Ensuring reliability of safety-critical clinical applications of computational cardiac models

por Pathmanathan, Pras, Gray, Richard A.
Publicado 2013

Filament Dynamics during Simulated Ventricular Fibrillation in a High-Resolution Rabbit Heart

por Pathmanathan, Pras, Gray, Richard A.
Publicado 2015

A Parsimonious Model of the Rabbit Action Potential Elucidates the Minimal Physiological Requirements for Alternans and Spiral Wave Breakup

por Gray, Richard A., Pathmanathan, Pras
Publicado 2016

Validation and Trustworthiness of Multiscale Models of Cardiac Electrophysiology

por Pathmanathan, Pras, Gray, Richard A.
Publicado 2018

Patient-Specific Cardiovascular Computational Modeling: Diversity of Personalization and Challenges

por Gray, Richard A., Pathmanathan, Pras
Publicado 2018

A computational modeling framework for pre-clinical evaluation of cardiac mapping systems

por Galappaththige, Suran, Pathmanathan, Pras, Gray, Richard A.
Publicado 2023

Comprehensive Uncertainty Quantification and Sensitivity Analysis for Cardiac Action Potential Models

por Pathmanathan, Pras, Cordeiro, Jonathan M., Gray, Richard A.
Publicado 2019

Implementation of Contraction to Electrophysiological Ventricular Myocyte Models, and Their Quantitative Characterization via Post-Extrasystolic Potentiation

por Ji, Yanyan Claire, Gray, Richard A., Fenton, Flavio H.
Publicado 2015

Cardiac strength-interval curves calculated using a bidomain tissue with a parsimonious ionic current

por Galappaththige, Suran K., Gray, Richard A., Roth, Bradley J.
Publicado 2017

Effect of Heart Structure on Ventricular Fibrillation in the Rabbit: A Simulation Study

por Galappaththige, Suran K., Pathmanathan, Pras, Bishop, Martin J., Gray, Richard A.
Publicado 2019

Credibility assessment of patient-specific computational modeling using patient-specific cardiac modeling as an exemplar

por Galappaththige, Suran, Gray, Richard A., Costa, Caroline Mendonca, Niederer, Steven, Pathmanathan, Pras
Publicado 2022

Acute effects of nonexcitatory electrical stimulation during systole in isolated cardiac myocytes and perfused heart

por Blinova, Ksenia, Stohlman, Jayna, Krauthamer, Victor, Knapton, Alan, Bloomquist, Erik, Gray, Richard A.
Publicado 2014

Uncertainty and variability in computational and mathematical models of cardiac physiology

por Mirams, Gary R., Pathmanathan, Pras, Gray, Richard A., Challenor, Peter, Clayton, Richard H.
Publicado 2016

Data-Driven Uncertainty Quantification for Cardiac Electrophysiological Models: Impact of Physiological Variability on Action Potential and Spiral Wave Dynamics

por Pathmanathan, Pras, Galappaththige, Suran K., Cordeiro, Jonathan M., Kaboudian, Abouzar, Fenton, Flavio H., Gray, Richard A.
Publicado 2020

Design and execution of a verification, validation, and uncertainty quantification plan for a numerical model of left ventricular flow after LVAD implantation

por Santiago, Alfonso, Butakoff, Constantine, Eguzkitza, Beatriz, Gray, Richard A., May-Newman, Karen, Pathmanathan, Pras, Vu, Vi, Vázquez, Mariano
Publicado 2022

Credibility Evidence for Computational Patient Models Used in the Development of Physiological Closed-Loop Controlled Devices for Critical Care Medicine

por Parvinian, Bahram, Pathmanathan, Pras, Daluwatte, Chathuri, Yaghouby, Farid, Gray, Richard A., Weininger, Sandy, Morrison, Tina M., Scully, Christopher G.
Publicado 2019

Simultaneous Quantification of Spatially Discordant Alternans in Voltage and Intracellular Calcium in Langendorff-Perfused Rabbit Hearts and Inconsistencies with Models of Cardiac...

por Uzelac, Ilija, Ji, Yanyan C., Hornung, Daniel, Schröder-Scheteling, Johannes, Luther, Stefan, Gray, Richard A., Cherry, Elizabeth M., Fenton, Flavio H.
Publicado 2017