ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing

por Breton, Camilo, Clark, Peter M., Wang, Lili, Greig, Jenny A., Wilson, James M.
Publicado 2020

Correction to: ITR-Seq, a next-generation sequencing assay, identifies genome-wide DNA editing sites in vivo following adeno-associated viral vector-mediated genome editing

por Breton, Camilo, Clark, Peter M., Wang, Lili, Greig, Jenny A., Wilson, James M.
Publicado 2020

Prevalent and Disseminated Recombinant and Wild-Type Adeno-Associated Virus Integration in Macaques and Humans

por Martins, Kelly M., Breton, Camilo, Zheng, Qi, Zhang, Zhe, Latshaw, Caitlin, Greig, Jenny A., Wilson, James M.
Publicado 2023

Impact of intravenous infusion time on AAV8 vector pharmacokinetics, safety, and liver transduction in cynomolgus macaques

por Greig, Jenny A, Nordin, Jayme ML, Bote, Erin, Makaron, Leah, Garnett, Mason E, Kattenhorn, Lisa M, Bell, Peter, Goode, Tamara, Wilson, James M
Publicado 2016

Determining the Minimally Effective Dose of a Clinical Candidate AAV Vector in a Mouse Model of Crigler-Najjar Syndrome

por Greig, Jenny A., Nordin, Jayme M.L., Draper, Christine, McMenamin, Deirdre, Chroscinski, Edward A., Bell, Peter, Gray, John T., Richman, Laura K., Wilson, James M.
Publicado 2018

Lipid nanoparticle-encapsulated mRNA therapy corrects serum total bilirubin level in Crigler-Najjar syndrome mouse model

por Greig, Jenny A., Chorazeczewski, Joanna K., Chowdhary, Vivek, Smith, Melanie K., Jennis, Matthew, Tarrant, James C., Buza, Elizabeth L., Coughlan, Kimberly, Martini, Paolo G.V., Wilson, James M.
Publicado 2023

Determining the Minimally Effective Dose of a Clinical Candidate Adeno-Associated Virus Vector in a Mouse Model of Hemophilia A

por Greig, Jenny A., Smith, Melanie K., Nordin, Jayme M.L., Goode, Tamara, Chroscinski, Edward A., Buza, Elizabeth L., Schmidt, Nicole, Kattenhorn, Lisa M., Wadsworth, Samuel, Wilson, James M.
Publicado 2022

Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors

por Horiuchi, Makoto, Hinderer, Christian J., Greig, Jenny A., Dyer, Cecilia, Buza, Elizabeth L., Bell, Peter, Chichester, Jessica A., Hayashi, Peter M., Yan, Hanying, Goode, Tamara, Wilson, James M.
Publicado 2022

Intravenous immunoglobulin prevents peripheral liver transduction of intrathecally delivered AAV vectors

por Horiuchi, Makoto, Hinderer, Christian J., Greig, Jenny A., Dyer, Cecilia, Buza, Elizabeth L., Bell, Peter, Chichester, Jessica A., Hayashi, Peter M., Yan, Hanying, Goode, Tamara, Wilson, James M.
Publicado 2022

Intramuscular Injection of AAV8 in Mice and Macaques Is Associated with Substantial Hepatic Targeting and Transgene Expression

por Greig, Jenny A., Peng, Hui, Ohlstein, Jason, Medina-Jaszek, C. Angelica, Ahonkhai, Omua, Mentzinger, Anne, Grant, Rebecca L., Roy, Soumitra, Chen, Shu-Jen, Bell, Peter, Tretiakova, Anna P., Wilson, James M.
Publicado 2014

AAV8 Gene Therapy for Crigler-Najjar Syndrome in Macaques Elicited Transgene T Cell Responses That Are Resident to the Liver

por Greig, Jenny A., Calcedo, Roberto, Kuri-Cervantes, Leticia, Nordin, Jayme M.L., Albrecht, Jessica, Bote, Erin, Goode, Tamara, Chroscinski, Edward A., Bell, Peter, Richman, Laura K., Betts, Michael R., Wilson, James M.
Publicado 2018

Intranasal gene therapy to prevent infection by SARS-CoV-2 variants

por Sims, Joshua J., Greig, Jenny A., Michalson, Kristofer T., Lian, Sharon, Martino, R. Alexander, Meggersee, Rosemary, Turner, Kevin B., Nambiar, Kalyani, Dyer, Cecilia, Hinderer, Christian, Horiuchi, Makoto, Yan, Hanying, Huang, Xin, Chen, Shu-Jen, Wilson, James M.
Publicado 2021

Treating Transthyretin Amyloidosis via Adeno-Associated Virus Vector Delivery of Meganucleases

por Greig, Jenny A., Breton, Camilo, Ashley, Scott N., Martins, Kelly M., Gorsuch, Cassandra, Chorazeczewski, Joanna K., Furmanak, Thomas, Smith, Melanie K., Zhu, Yanqing, Bell, Peter, Shoop, Wendy, Li, Hui, Smith, Jeff, Tomberlin, Ginger, Clark, Peter, Mitchell, Thomas W., Buza, Elizabeth L., Yan, Hanying, Jantz, Derek, Wilson, James M.
Publicado 2022