Therapeutic Potential of the Translation Inhibitor Silvestrol in Hepatocellular Cancer

por Kogure, Takayuki, Kinghorn, A. Douglas, Yan, Irene, Bolon, Brad, Lucas, David M., Grever, Michael R., Patel, Tushar
Publicado 2013

Single‐center study of outcomes of patients with hairy cell leukemia who contracted SARS‐CoV‐2

por Annunzio, Kaitlin, Ozga, Michael, Huang, Ying, Anghelina, Mirela, Bhat, Seema A., Blachly, James S., Grever, Michael R., Lozanski, Gerard, Neal, Jasmine, Shindiapina, Polina, Rogers, Kerry A.
Publicado 2023

Up-regulation of CDK9 kinase activity and Mcl-1 stability contributes to the acquired resistance to cyclin-dependent kinase inhibitors in leukemia

por Yeh, Yuh-Ying, Chen, Rong, Hessler, Joshua, Mahoney, Emilia, Lehman, Amy M., Heerema, Nyla A., Grever, Michael R., Plunkett, William, Byrd, John C., Johnson, Amy J.
Publicado 2014

Combined BCL2 and BTK inhibition in CLL demonstrates efficacy after monotherapy with both classes

por Hyak, Jonathan M., Huang, Ying, Rogers, Kerry A., Bhat, Seema A., Grever, Michael R., Byrd, John C., Kittai, Adam S., Jones, Dan, Miller, Cecelia R., Woyach, Jennifer A.
Publicado 2022

Sorbicillinoid Analogues with Cytotoxic and Selective Anti-Aspergillus Activities from Scytalidium album

por El-Elimat, Tamam, Raja, Huzefa A., Figueroa, Mario, Swanson, Steven M., Falkinham, Joseph O., Lucas, David M., Grever, Michael R., Wani, Mansukh C., Pearce, Cedric J., Oberlies, Nicholas H.
Publicado 2014

PRMT5 Is Upregulated in Malignant and Metastatic Melanoma and Regulates Expression of MITF and p27(Kip1)

por Nicholas, Courtney, Yang, Jennifer, Peters, Sara B., Bill, Matthew A., Baiocchi, Robert A., Yan, Fengting, Sïf, Saïd, Tae, Sookil, Gaudio, Eugenio, Wu, Xin, Grever, Michael R., Young, Gregory S., Lesinski, Gregory B.
Publicado 2013

Dinaciclib is a Novel Cyclin Dependent Kinase Inhibitor with Significant Clinical Activity in Relapsed and Refractory Chronic Lymphocytic Leukemia

por Flynn, Joseph, Jones, Jeffrey, Johnson, Amy J., Andritsos, Leslie, Maddocks, Kami, Jaglowski, Samantha, Hessler, Joshua, Grever, Michael R., Ellie, Im, Zhou, Honghong, Zhu, Yali, Zhang, Da, Small, Karen, Bannerji, Rajat, Byrd, John C.
Publicado 2015

Prognostic significance of translocations in the presence of mutated IGHV and of cytogenetic complexity at diagnosis of chronic lymphocytic leukemia

por Heerema, Nyla A., Muthusamy, Natarajan, Zhao, Qiuhong, Ruppert, Amy S., Breidenbach, Heather, Andritsos, Leslie A., Grever, Michael R., Maddocks, Kami J., Woyach, Jennifer, Awan, Farrukh, Long, Meixiao, Gordon, Amber, Coombes, Caitlin, Byrd, John C.
Publicado 2020

Risk Factors for Tumor Lysis Syndrome in patients with Chronic Lymphocytic Leukemia Treated with the Cyclin Dependent Kinase Inhibitor, Flavopiridol

por Blum, Kristie A., Ruppert, Amy S., Woyach, Jennifer A., Jones, Jeffrey A., Andritsos, Leslie, Flynn, Joseph M., Rovin, Brad, Villalona-Calero, Miguel, Ji, Jia, Phelps, Mitchell, Johnson, Amy J., Grever, Michael R., Byrd, John C.
Publicado 2011

Flavopiridol Pharmacogenetics: Clinical and Functional Evidence for the Role of SLCO1B1/OATP1B1 in Flavopiridol Disposition

por Ni, Wenjun, Ji, Jia, Dai, Zunyan, Papp, Audrey, Johnson, Amy J., Ahn, Sunjoo, Farley, Katherine L., Lin, Thomas S., Dalton, James T., Li, Xiaobai, Jarjoura, David, Byrd, John C., Sadee, Wolfgang, Grever, Michael R., Phelps, Mitch A.
Publicado 2010

Curcumin Down-Regulates DNA Methyltransferase 1 and Plays an Anti-Leukemic Role in Acute Myeloid Leukemia

por Yu, Jianhua, Peng, Yong, Wu, Lai-Chu, Xie, Zhiliang, Deng, Youcai, Hughes, Tiffany, He, Shun, Mo, XiaoKui, Chiu, Ming, Wang, Qi-En, He, Xiaoming, Liu, Shujun, Grever, Michael R., Chan, Kenneth K., Liu, Zhongfa
Publicado 2013

Impact of Targeted Therapy on Outcome of Chronic Lymphocytic Leukemia Patients with Relapsed Del(17p13.1) Karyotype at a Single Center

por Stephens, Deborah M., Ruppert, Amy S., Jones, Jeffrey, Woyach, Jennifer, Maddocks, Kami, Jaglowski, Samantha, Andritsos, Leslie A., Flynn, Joseph M., Grever, Michael R., Lozanski, Gerard, Johnson, Amy J., Muthusamy, Natarajan, Heerema, Nyla A., Byrd, John C.
Publicado 2014

Silvestrol exhibits significant in vivo and in vitro antileukemic activities and inhibits FLT3 and miR-155 expressions in acute myeloid leukemia

por Alachkar, Houda, Santhanam, Ramasamy, Harb, Jason G, Lucas, David M, Oaks, Joshua J, Hickey, Christopher J, Pan, Li, Kinghorn, A Douglas, Caligiuri, Michael A, Perrotti, Danilo, Byrd, John C, Garzon, Ramiro, Grever, Michael R, Marcucci, Guido
Publicado 2013

The translation inhibitor silvestrol exhibits direct anti-tumor activity while preserving innate and adaptive immunity against EBV-driven lymphoproliferative disease

por Patton, John T., Lustberg, Mark E., Lozanski, Gerard, Garman, Sabrina L., Towns, William H., Drohan, Callie M., Lehman, Amy, Zhang, Xiaoli, Bolon, Brad, Pan, Li, Kinghorn, A. Douglas, Grever, Michael R., Lucas, David M., Baiocchi, Robert A.
Publicado 2014

Second Cancer Incidence in CLL Patients Receiving BTK Inhibitors

por Bond, David A, Huang, Ying, Fisher, James L, Ruppert, Amy S, Owen, Dwight H, Bertino, Erin M, Rogers, Kerry A, Bhat, Seema A, Grever, Michael R, Jaglowski, Samantha M, Maddocks, Kami J, Byrd, John C, Woyach, Jennifer A
Publicado 2020

Mitochondrial Priming of Chronic Lymphocytic Leukemia Patients Associates Bcl-x(L) Dependence with Alvocidib Response

por Pierceall, William E., Warner, Steven L., Lena, Ryan J., Doykan, Camille, Blake, Noel, Elashoff, Michael, Von Hoff, Daniel, Bearss, David J., Cardone, Michael H., Andritsos, Leslie, Byrd, John C., Lanasa, Mark C., Grever, Michael R., Johnson, Amy J.
Publicado 2014

The long noncoding RNA, treRNA, decreases DNA damage and is associated with poor response to chemotherapy in chronic lymphocytic leukemia

por Miller, Cecelia R., Ruppert, Amy S., Fobare, Sydney, Chen, Timothy L., Liu, Chaomei, Lehman, Amy, Blachly, James S., Zhang, Xiaoli, Lucas, David M., Grever, Michael R., Tallman, Martin S., Flinn, Ian W., Rassenti, Laura Z., Kipps, Thomas J., Sampath, Deepa, Coombes, Kevin R., Hertlein, Erin K.
Publicado 2017

A phase I study of lenalidomide plus chemotherapy with idarubicin and cytarabine in patients with relapsed or refractory acute myeloid leukemia and high‐risk myelodysplastic syndro...

por Saygin, Caner, Larkin, Karilyn, Blachly, James S., Orwick, Shelley, Ngankeu, Apollinaire, Gregory, Charles T., Phelps, Mitch A., Mani, Shylaja, Walker, Alison, Garzon, Ramiro, Vasu, Sumithira, Walsh, Katherine J., Bhatnagar, Bhavana, Klisovic, Rebecca B., Grever, Michael R., Marcucci, Guido, Byrd, John C., Blum, William, Mims, Alice S.
Publicado 2020

Relation of Gene Expression Phenotype to Immunoglobulin Mutation Genotype in B Cell Chronic Lymphocytic Leukemia

por Rosenwald, Andreas, Alizadeh, Ash A., Widhopf, George, Simon, Richard, Davis, R. Eric, Yu, Xin, Yang, Liming, Pickeral, Oxana K., Rassenti, Laura Z., Powell, John, Botstein, David, Byrd, John C., Grever, Michael R., Cheson, Bruce D., Chiorazzi, Nicholas, Wilson, Wyndham H., Kipps, Thomas J., Brown, Patrick O., Staudt, Louis M.
Publicado 2001

A novel regimen for relapsed/refractory adult acute myeloid leukemia using a KMT2A partial tandem duplication targeted therapy: results of phase 1 study NCI 8485

por Mims, Alice S., Mishra, Anjali, Orwick, Shelley, Blachly, James, Klisovic, Rebecca B., Garzon, Ramiro, Walker, Alison R., Devine, Steven M., Walsh, Katherine J., Vasu, Sumithira, Whitman, Susan, Marcucci, Guido, Jones, Daniel, Heerema, Nyla A., Lozanski, Gerard, Caligiuri, Michael A., Bloomfield, Clara D., Byrd, John C., Piekarz, Richard, Grever, Michael R., Blum, William
Publicado 2018