Integrated genomics of susceptibility to alkylator-induced leukemia in mice

por Cahan, Patrick, Graubert, Timothy A
Publicado 2010

Biology of secondary leukemia

por Brunner, Andrew M., Graubert, Timothy A.
Publicado 2018

Targeting R-loop-associated ATR response in myelodysplastic syndrome

por Nguyen, Hai Dang, Zou, Lee, Graubert, Timothy A.
Publicado 2019

The impact of copy number variation on local gene expression in mouse hematopoietic stem/progenitor cells

por Cahan, Patrick, Li, Yedda, Izumi, Masayo, Graubert, Timothy A.
Publicado 2009

POU4F1 is associated with t(8;21) acute myeloid leukemia and contributes directly to its unique transcriptional signature

por Fortier, Julie M., Payton, Jacqueline E., Cahan, Patrick, Ley, Timothy J., Walter, Matthew J., Graubert, Timothy A.
Publicado 2010

Structural Variation of the Mouse Natural Killer Gene Complex

por Higuchi, Darryl A., Cahan, Patrick, Gao, Jian, Ferris, Stephen T., Poursine-Laurent, Jennifer, Graubert, Timothy A., Yokoyama, Wayne M.
Publicado 2010

wuHMM: a robust algorithm to detect DNA copy number variation using long oligonucleotide microarray data

por Cahan, Patrick, Godfrey, Laura E., Eis, Peggy S., Richmond, Todd A., Selzer, Rebecca R., Brent, Michael, McLeod, Howard L., Ley, Timothy J., Graubert, Timothy A.
Publicado 2008

Integrated Genomic Analysis Implicates Haploinsufficiency of Multiple Chromosome 5q31.2 Genes in De Novo Myelodysplastic Syndromes Pathogenesis

por Graubert, Timothy A., Payton, Michelle A., Shao, Jin, Walgren, Richard A., Monahan, Ryan S., Frater, John L., Walshauser, Mark A., Martin, Mike G., Kasai, Yumi, Walter, Matthew J.
Publicado 2009

A High-Resolution Map of Segmental DNA Copy Number Variation in the Mouse Genome

por Graubert, Timothy A, Cahan, Patrick, Edwin, Deepa, Selzer, Rebecca R, Richmond, Todd A, Eis, Peggy S, Shannon, William D, Li, Xia, McLeod, Howard L, Cheverud, James M, Ley, Timothy J
Publicado 2007

U2AF1 Mutations Alter Sequence Specificity of pre-mRNA Binding and Splicing

por Okeyo-Owuor, Theresa, White, Brian S., Chatrikhi, Rakesh, Mohan, Dipika R., Kim, Sanghyun, Griffith, Malachi, Ding, Li, Ketkar-Kulkarni, Shamika, Hundal, Jasreet, Laird, Kholiswa M., Kielkopf, Clara L., Ley, Timothy J., Walter, Matthew J., Graubert, Timothy A.
Publicado 2014

Functional analysis of a chromosomal deletion associated with myelodysplastic syndromes using isogenic human induced pluripotent stem cells

por Kotini, Andriana G, Chang, Chan-Jung, Boussaad, Ibrahim, Delrow, Jeffrey J, Dolezal, Emily K, Nagulapally, Abhinav B, Perna, Fabiana, Fishbein, Gregory A, Klimek, Virginia M, Hawkins, R David, Huangfu, Danwei, Murry, Charles E, Graubert, Timothy, Nimer, Stephen D, Papapetrou, Eirini P
Publicado 2015

Mutant U2AF1-expressing cells are sensitive to pharmacological modulation of the spliceosome

por Shirai, Cara Lunn, White, Brian S., Tripathi, Manorama, Tapia, Roberto, Ley, James N., Ndonwi, Matthew, Kim, Sanghyun, Shao, Jin, Carver, Alexa, Saez, Borja, Fulton, Robert S., Fronick, Catrina, O'Laughlin, Michelle, Lagisetti, Chandraiah, Webb, Thomas R., Graubert, Timothy A., Walter, Matthew J.
Publicado 2017

Recurrent DNMT3A Mutations in Patients with Myelodysplastic Syndromes

por Walter, Matthew J., Ding, Li, Shen, Dong, Shao, Jin, Grillot, Marcus, McLellan, Michael, Fulton, Robert, Schmidt, Heather, Kalicki-Veizer, Joelle, O’Laughlin, Michelle, Kandoth, Cyriac, Baty, Jack, Westervelt, Peter, DiPersio, John F., Mardis, Elaine R, Wilson, Richard K., Ley, Timothy J., Graubert, Timothy A.
Publicado 2011

SciClone: Inferring Clonal Architecture and Tracking the Spatial and Temporal Patterns of Tumor Evolution

por Miller, Christopher A., White, Brian S., Dees, Nathan D., Griffith, Malachi, Welch, John S., Griffith, Obi L., Vij, Ravi, Tomasson, Michael H., Graubert, Timothy A., Walter, Matthew J., Ellis, Matthew J., Schierding, William, DiPersio, John F., Ley, Timothy J., Mardis, Elaine R., Wilson, Richard K., Ding, Li
Publicado 2014

Prognostic Understanding, Quality of Life, and Mood in Patients Undergoing Hematopoietic Stem Cell Transplantation

por El-Jawahri, Areej, Traeger, Lara, Kuzmuk, Kailyn, Eusebio, Justin, Vandusen, Harry, Keenan, Tanya, Shin, Jennifer, Gallagher, Emily R., Greer, Joseph A., Pirl, William F., Jackson, Vicki A., Ballen, Karen K, Spitzer, Thomas R., Graubert, Timothy A., McAfee, Steven, Dey, Bimalangshu, Chen, Yi-Bin A., Temel, Jennifer S.
Publicado 2015

Clonal Architecture of Secondary Acute Myeloid Leukemia Defined by Single-Cell Sequencing

por Hughes, Andrew E. O., Magrini, Vincent, Demeter, Ryan, Miller, Christopher A., Fulton, Robert, Fulton, Lucinda L., Eades, William C., Elliott, Kevin, Heath, Sharon, Westervelt, Peter, Ding, Li, Conrad, Donald F., White, Brian S., Shao, Jin, Link, Daniel C., DiPersio, John F., Mardis, Elaine R., Wilson, Richard K., Ley, Timothy J., Walter, Matthew J., Graubert, Timothy A.
Publicado 2014

The Role of TP53 Mutations in the Origin and Evolution of Therapy-Related AML

por Wong, Terrence N., Ramsingh, Giridharan, Young, Andrew L., Miller, Christopher A., Touma, Waseem, Welch, John S., Lamprecht, Tamara L., Shen, Dong, Hundal, Jasreet, Fulton, Robert S., Heath, Sharon, Baty, Jack D., Klco, Jeffery M., Ding, Li, Mardis, Elaine R., Westervelt, Peter, DiPersio, John F., Walter, Matthew J., Graubert, Timothy A., Ley, Timothy J., Druley, Todd, Link, Daniel C., Wilson, Richard K.
Publicado 2014

Dynamic Changes in the Clonal Structure of MDS and AML in Response to Epigenetic Therapy

por Uy, Geoffrey L., Duncavage, Eric J., Chang, Gue Su, Jacoby, Meagan A., Miller, Christopher A., Shao, Jin, Heath, Sharon, Elliott, Kevin, Reinick, Teresa, Fulton, Robert S., Fronick, Catrina C., O’Laughlin, Michelle, Ganel, Liron, Abboud, Camille N., Cashen, Amanda F., DiPersio, John F., Wilson, Richard K, Link, Daniel C., Welch, John S., Ley, Timothy J., Graubert, Timothy A., Westervelt, Peter, Walter, Matthew J.
Publicado 2016

Cellular stressors contribute to the expansion of hematopoietic clones of varying leukemic potential

por Wong, Terrence N., Miller, Christopher A., Jotte, Matthew R. M., Bagegni, Nusayba, Baty, Jack D., Schmidt, Amy P., Cashen, Amanda F., Duncavage, Eric J., Helton, Nichole M., Fiala, Mark, Fulton, Robert S., Heath, Sharon E., Janke, Megan, Luber, Kierstin, Westervelt, Peter, Vij, Ravi, DiPersio, John F., Welch, John S., Graubert, Timothy A., Walter, Matthew J., Ley, Timothy J., Link, Daniel C.
Publicado 2018

Phase I study of the aurora A kinase inhibitor alisertib with induction chemotherapy in patients with acute myeloid leukemia

por Fathi, Amir T., Wander, Seth A., Blonquist, Traci M., Brunner, Andrew M., Amrein, Philip C., Supko, Jeffrey, Hermance, Nicole M., Manning, Amity L., Sadrzadeh, Hossein, Ballen, Karen K., Attar, Eyal C., Graubert, Timothy A., Hobbs, Gabriela, Joseph, Christelle, Perry, Ashley M., Burke, Meghan, Silver, Regina, Foster, Julia, Bergeron, Meghan, Ramos, Aura Y., Som, Tina T., Fishman, Kaitlyn M., McGregor, Kristin L., Connolly, Christine, Neuberg, Donna S., Chen, Yi-Bin
Publicado 2017