SR Protein Kinases Regulate the Splicing of Cardiomyopathy-Relevant Genes via Phosphorylation of the RSRSP Stretch in RBM20

por Sun, Mingming, Jin, Yutong, Zhang, Yanghai, Gregorich, Zachery R, Ren, Jun, Ge, Ying, Guo, Wei
Publicado 2022

Deletion of Enigma Homologue from the Z-disc slows tension development kinetics in mouse myocardium

por Gregorich, Zachery R., Patel, Jitandrakumar R., Cai, Wenxuan, Lin, Ziqing, Heurer, Rachel, Fitzsimons, Daniel P., Moss, Richard L., Ge, Ying
Publicado 2019

Disruption of the nuclear localization signal in RBM20 is causative in dilated cardiomyopathy

por Zhang, Yanghai, Gregorich, Zachery R., Wang, Yujuan, Braz, Camila Urbano, Zhang, Jibin, Liu, Yang, Liu, Peiheng, Shen, Jiaxi, Aori, Nanyumuzi, Hacker, Timothy A., Granzier, Henk, Guo, Wei
Publicado 2023

Cardiac differentiation of human pluripotent stem cells using defined extracellular matrix proteins reveals essential role of fibronectin

por Zhang, Jianhua, Gregorich, Zachery R, Tao, Ran, Kim, Gina C, Lalit, Pratik A, Carvalho, Juliana L, Markandeya, Yogananda, Mosher, Deane F, Palecek, Sean P, Kamp, Timothy J
Publicado 2022

Top-down Proteomics Reveals Concerted Reductions in Myofilament and Z-disc Protein Phosphorylation after Acute Myocardial Infarction

por Peng, Ying, Gregorich, Zachery R., Valeja, Santosh G., Zhang, Han, Cai, Wenxuan, Chen, Yi-Chen, Guner, Huseyin, Chen, Albert J., Schwahn, Denise J., Hacker, Timothy A., Liu, Xiaowen, Ge, Ying
Publicado 2014

High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms

por Melby, Jake A., Brown, Kyle A., Gregorich, Zachery R., Roberts, David S., Chapman, Emily A., Ehlers, Lauren E., Gao, Zhan, Larson, Eli J., Jin, Yutong, Lopez, Justin R., Hartung, Jared, Zhu, Yanlong, McIlwain, Sean J., Wang, Daojing, Guo, Wei, Diffee, Gary M., Ge, Ying
Publicado 2023

Distinct hypertrophic cardiomyopathy genotypes result in convergent sarcomeric proteoform profiles revealed by top-down proteomics

por Tucholski, Trisha, Cai, Wenxuan, Gregorich, Zachery R., Bayne, Elizabeth F., Mitchell, Stanford D., McIlwain, Sean J., de Lange, Willem J., Wrobbel, Max, Karp, Hannah, Hite, Zachary, Vikhorev, Petr G., Marston, Steven B., Lal, Sean, Li, Amy, dos Remedios, Cristobal, Kohmoto, Takushi, Hermsen, Joshua, Ralphe, J. Carter, Kamp, Timothy J., Moss, Richard L., Ge, Ying
Publicado 2020