The Importance of REST for Development and Function of Beta Cells

por Martin, David, Grapin-Botton, Anne
Publicado 2017

Towards a better understanding of diabetes mellitus using organoid models

por Beydag-Tasöz, Belin Selcen, Yennek, Siham, Grapin-Botton, Anne
Publicado 2023

Retinoic Acid Signaling Organizes Endodermal Organ Specification along the Entire Antero-Posterior Axis

por Bayha, Elke, Jørgensen, Mette C., Serup, Palle, Grapin-Botton, Anne
Publicado 2009

Self-organization of organoids from endoderm-derived cells

por Lewis, Allison, Keshara, Rashmiparvathi, Kim, Yung Hae, Grapin-Botton, Anne
Publicado 2020

Cell Cycle–Dependent Differentiation Dynamics Balances Growth and Endocrine Differentiation in the Pancreas

por Kim, Yung Hae, Larsen, Hjalte List, Rué, Pau, Lemaire, Laurence A., Ferrer, Jorge, Grapin-Botton, Anne
Publicado 2015

Single-Cell Gene Expression Analysis of a Human ESC Model of Pancreatic Endocrine Development Reveals Different Paths to β-Cell Differentiation

por Petersen, Maja Borup Kjær, Azad, Ajuna, Ingvorsen, Camilla, Hess, Katja, Hansson, Mattias, Grapin-Botton, Anne, Honoré, Christian
Publicado 2017

Stochastic priming and spatial cues orchestrate heterogeneous clonal contribution to mouse pancreas organogenesis

por Larsen, Hjalte List, Martín-Coll, Laura, Nielsen, Alexander Valentin, Wright, Christopher V. E., Trusina, Ala, Kim, Yung Hae, Grapin-Botton, Anne
Publicado 2017

Deconstructing the principles of ductal network formation in the pancreas

por Dahl-Jensen, Svend Bertel, Yennek, Siham, Flasse, Lydie, Larsen, Hjalte List, Sever, Dror, Karremore, Gopal, Novak, Ivana, Sneppen, Kim, Grapin-Botton, Anne
Publicado 2018

Combined Optical Coherence and Fluorescence Microscopy to assess dynamics and specificity of pancreatic beta-cell tracers

por Berclaz, Corinne, Pache, Christophe, Bouwens, Arno, Szlag, Daniel, Lopez, Antonio, Joosten, Lieke, Ekim, Selen, Brom, Maarten, Gotthardt, Martin, Grapin-Botton, Anne, Lasser, Theo
Publicado 2015

Diabetes imaging—quantitative assessment of islets of Langerhans distribution in murine pancreas using extended-focus optical coherence microscopy

por Berclaz, Corinne, Goulley, Joan, Villiger, Martin, Pache, Christophe, Bouwens, Arno, Martin-Williams, Erica, Van de Ville, Dimitri, Davison, Anthony C., Grapin-Botton, Anne, Lasser, Theo
Publicado 2012

Wnt4 is heterogeneously activated in maturing β-cells to control calcium signaling, metabolism and function

por Katsumoto, Keiichi, Yennek, Siham, Chen, Chunguang, Silva, Luis Fernando Delgadillo, Traikov, Sofia, Sever, Dror, Azad, Ajuna, Shan, Jingdong, Vainio, Seppo, Ninov, Nikolay, Speier, Stephan, Grapin-Botton, Anne
Publicado 2022

Long-term feeder-free culture of human pancreatic progenitors on fibronectin or matrix-free polymer potentiates β cell differentiation

por Nakamura, Akiko, Wong, Yan Fung, Venturato, Andrea, Michaut, Magali, Venkateswaran, Seshasailam, Santra, Mithun, Gonçalves, Carla, Larsen, Michael, Leuschner, Marit, Kim, Yung Hae, Brickman, Joshua, Bradley, Mark, Grapin-Botton, Anne
Publicado 2022

Emerging principles of primary cilia dynamics in controlling tissue organization and function

por Gopalakrishnan, Jay, Feistel, Kerstin, Friedrich, Benjamin M, Grapin‐Botton, Anne, Jurisch‐Yaksi, Nathalie, Mass, Elvira, Mick, David U, Müller, Roman‐Ulrich, May‐Simera, Helen, Schermer, Bernhard, Schmidts, Miriam, Walentek, Peter, Wachten, Dagmar
Publicado 2023

COUP-TFII Controls Mouse Pancreatic β-Cell Mass through GLP-1-β-Catenin Signaling Pathways

por Boutant, Marie, Ramos, Oscar Henrique Pereira, Tourrel-Cuzin, Cécile, Movassat, Jamileh, Ilias, Anissa, Vallois, David, Planchais, Julien, Pégorier, Jean-Paul, Schuit, Frans, Petit, Patrice X., Bossard, Pascale, Maedler, Kathrin, Grapin-Botton, Anne, Vasseur-Cognet, Mireille
Publicado 2012

A 3D system to model human pancreas development and its reference single-cell transcriptome atlas identify signaling pathways required for progenitor expansion

por Gonçalves, Carla A., Larsen, Michael, Jung, Sascha, Stratmann, Johannes, Nakamura, Akiko, Leuschner, Marit, Hersemann, Lena, Keshara, Rashmiparvathi, Perlman, Signe, Lundvall, Lene, Thuesen, Lea Langhoff, Hare, Kristine Juul, Amit, Ido, Jørgensen, Anne, Kim, Yung Hae, del Sol, Antonio, Grapin-Botton, Anne
Publicado 2021

Partial promoter substitutions generating transcriptional sentinels of diverse signaling pathways in embryonic stem cells and mice

por Serup, Palle, Gustavsen, Carsten, Klein, Tino, Potter, Leah A., Lin, Robert, Mullapudi, Nandita, Wandzioch, Ewa, Hines, Angela, Davis, Ashley, Bruun, Christine, Engberg, Nina, Petersen, Dorthe R., Peterslund, Janny M. L., MacDonald, Raymond J., Grapin-Botton, Anne, Magnuson, Mark A., Zaret, Kenneth S.
Publicado 2012

The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates

por Tsonkova, Violeta Georgieva, Sand, Fredrik Wolfhagen, Wolf, Xenia Asbæk, Grunnet, Lars Groth, Kirstine Ringgaard, Anna, Ingvorsen, Camilla, Winkel, Louise, Kalisz, Mark, Dalgaard, Kevin, Bruun, Christine, Fels, Johannes Josef, Helgstrand, Charlotte, Hastrup, Sven, Öberg, Fredrik Kryh, Vernet, Erik, Sandrini, Michael Paolo Bastner, Shaw, Allan Christian, Jessen, Carsten, Grønborg, Mads, Hald, Jacob, Willenbrock, Hanni, Madsen, Dennis, Wernersson, Rasmus, Hansson, Lena, Jensen, Jan Nygaard, Plesner, Annette, Alanentalo, Tomas, Petersen, Maja Borup Kjær, Grapin-Botton, Anne, Honoré, Christian, Ahnfelt-Rønne, Jonas, Hecksher-Sørensen, Jacob, Ravassard, Philippe, Madsen, Ole D., Rescan, Claude, Frogne, Thomas
Publicado 2017