Human engineered cardiac tissue model of hypertrophic cardiomyopathy recapitulates key hallmarks of the disease and the effect of chronic mavacamten treatment

por Wang, Kai, Schriver, Brian J., Aschar-Sobbi, Roozbeh, Yi, Alex Y., Feric, Nicole T., Graziano, Michael P.
Publicado 2023

Acute effects of cardiac contractility modulation stimulation in conventional 2D and 3D human induced pluripotent stem cell-derived cardiomyocyte models

por Feaster, Tromondae K., Feric, Nicole, Pallotta, Isabella, Narkar, Akshay, Casciola, Maura, Graziano, Michael P., Aschar-Sobbi, Roozbeh, Blinova, Ksenia
Publicado 2022

Engineered Cardiac Tissues Generated in the Biowire II: A Platform for Human-Based Drug Discovery

por Feric, Nicole T, Pallotta, Isabella, Singh, Rishabh, Bogdanowicz, Danielle R, Gustilo, Marietta M, Chaudhary, Khuram W, Willette, Robert N, Chendrimada, Tim P, Xu, Xiaoping, Graziano, Michael P, Aschar-Sobbi, Roozbeh
Publicado 2019

Activin A directly impairs human cardiomyocyte contractile function indicating a potential role in heart failure development

por MacDonnell, Scott, Megna, Jake, Ruan, Qin, Zhu, Olivia, Halasz, Gabor, Jasewicz, Dan, Powers, Kristi, E, Hock, del Pilar Molina-Portela, Maria, Jin, Ximei, Zhang, Dongqin, Torello, Justin, Feric, Nicole T., Graziano, Michael P., Shekhar, Akshay, Dunn, Michael E., Glass, David, Morton, Lori
Publicado 2022