Chemo‐Enzymatic Synthesis of Pyrazines and Pyrroles

por Xu, Jin, Green, Anthony P., Turner, Nicholas J.
Publicado 2018

Chiral Amine Synthesis Using ω-Transaminases: An Amine Donor that Displaces Equilibria and Enables High-Throughput Screening**

por Green, Anthony P, Turner, Nicholas J, O'Reilly, Elaine
Publicado 2014

Engineering enzyme activity using an expanded amino acid alphabet

por Birch-Price, Zachary, Taylor, Christopher J, Ortmayer, Mary, Green, Anthony P
Publicado 2022

How Does Replacement of the Axial Histidine Ligand in Cytochrome c Peroxidase by N(δ)-Methyl Histidine Affect Its Properties and Functions? A Computational Study

por Lee, Calvin W. Z., Mubarak, M. Qadri E., Green, Anthony P., de Visser, Sam P.
Publicado 2020

Design of Heme Enzymes with a Tunable Substrate Binding Pocket Adjacent to an Open Metal Coordination Site

por Kalvet, Indrek, Ortmayer, Mary, Zhao, Jingming, Crawshaw, Rebecca, Ennist, Nathan M., Levy, Colin, Roy, Anindya, Green, Anthony P., Baker, David
Publicado 2023

Engineering mutually orthogonal PylRS/tRNA pairs for dual encoding of functional histidine analogues

por Taylor, Christopher J., Hardy, Florence J., Burke, Ashleigh J., Bednar, Riley M., Mehl, Ryan A., Green, Anthony P., Lovelock, Sarah L.
Publicado 2023

Insights into the H(2)O(2)‐driven catalytic mechanism of fungal lytic polysaccharide monooxygenases

por Hedison, Tobias M., Breslmayr, Erik, Shanmugam, Muralidharan, Karnpakdee, Kwankao, Heyes, Derren J., Green, Anthony P., Ludwig, Roland, Scrutton, Nigel S., Kracher, Daniel
Publicado 2021

Engineering an Efficient and Enantioselective Enzyme for the Morita-Baylis-Hillman Reaction

por Crawshaw, Rebecca, Crossley, Amy E., Johannissen, Linus, Burke, Ashleigh J., Hay, Sam, Levy, Colin, Baker, David, Lovelock, Sarah L., Green, Anthony P.
Publicado 2022

Multicomponent Synthesis of the SARS-CoV-2 Main Protease Inhibitor Nirmatrelvir

por Preschel, H. Daniel, Otte, Ruben T., Zhuo, Ying, Ruscoe, Rebecca E., Burke, Ashleigh J., Kellerhals, Rachel, Horst, Brendan, Hennig, Sven, Janssen, Elwin, Green, Anthony P., Turner, Nicholas J., Ruijter, Eelco
Publicado 2023

A promiscuous glycosyltransferase generates poly-β-1,4-glucan derivatives that facilitate mass spectrometry-based detection of cellulolytic enzymes

por Bulmer, Gregory S., Mattey, Ashley P., Parmeggiani, Fabio, Williams, Ryan, Ledru, Helene, Marchesi, Andrea, Seibt, Lisa S., Both, Peter, Huang, Kun, Galan, M. Carmen, Flitsch, Sabine L., Green, Anthony P., van Munster, Jolanda M.
Publicado 2021

A Noncanonical Tryptophan Analogue Reveals an Active Site Hydrogen Bond Controlling Ferryl Reactivity in a Heme Peroxidase

por Ortmayer, Mary, Hardy, Florence J., Quesne, Matthew G., Fisher, Karl, Levy, Colin, Heyes, Derren J., Catlow, C. Richard A., de Visser, Sam P., Rigby, Stephen E. J., Hay, Sam, Green, Anthony P.
Publicado 2021

Rewiring the “Push-Pull” Catalytic Machinery of a Heme Enzyme Using an Expanded Genetic Code

por Ortmayer, Mary, Fisher, Karl, Basran, Jaswir, Wolde-Michael, Emmanuel M., Heyes, Derren J., Levy, Colin, Lovelock, Sarah L., Anderson, J. L. Ross, Raven, Emma L., Hay, Sam, Rigby, Stephen E. J., Green, Anthony P.
Publicado 2020

An Engineered Cytidine Deaminase for Biocatalytic Production of a Key Intermediate of the Covid-19 Antiviral Molnupiravir

por Burke, Ashleigh J., Birmingham, William R., Zhuo, Ying, Thorpe, Thomas W., Zucoloto da Costa, Bruna, Crawshaw, Rebecca, Rowles, Ian, Finnigan, James D., Young, Carl, Holgate, Gregory M., Muldowney, Mark P., Charnock, Simon J., Lovelock, Sarah L., Turner, Nicholas J., Green, Anthony P.
Publicado 2022

Mapping the Initial Stages of a Protective Pathway that Enhances Catalytic Turnover by a Lytic Polysaccharide Monooxygenase

por Zhao, Jingming, Zhuo, Ying, Diaz, Daniel E., Shanmugam, Muralidharan, Telfer, Abbey J., Lindley, Peter J., Kracher, Daniel, Hayashi, Takahiro, Seibt, Lisa S., Hardy, Florence J., Manners, Oliver, Hedison, Tobias M., Hollywood, Katherine A., Spiess, Reynard, Cain, Kathleen M., Diaz-Moreno, Sofia, Scrutton, Nigel S., Tovborg, Morten, Walton, Paul H., Heyes, Derren J., Green, Anthony P.
Publicado 2023