CAP2 is a regulator of actin pointed end dynamics and myofibrillogenesis in cardiac muscle

por Colpan, Mert, Iwanski, Jessika, Gregorio, Carol C.
Publicado 2021

Nebulin regulates actin filament lengths by a stabilization mechanism

por Pappas, Christopher T., Krieg, Paul A., Gregorio, Carol C.
Publicado 2010

Investigating lasp-2 in cell adhesion: new binding partners and roles in motility

por Bliss, Katherine T., Chu, Miensheng, Jones-Weinert, Colin M., Gregorio, Carol C.
Publicado 2013

Regulation of Heart Rate in Drosophila via Fragile X Mental Retardation Protein

por Novak, Stefanie Mares, Joardar, Archi, Gregorio, Carol C., Zarnescu, Daniela C.
Publicado 2015

Muscle-specific RING finger-1 interacts with titin to regulate sarcomeric M-line and thick filament structure and may have nuclear functions via its interaction with glucocorticoid...

por McElhinny, Abigail S., Kakinuma, Kazumi, Sorimachi, Hiroyuki, Labeit, Siegfried, Gregorio, Carol C.
Publicado 2002

Nebulin regulates the assembly and lengths of the thin filaments in striated muscle

por McElhinny, Abigail S., Schwach, Catherine, Valichnac, Melinda, Mount-Patrick, Sarah, Gregorio, Carol C.
Publicado 2005

The interaction of tropomodulin with tropomyosin stabilizes thin filaments in cardiac myocytes

por Mudry, Ryan E., Perry, Cynthia N., Richards, Meredith, Fowler, Velia M., Gregorio, Carol C.
Publicado 2003

I-Band Titin in Cardiac Muscle Is a Three-Element Molecular Spring and Is Critical for Maintaining Thin Filament Structure

por Linke, Wolfgang A., Rudy, Diane E., Centner, Thomas, Gautel, Mathias, Witt, Christian, Labeit, Siegfried, Gregorio, Carol C.
Publicado 1999

Ca(2+) attenuates nucleation activity of leiomodin

por Smith, Garry E., Tolkatchev, Dmitri, Risi, Cristina, Little, Madison, Gregorio, Carol C., Galkin, Vitold E., Kostyukova, Alla S.
Publicado 2022

In vivo elongation of thin filaments results in heart failure

por Mi-Mi, Lei, Farman, Gerrie P., Mayfield, Rachel M., Strom, Joshua, Chu, Miensheng, Pappas, Christopher T., Gregorio, Carol C.
Publicado 2020

Aberrant myofibril assembly in tropomodulin1 null mice leads to aborted heart development and embryonic lethality

por Fritz-Six, Kimberly L., Cox, Patrick R., Fischer, Robert S., Xu, Bisong, Gregorio, Carol C., Zoghbi, Huda Y., Fowler, Velia M.
Publicado 2003

Effects of cardiomyopathy-linked mutations K15N and R21H in tropomyosin on thin-filament regulation and pointed-end dynamics

por Ly, Thu, Pappas, Christopher T., Johnson, Dylan, Schlecht, William, Colpan, Mert, Galkin, Vitold E., Gregorio, Carol C., Dong, Wen-Ji, Kostyukova, Alla S.
Publicado 2019

Leiomodin creates a leaky cap at the pointed end of actin-thin filaments

por Tolkatchev, Dmitri, Smith, Garry E., Schultz, Lauren E., Colpan, Mert, Helms, Gregory L., Cort, John R., Gregorio, Carol C., Kostyukova, Alla S.
Publicado 2020

The N-terminal tropomyosin- and actin-binding sites are important for leiomodin 2’s function

por Ly, Thu, Moroz, Natalia, Pappas, Christopher T., Novak, Stefanie M., Tolkatchev, Dmitri, Wooldridge, Dayton, Mayfield, Rachel M., Helms, Gregory, Gregorio, Carol C., Kostyukova, Alla S.
Publicado 2016

The NH(2) Terminus of Titin Spans the Z-Disc: Its Interaction with a Novel 19-kD Ligand (T-cap) Is Required for Sarcomeric Integrity

por Gregorio, Carol C., Trombitás, Karoly, Centner, Thomas, Kolmerer, Bernhard, Stier, Gunter, Kunke, Kathleen, Suzuki, Koichi, Obermayr, Franz, Herrmann, Bernhard, Granzier, Henk, Sorimachi, Hiroyuki, Labeit, Siegfried
Publicado 1998

Myopalladin, a Novel 145-Kilodalton Sarcomeric Protein with Multiple Roles in Z-Disc and I-Band Protein Assemblies

por Bang, Marie-Louise, Mudry, Ryan E., McElhinny, Abigail S., Trombitás, Karoly, Geach, Adam J., Yamasaki, Rob, Sorimachi, Hiroyuki, Granzier, Henk, Gregorio, Carol C., Labeit, Siegfried
Publicado 2001

Neonatal-lethal dilated cardiomyopathy due to a homozygous LMOD2 donor splice-site variant

por Yuen, Michaela, Worgan, Lisa, Iwanski, Jessika, Pappas, Christopher T., Joshi, Himanshu, Churko, Jared M., Arbuckle, Susan, Kirk, Edwin P., Zhu, Ying, Roscioli, Tony, Gregorio, Carol C., Cooper, Sandra T.
Publicado 2022

Cardiac-enriched BAF chromatin-remodeling complex subunit Baf60c regulates gene expression programs essential for heart development and function

por Sun, Xin, Hota, Swetansu K., Zhou, Yu-Qing, Novak, Stefanie, Miguel-Perez, Dario, Christodoulou, Danos, Seidman, Christine E., Seidman, J. G., Gregorio, Carol C., Henkelman, R. Mark, Rossant, Janet, Bruneau, Benoit G.
Publicado 2017

Disruption of cardiac thin filament assembly arising from a mutation in LMOD2: A novel mechanism of neonatal dilated cardiomyopathy

por Ahrens-Nicklas, Rebecca C., Pappas, Christopher T., Farman, Gerrie P., Mayfield, Rachel M., Larrinaga, Tania M., Medne, Livija, Ritter, Alyssa, Krantz, Ian D., Murali, Chaya, Lin, Kimberly Y., Berger, Justin H., Yum, Sabrina W., Carreon, Chrystalle Katte, Gregorio, Carol C.
Publicado 2019

Antihypertensive drug treatment and susceptibility to SARS-CoV-2 infection in human PSC-derived cardiomyocytes and primary endothelial cells

por Iwanski, Jessika, Kazmouz, Sobhi G., Li, Shuaizhi, Stansfield, Ben, Salem, Tori T., Perez-Miller, Samantha, Kazui, Toshinobu, Jena, Lipsa, Uhrlaub, Jennifer L., Lick, Scott, Nikolich-Žugich, Janko, Konhilas, John P., Gregorio, Carol C., Khanna, May, Campos, Samuel K., Churko, Jared M.
Publicado 2021