Casein kinase 1 delta functions at the centrosome to mediate Wnt-3a–dependent neurite outgrowth

por Greer, Yoshimi Endo, Rubin, Jeffrey S.
Publicado 2011

TIC10/ONC201: a bend in the road to clinical development

por Greer, Yoshimi Endo, Lipkowitz, Stanley
Publicado 2015

Novel Apoptosis-Inducing Agents for the Treatment of Cancer, a New Arsenal in the Toolbox

por Lim, Bora, Greer, Yoshimi, Lipkowitz, Stanley, Takebe, Naoko
Publicado 2019

Targeting TRAIL Death Receptors in Triple-Negative Breast Cancers: Challenges and Strategies for Cancer Therapy

por Kundu, Manjari, Greer, Yoshimi Endo, Dine, Jennifer L., Lipkowitz, Stanley
Publicado 2022

Lack of Casein Kinase 1 Delta Promotes Genomic Instability - The Accumulation of DNA Damage and Down-Regulation of Checkpoint Kinase 1

por Greer, Yoshimi Endo, Gao, Bo, Yang, Yingzi, Nussenzweig, Andre, Rubin, Jeffrey S.
Publicado 2017

Targeting Mitochondria with ClpP Agonists as a Novel Therapeutic Opportunity in Breast Cancer

por Wedam, Rohan, Greer, Yoshimi Endo, Wisniewski, David J., Weltz, Sarah, Kundu, Manjari, Voeller, Donna, Lipkowitz, Stanley
Publicado 2023

MEDI3039, a novel highly potent tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) receptor 2 agonist, causes regression of orthotopic tumors and inhibits outgro...

por Greer, Yoshimi Endo, Gilbert, Samuel F., Gril, Brunilde, Narwal, Rajesh, Peacock Brooks, Danielle L., Tice, David A., Steeg, Patricia S., Lipkowitz, Stanley
Publicado 2019

Casein kinase 1δ functions at the centrosome and Golgi to promote ciliogenesis

por Greer, Yoshimi Endo, Westlake, Christopher J., Gao, Bo, Bharti, Kapil, Shiba, Yoko, Xavier, Charles P., Pazour, Gregory J., Yang, Yingzi, Rubin, Jeffrey S.
Publicado 2014

Multi-omics analyses reveal ClpP activators disrupt essential mitochondrial pathways in triple-negative breast cancer

por Fennell, Emily M. J., Aponte-Collazo, Lucas J., Pathmasiri, Wimal, Rushing, Blake R., Barker, Natalie K., Partridge, Megan C., Li, Yuan-Yuan, White, Cody A., Greer, Yoshimi E., Herring, Laura E., Lipkowitz, Stanley, Sumner, Susan C. J., Iwanowicz, Edwin J., Graves, Lee M.
Publicado 2023

Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

por Greer, Yoshimi Endo, Hernandez, Lidia, Fennell, Emily M.J., Kundu, Manjari, Voeller, Donna, Chari, Raj, Gilbert, Samuel F., Gilbert, Thomas S.K., Ratnayake, Shashikala, Tang, Binwu, Hafner, Markus, Chen, Qingrong, Meerzaman, Daoud, Iwanowicz, Edwin, Annunziata, Christina M., Graves, Lee M., Lipkowitz, Stanley
Publicado 2022

Characterization of TR‐107, a novel chemical activator of the human mitochondrial protease ClpP

por Fennell, Emily M. J., Aponte‐Collazo, Lucas J., Wynn, Joshua D., Drizyte‐Miller, Kristina, Leung, Elisa, Greer, Yoshimi Endo, Graves, Paul R., Iwanowicz, Andrew A., Ashamalla, Hani, Holmuhamedov, Ekhson, Lang, Henk, Karanewsky, Donald S., Der, Channing J., Houry, Walid A., Lipkowitz, Stanley, Iwanowicz, Edwin J., Graves, Lee M.
Publicado 2022

ONC201 kills breast cancer cells in vitro by targeting mitochondria

por Greer, Yoshimi Endo, Porat-Shliom, Natalie, Nagashima, Kunio, Stuelten, Christina, Crooks, Dan, Koparde, Vishal N., Gilbert, Samuel F., Islam, Celia, Ubaldini, Ashley, Ji, Yun, Gattinoni, Luca, Soheilian, Ferri, Wang, Xiantao, Hafner, Markus, Shetty, Jyoti, Tran, Bao, Jailwala, Parthav, Cam, Maggie, Lang, Martin, Voeller, Donna, Reinhold, William C., Rajapakse, Vinodh, Pommier, Yves, Weigert, Roberto, Linehan, W. Marston, Lipkowitz, Stanley
Publicado 2018