Significant roadblocks exist in developing sputum sample libraries for clinical validation of novel in vitro diagnostics

por Dollow, Joshua M, Green, Justin A
Publicado 2014

In an in vitro model of human tuberculosis, monocyte-microglial networks regulate matrix metalloproteinase-1 and -3 gene expression and secretion via a p38 mitogen activated protei...

por Green, Justin A, Rand, Lucinda, Moores, Rachel, Dholakia, Shruti, Pezas, Theodore, Elkington, Paul T, Friedland, Jon S
Publicado 2013

Population Pharmacokinetics of Tafenoquine, a Novel Antimalarial

por Thakkar, Nilay, Green, Justin A., Koh, Gavin C. K. W., Duparc, Stephan, Tenero, David, Goyal, Navin
Publicado 2018

Mycobacterium tuberculosis-infected human monocytes down-regulate microglial MMP-2 secretion in CNS tuberculosis via TNFα, NFκB, p38 and caspase 8 dependent pathways

por Green, Justin A, Dholakia, Shruti, Janczar, Karolina, Ong, Catherine WM, Moores, Rachel, Fry, Julie, Elkington, Paul T, Roncaroli, Federico, Friedland, Jon S
Publicado 2011

Severe Acute Respiratory Syndrome (SARS) in Singapore: Clinical Features of Index Patient and Initial Contacts

por Hsu, Li-Yang, Lee, Cheng-Chuan, Green, Justin A., Ang, Brenda, Paton, Nicholas I., Lee, Lawrence, Villacian, Jorge S., Lim, Poh-Lian, Earnest, Arul, Leo, Yee-Sin
Publicado 2003

Tafenoquine at therapeutic concentrations does not prolong fridericia-corrected QT interval in healthy subjects

por Green, Justin A, Patel, Apurva K, Patel, Bela R, Hussaini, Azra, Harrell, Emma J, McDonald, Mirna J, Carter, Nick, Mohamed, Khadeeja, Duparc, Stephan, Miller, Ann K
Publicado 2014

Pharmacokinetic Interactions between Tafenoquine and Dihydroartemisinin-Piperaquine or Artemether-Lumefantrine in Healthy Adult Subjects

por Green, Justin A., Mohamed, Khadeeja, Goyal, Navin, Bouhired, Samia, Hussaini, Azra, Jones, Siôn W., Koh, Gavin C. K. W., Kostov, Ivan, Taylor, Maxine, Wolstenholm, Allen, Duparc, Stephan
Publicado 2016

A randomized, double-blind, active-control trial to evaluate the efficacy and safety of a three day course of tafenoquine monotherapy for the treatment of Plasmodium vivax malaria

por Fukuda, Mark M., Krudsood, Srivicha, Mohamed, Khadeeja, Green, Justin A., Warrasak, Sukhuma, Noedl, Harald, Euswas, Ataya, Ittiverakul, Mali, Buathong, Nillawan, Sriwichai, Sabaithip, Miller, R. Scott, Ohrt, Colin
Publicado 2017

Estimation of the Antirelapse Efficacy of Tafenoquine, Using Plasmodium vivax Genotyping

por Beck, Hans-Peter, Wampfler, Rahel, Carter, Nick, Koh, Gavin, Osorio, Lyda, Rueangweerayut, Ronnatrai, Krudsood, Srivcha, Lacerda, Marcus V., Llanos-Cuentas, Alejandro, Duparc, Stephan, Rubio, Justin P., Green, Justin A.
Publicado 2016

Dexamethasone, Cerebrospinal Fluid Matrix Metalloproteinase Concentrations and Clinical Outcomes in Tuberculous Meningitis

por Green, Justin A., Tran, Chau T. H., Farrar, Jeremy J., Nguyen, Mai T. H., Nguyen, Phu H., Dinh, Sinh X., Ho, Nghia D. T., Ly, Chuong V., Tran, Hien T., Friedland, Jon S., Thwaites, Guy E.
Publicado 2009

Tafenoquine treatment of Plasmodium vivax malaria: suggestive evidence that CYP2D6 reduced metabolism is not associated with relapse in the Phase 2b DETECTIVE trial

por St Jean, Pamela L., Xue, Zhengyu, Carter, Nick, Koh, Gavin C. K. W., Duparc, Stephan, Taylor, Maxine, Beaumont, Claire, Llanos-Cuentas, Alejandro, Rueangweerayut, Ronnatrai, Krudsood, Srivicha, Green, Justin A., Rubio, Justin P.
Publicado 2016

The clinical pharmacology of tafenoquine in the radical cure of Plasmodium vivax malaria: An individual patient data meta-analysis

por Watson, James A, Commons, Robert J, Tarning, Joel, Simpson, Julie A, Llanos Cuentas, Alejandro, Lacerda, Marcus VG, Green, Justin A, Koh, Gavin CKW, Chu, Cindy S, Nosten, François H, Price, Richard N, Day, Nicholas PJ, White, Nicholas J
Publicado 2022

Hemolytic Potential of Tafenoquine in Female Volunteers Heterozygous for Glucose-6-Phosphate Dehydrogenase (G6PD) Deficiency (G6PD Mahidol Variant) versus G6PD-Normal Volunteers

por Rueangweerayut, Ronnatrai, Bancone, Germana, Harrell, Emma J., Beelen, Andrew P., Kongpatanakul, Supornchai, Möhrle, Jörg J., Rousell, Vicki, Mohamed, Khadeeja, Qureshi, Ammar, Narayan, Sushma, Yubon, Nushara, Miller, Ann, Nosten, François H., Luzzatto, Lucio, Duparc, Stephan, Kleim, Jörg-Peter, Green, Justin A.
Publicado 2017

Provider and household costs of Plasmodium vivax malaria episodes: a multicountry comparative analysis of primary trial data

por Devine, Angela, Pasaribu, Ayodhia P, Teferi, Tedlla, Pham, Huong-Thu, Awab, Ghulam Rahim, Contantia, Febrina, Nguyen, Thuy-Nhien, Ngo, Viet-Thanh, Tran, Tinh-Hien, Hailu, Asrat, Gilchrist, Kim, Green, Justin A, Koh, Gavin CKW, Thriemer, Kamala, Taylor, Walter RJ, Day, Nicholas PJ, Price, Ric N, Lubell, Yoel
Publicado 2019

Pharmacogenetic assessment of tafenoquine efficacy in patients with Plasmodium vivax malaria

por St Jean, Pamela L., Koh, Gavin C.K.W., Breton, John J., Espino, Fe E.J., Hien, Tran T., Krudsood, Srivicha, Lacerda, Marcus V.G., Llanos-Cuentas, Alejandro, Lon, Chanthap, Mohammed, Rezika, Namaik-larp, Chayadol S., Pereira, Dhelio B., Saunders, David L., Velez, Ivan D., Yilma, Daniel, Villegas, Maria F., Duparc, Stephan, Green, Justin A.
Publicado 2020

Tolerability and immunogenicity of an intranasally-administered adenovirus-vectored COVID-19 vaccine: An open-label partially-randomised ascending dose phase I trial

por Madhavan, Meera, Ritchie, Adam J., Aboagye, Jeremy, Jenkin, Daniel, Provstgaad-Morys, Samuel, Tarbet, Iona, Woods, Danielle, Davies, Sophie, Baker, Megan, Platt, Abigail, Flaxman, Amy, Smith, Holly, Belij-Rammerstorfer, Sandra, Wilkins, Deidre, Kelly, Elizabeth J., Villafana, Tonya, Green, Justin A., Poulton, Ian, Lambe, Teresa, Hill, Adrian V.S., Ewer, Katie J., Douglas, Alexander D.
Publicado 2022

Lineage-informative microhaplotypes for spatio-temporal surveillance of Plasmodium vivax malaria parasites

por Siegel, Sasha V., Amato, Roberto, Trimarsanto, Hidayat, Sutanto, Edwin, Kleinecke, Mariana, Murie, Kathryn, Whitton, Georgia, Taylor, Aimee R., Watson, James A., Imwong, Mallika, Assefa, Ashenafi, Rahim, Awab Ghulam, Chau, Nguyen Hoang, Hien, Tran Tinh, Green, Justin A, Koh, Gavin, White, Nicholas J., Day, Nicholas, Kwiatkowski, Dominic P., Rayner, Julian C., Price, Ric N., Auburn, Sarah
Publicado 2023

Randomized Placebo-Controlled Trial Evaluating the Ophthalmic Safety of Single-Dose Tafenoquine in Healthy Volunteers

por Ackert, Jessica, Mohamed, Khadeeja, Slakter, Jason S., El-Harazi, Sherif, Berni, Alessandro, Gevorkyan, Hakop, Hardaker, Elizabeth, Hussaini, Azra, Jones, Siôn W., Koh, Gavin C. K. W., Patel, Jyoti, Rasmussen, Scott, Kelly, Deborah S., Barañano, David E., Thompson, John T., Warren, Keith A., Sergott, Robert C., Tonkyn, John, Wolstenholme, Allen, Coleman, Hanna, Yuan, Alex, Duparc, Stephan, Green, Justin A.
Publicado 2019

Durability of protection and immunogenicity of AZD1222 (ChAdOx1 nCoV-19) COVID-19 vaccine over 6 months

por Sobieszczyk, Magdalena E., Maaske, Jill, Falsey, Ann R., Sproule, Stephanie, Robb, Merlin L., Frenck, Robert W., Tieu, Hong-Van, Mayer, Kenneth H., Corey, Lawrence, Neuzil, Kathleen M., Tong, Tina, Brewinski Isaacs, Margaret, Janes, Holly, Bansal, Himanshu, Edwards, Lindsay M., Green, Justin A., Kelly, Elizabeth J., Shoemaker, Kathryn, Takas, Therese, White, Tom, Bhuyan, Prakash, Villafana, Tonya, Hirsch, and Ian
Publicado 2022

Robust humoral and cellular recall responses to AZD1222 attenuate breakthrough SARS-CoV-2 infection compared to unvaccinated

por Maaske, Jill, Sproule, Stephanie, Falsey, Ann R., Sobieszczyk, Magdalena E., Luetkemeyer, Anne F., Paulsen, Grant C., Riddler, Sharon A., Robb, Merlin L., Rolle, Charlotte-Paige, Sha, Beverly E., Tong, Tina, Ahani, Bahar, Aksyuk, Anastasia A., Bansal, Himanshu, Egan, Timothy, Jepson, Brett, Padilla, Marcelino, Patel, Nirmeshkumar, Shoemaker, Kathryn, Stanley, Ann Marie, Swanson, Phillip A., Wilkins, Deidre, Villafana, Tonya, Green, Justin A., Kelly, Elizabeth J.
Publicado 2023