Probing the cancer genome

por Greulich, Heidi
Publicado 2008

Activating Mutations in ERBB2 and Their Impact on Diagnostics and Treatment

por Herter-Sprie, Grit S., Greulich, Heidi, Wong, Kwok-Kin
Publicado 2013

SNP panel identification assay (SPIA): a genetic-based assay for the identification of cell lines

por Demichelis, Francesca, Greulich, Heidi, Macoska, Jill A., Beroukhim, Rameen, Sellers, William R., Garraway, Levi, Rubin, Mark A.
Publicado 2008

Inhibitor-Sensitive FGFR1 Amplification in Human Non-Small Cell Lung Cancer

por Dutt, Amit, Ramos, Alex H., Hammerman, Peter S., Mermel, Craig, Cho, Jeonghee, Sharifnia, Tanaz, Chande, Ajit, Tanaka, Kumiko Elisa, Stransky, Nicolas, Greulich, Heidi, Gray, Nathanael S., Meyerson, Matthew
Publicado 2011

Oncogenic Transformation by Inhibitor-Sensitive and -Resistant EGFR Mutants

por Greulich, Heidi, Chen, Tzu-Hsiu, Feng, Whei, Jänne, Pasi A, Alvarez, James V, Zappaterra, Mauro, Bulmer, Sara E, Frank, David A, Hahn, William C, Sellers, William R, Meyerson, Matthew
Publicado 2005

Activating mutations in ALK provide a therapeutic target in neuroblastoma

por George, Rani E., Sanda, Takaomi, Hanna, Megan, Fröhling, Stefan, Luther, William, Zhang, Jianming, Ahn, Yebin, Zhou, Wenjun, London, Wendy B., McGrady, Patrick, Xue, Liquan, Zozulya, Sergey, Gregor, Vlad, Webb, Thomas R., Gray, Nathanael S., Gilliland, D. Gary, Diller, Lisa, Greulich, Heidi, Morris, Stephan W., Meyerson, Matthew, Look, A. Thomas
Publicado 2008

Colon cancer-derived oncogenic EGFR G724S mutant identified by whole genome sequence analysis is dependent on asymmetric dimerization and sensitive to cetuximab

por Cho, Jeonghee, Bass, Adam J, Lawrence, Michael S, Cibulskis, Kristian, Cho, Ahye, Lee, Shi-Nai, Yamauchi, Mai, Wagle, Nikhil, Pochanard, Panisa, Kim, Nayoung, Park, Angela KJ, Won, Jonghwa, Hur, Hyung-Suk, Greulich, Heidi, Ogino, Shuji, Sougnez, Carrie, Voet, Douglas, Tabernero, Josep, Jimenez, Jose, Baselga, Jose, Gabriel, Stacey B, Lander, Eric S, Getz, Gad, Eck, Michael J, Park, Woong-Yang, Meyerson, Matthew
Publicado 2014

Identification of cancer cytotoxic modulators of PDE3A by predictive chemogenomics

por de Waal, Luc, Lewis, Timothy A., Rees, Matthew G., Tsherniak, Aviad, Wu, Xiaoyun, Choi, Peter S., Gechijian, Lara, Hartigan, Christina, Faloon, Patrick W., Hickey, Mark J., Tolliday, Nicola, Carr, Steven A., Clemons, Paul A., Munoz, Benito, Wagner, Bridget K., Shamji, Alykhan F., Koehler, Angela N., Schenone, Monica, Burgin, Alex B., Schreiber, Stuart L., Greulich, Heidi, Meyerson, Matthew
Publicado 2015

Structure of PDE3A-SLFN12 complex reveals requirements for activation of SLFN12 RNase

por Garvie, Colin W., Wu, Xiaoyun, Papanastasiou, Malvina, Lee, Sooncheol, Fuller, James, Schnitzler, Gavin R., Horner, Steven W., Baker, Andrew, Zhang, Terry, Mullahoo, James P., Westlake, Lindsay, Hoyt, Stephanie H., Toetzl, Marcus, Ranaghan, Matthew J., de Waal, Luc, McGaunn, Joseph, Kaplan, Bethany, Piccioni, Federica, Yang, Xiaoping, Lange, Martin, Tersteegen, Adrian, Raymond, Donald, Lewis, Timothy A., Carr, Steven A., Cherniack, Andrew D., Lemke, Christopher T., Meyerson, Matthew, Greulich, Heidi
Publicado 2021

Epidermal Growth Factor Receptor Activation in Glioblastoma through Novel Missense Mutations in the Extracellular Domain

por Lee, Jeffrey C, Vivanco, Igor, Beroukhim, Rameen, Huang, Julie H. Y, Feng, Whei L, DeBiasi, Ralph M, Yoshimoto, Koji, King, Jennifer C, Nghiemphu, Phioanh, Yuza, Yuki, Xu, Qing, Greulich, Heidi, Thomas, Roman K, Paez, J. Guillermo, Peck, Timothy C, Linhart, David J, Glatt, Karen A, Getz, Gad, Onofrio, Robert, Ziaugra, Liuda, Levine, Ross L, Gabriel, Stacey, Kawaguchi, Tomohiro, O'Neill, Keith, Khan, Haumith, Liau, Linda M, Nelson, Stanley F, Rao, P. Nagesh, Mischel, Paul, Pieper, Russell O, Cloughesy, Tim, Leahy, Daniel J, Sellers, William R, Sawyers, Charles L, Meyerson, Matthew, Mellinghoff, Ingo K
Publicado 2006

Subtype-specific genomic alterations define new targets for soft tissue sarcoma therapy

por Barretina, Jordi, Taylor, Barry S., Banerji, Shantanu, Ramos, Alexis H., Lagos-Quintana, Mariana, DeCarolis, Penelope L., Shah, Kinjal, Socci, Nicholas D., Weir, Barbara A., Ho, Alan, Chiang, Derek Y., Reva, Boris, Mermel, Craig, Getz, Gad, Antipin, Yevgenyi, Beroukhim, Rameen, Major, John E., Hatton, Charlie, Nicoletti, Richard, Hanna, Megan, Sharpe, Ted, Fennell, Tim, Cibulskis, Kristian, Onofrio, Robert C., Saito, Tsuyoshi, Shukla, Neerav, Lau, Christopher, Nelander, Sven, Silver, Serena, Sougnez, Carrie, Viale, Agnes, Winckler, Wendy, Maki, Robert G., Garraway, Levi A., Lash, Alex, Greulich, Heidi, Root, David, Sellers, William R., Schwartz, Gary K., Antonescu, Cristina R., Lander, Eric S., Varmus, Harold E., Ladanyi, Marc, Sander, Chris, Meyerson, Matthew, Singer, Samuel
Publicado 2010

MEDULLOBLASTOMA EXOME SEQUENCING UNCOVERS SUBTYPE-SPECIFIC SOMATIC MUTATIONS

por Pugh, Trevor J., Weeraratne, Shyamal Dilhan, Archer, Tenley C., Pomeranz Krummel, Daniel A., Auclair, Daniel, Bochicchio, James, Carneiro, Mauricio O., Carter, Scott L., Cibulskis, Kristian, Erlich, Rachel L., Greulich, Heidi, Lawrence, Michael S., Lennon, Niall J., McKenna, Aaron, Meldrim, James, Ramos, Alex H., Ross, Michael G., Russ, Carsten, Shefler, Erica, Sivachenko, Andrey, Sogoloff, Brian, Stojanov, Petar, Tamayo, Pablo, Mesirov, Jill P., Amani, Vladimir, Teider, Natalia, Sengupta, Soma, Francois, Jessica Pierre, Northcott, Paul A., Taylor, Michael D., Yu, Furong, Crabtree, Gerald R., Kautzman, Amanda G., Gabriel, Stacey B., Getz, Gad, Jäger, Natalie, Jones, David T. W., Lichter, Peter, Pfister, Stefan M., Roberts, Thomas M., Meyerson, Matthew, Pomeroy, Scott L., Cho, Yoon-Jae
Publicado 2012

The landscape of somatic copy-number alteration across human cancers

por Beroukhim, Rameen, Mermel, Craig H., Porter, Dale, Wei, Guo, Raychaudhuri, Soumya, Donovan, Jerry, Barretina, Jordi, Boehm, Jesse S., Dobson, Jennifer, Urashima, Mitsuyoshi, Mc Henry, Kevin T., Pinchback, Reid M., Ligon, Azra H., Cho, Yoon-Jae, Haery, Leila, Greulich, Heidi, Reich, Michael, Winckler, Wendy, Lawrence, Michael S., Weir, Barbara A., Tanaka, Kumiko E., Chiang, Derek Y., Bass, Adam J., Loo, Alice, Hoffman, Carter, Prensner, John, Liefeld, Ted, Gao, Qing, Yecies, Derek, Signoretti, Sabina, Maher, Elizabeth, Kaye, Frederic J., Sasaki, Hidefumi, Tepper, Joel E., Fletcher, Jonathan A., Tabernero, Josep, Baselga, Jose, Tsao, Ming-Sound, DeMichelis, Francesca, Rubin, Mark A., Janne, Pasi A., Daly, Mark J., Nucera, Carmelo, Levine, Ross L., Ebert, Benjamin L., Gabriel, Stacey, Rustgi, Anil K., Antonescu, Cristina R., Ladanyi, Marc, Letai, Anthony, Garraway, Levi A., Loda, Massimo, Beer, David G., True, Lawrence D., Okamoto, Aikou, Pomeroy, Scott L., Singer, Samuel, Golub, Todd R., Lander, Eric S., Getz, Gad, Sellers, William R., Meyerson, Matthew
Publicado 2010