The A9 dopamine neuron component in grafts of ventral mesencephalon is an important determinant for recovery of motor function in a rat model of Parkinson’s disease

por Grealish, Shane, Jönsson, Marie E., Li, Meng, Kirik, Deniz, Björklund, Anders, Thompson, Lachlan H.
Publicado 2010

In Vivo Reprogramming of Striatal NG2 Glia into Functional Neurons that Integrate into Local Host Circuitry

por Torper, Olof, Ottosson, Daniella Rylander, Pereira, Maria, Lau, Shong, Cardoso, Tiago, Grealish, Shane, Parmar, Malin
Publicado 2015

Highly efficient generation of induced neurons from human fibroblasts that survive transplantation into the adult rat brain

por Pereira, Maria, Pfisterer, Ulrich, Rylander, Daniella, Torper, Olof, Lau, Shong, Lundblad, Martin, Grealish, Shane, Parmar, Malin
Publicado 2014

Monosynaptic Tracing using Modified Rabies Virus Reveals Early and Extensive Circuit Integration of Human Embryonic Stem Cell-Derived Neurons

por Grealish, Shane, Heuer, Andreas, Cardoso, Tiago, Kirkeby, Agnete, Jönsson, Marie, Johansson, Jenny, Björklund, Anders, Jakobsson, Johan, Parmar, Malin
Publicado 2015

Target‐specific forebrain projections and appropriate synaptic inputs of hESC‐derived dopamine neurons grafted to the midbrain of parkinsonian rats

por Cardoso, Tiago, Adler, Andrew F., Mattsson, Bengt, Hoban, Deirdre B., Nolbrant, Sara, Wahlestedt, Jenny Nelander, Kirkeby, Agnete, Grealish, Shane, Björklund, Anders, Parmar, Malin
Publicado 2018

hESC-Derived Dopaminergic Transplants Integrate into Basal Ganglia Circuitry in a Preclinical Model of Parkinson’s Disease

por Adler, Andrew F., Cardoso, Tiago, Nolbrant, Sara, Mattsson, Bengt, Hoban, Deirdre B., Jarl, Ulla, Wahlestedt, Jenny Nelander, Grealish, Shane, Björklund, Anders, Parmar, Malin
Publicado 2019

Human ESC-Derived Dopamine Neurons Show Similar Preclinical Efficacy and Potency to Fetal Neurons when Grafted in a Rat Model of Parkinson’s Disease

por Grealish, Shane, Diguet, Elsa, Kirkeby, Agnete, Mattsson, Bengt, Heuer, Andreas, Bramoulle, Yann, Van Camp, Nadja, Perrier, Anselme L., Hantraye, Philippe, Björklund, Anders, Parmar, Malin
Publicado 2014

IAP-Based Cell Sorting Results in Homogeneous Transplantable Dopaminergic Precursor Cells Derived from Human Pluripotent Stem Cells

por Lehnen, Daniela, Barral, Serena, Cardoso, Tiago, Grealish, Shane, Heuer, Andreas, Smiyakin, Andrej, Kirkeby, Agnete, Kollet, Jutta, Cremer, Harold, Parmar, Malin, Bosio, Andreas, Knöbel, Sebastian
Publicado 2017

Predictive Markers Guide Differentiation to Improve Graft Outcome in Clinical Translation of hESC-Based Therapy for Parkinson’s Disease

por Kirkeby, Agnete, Nolbrant, Sara, Tiklova, Katarina, Heuer, Andreas, Kee, Nigel, Cardoso, Tiago, Ottosson, Daniella Rylander, Lelos, Mariah J., Rifes, Pedro, Dunnett, Stephen B., Grealish, Shane, Perlmann, Thomas, Parmar, Malin
Publicado 2017