT-199 sensitivity in unfavourable-risk multiple myeloma cells in vitro and in vivo

por Zhou, Liang, Zhang, Yu, Sampath, Deepak, Leverson, Joel, Dai, Yun, Kmieciak, Maciej, Nguyen, Matthew, Orlowski, Robert Z, Grant, Steven
Publicado 2018

Histone deacetylase inhibitors restore toxic BH3 domain protein expression in anoikis-resistant mammary and brain cancer stem cells, thereby enhancing the response to anti-ERBB1/ER...

por Cruickshanks, Nichola, Hamed, Hossein A, Booth, Laurence, Tavallai, Seyedmehrad, Syed, Jahangir, Sajithlal, Gangadharan B, Grant, Steven, Poklepovic, Andrew, Dent, Paul
Publicado 2013

The IAP antagonist birinapant potentiates bortezomib anti-myeloma activity in vitro and in vivo

por Zhou, Liang, Zhang, Yu, Leng, Yun, Dai, Yun, Kmieciak, Maciej, Kramer, Lora, Sharma, Kanika, Wang, Yan, Craun, William, Grant, Steven
Publicado 2019