Fan1 deficiency results in DNA interstrand cross-link repair defects, enhanced tissue karyomegaly, and organ dysfunction

por Thongthip, Supawat, Bellani, Marina, Gregg, Siobhan Q., Sridhar, Sunandini, Conti, Brooke A., Chen, Yanglu, Seidman, Michael M., Smogorzewska, Agata
Publicado 2016

Identification of HSP90 inhibitors as a novel class of senolytics

por Fuhrmann-Stroissnigg, Heike, Ling, Yuan Yuan, Zhao, Jing, McGowan, Sara J., Zhu, Yi, Brooks, Robert W., Grassi, Diego, Gregg, Siobhan Q., Stripay, Jennifer L., Dorronsoro, Akaitz, Corbo, Lana, Tang, Priscilla, Bukata, Christina, Ring, Nadja, Giacca, Mauro, Li, Xuesen, Tchkonia, Tamara, Kirkland, James L., Niedernhofer, Laura J., Robbins, Paul D.
Publicado 2017

Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging

por Robinson, Andria R., Yousefzadeh, Matthew J., Rozgaja, Tania A., Wang, Jin, Li, Xuesen, Tilstra, Jeremy S., Feldman, Chelsea H., Gregg, Siobhán Q., Johnson, Caroline H., Skoda, Erin M., Frantz, Marie-Céline, Bell-Temin, Harris, Pope-Varsalona, Hannah, Gurkar, Aditi U., Nasto, Luigi A., Robinson, Renã A.S., Fuhrmann-Stroissnigg, Heike, Czerwinska, Jolanta, McGowan, Sara J., Cantu-Medellin, Nadiezhda, Harris, Jamie B., Maniar, Salony, Ross, Mark A., Trussoni, Christy E., LaRusso, Nicholas F., Cifuentes-Pagano, Eugenia, Pagano, Patrick J., Tudek, Barbara, Vo, Nam V., Rigatti, Lora H., Opresko, Patricia L., Stolz, Donna B., Watkins, Simon C., Burd, Christin E., Croix, Claudette M. St., Siuzdak, Gary, Yates, Nathan A., Robbins, Paul D., Wang, Yinsheng, Wipf, Peter, Kelley, Eric E., Niedernhofer, Laura J.
Publicado 2018