DRP-1 is required for BH3 mimetic-mediated mitochondrial fragmentation and apoptosis

por Milani, Mateus, Byrne, Dominic P, Greaves, Georgia, Butterworth, Michael, Cohen, Gerald M, Eyers, Patrick A, Varadarajan, Shankar
Publicado 2017

Targeting intermediary metabolism enhances the efficacy of BH3 mimetic therapy in hematologic malignancies

por Al-Zebeeby, Aoula, Vogler, Meike, Milani, Mateus, Richards, Caitlin, Alotibi, Ahoud, Greaves, Georgia, Dyer, Martin J.S., Cohen, Gerald M., Varadarajan, Shankar
Publicado 2019

BH3-only proteins are dispensable for apoptosis induced by pharmacological inhibition of both MCL-1 and BCL-X(L)

por Greaves, Georgia, Milani, Mateus, Butterworth, Michael, Carter, Rachel J., Byrne, Dominic P., Eyers, Patrick A., Luo, Xu, Cohen, Gerald M., Varadarajan, Shankar
Publicado 2018

Exploring the potential of BH3 mimetic therapy in squamous cell carcinoma of the head and neck

por Carter, Rachel J., Milani, Mateus, Butterworth, Michael, Alotibi, Ahoud, Harper, Nicholas, Yedida, Govindaraju, Greaves, Georgia, Al-Zebeeby, Aoula, Jorgensen, Andrea L., Schache, Andrew G., Risk, Janet M., Shaw, Richard J., Jones, Terry M., Sacco, Joseph J., Hurlstone, Adam, Cohen, Gerald M., Varadarajan, Shankar
Publicado 2019