Excretion of the Polymyxin Derivative NAB739 in Murine Urine

por Vaara, Martti, Vaara, Timo, Kuka, Janis, Sevostjanovs, Eduards, Grinberga, Solveiga, Dambrova, Maija, Liepinsh, Edgars
Publicado 2020

Knockout of Tmlhe in mice is not associated with autism spectrum disorder phenotypes or motor dysfunction despite low carnitine levels

por Liepinsh, Edgars, Svalbe, Baiba, Stelfa, Gundega, Grinberga, Solveiga, Zvejniece, Liga, Schiöth, Helgi B., Dambrova, Maija
Publicado 2023

Data on analysis of MK-801 bioavailability in mouse plasma and brain tissue by ultra-performance liquid chromatography-tandem mass spectrometry

por Svalbe, Baiba, Grinberga, Solveiga, Stelfa, Gundega, Vavers, Edijs, Zvejniece, Baiba, Sevostjanovs, Eduards, Dambrova, Maija, Zvejniece, Liga
Publicado 2019

The Cultivation of Chelidonium majus L. Increased the Total Alkaloid Content and Cytotoxic Activity Compared with Those of Wild-Grown Plants

por Krizhanovska, Valerija, Sile, Inga, Kronberga, Arta, Nakurte, Ilva, Mezaka, Ieva, Dambrova, Maija, Pugovics, Osvalds, Grinberga, Solveiga
Publicado 2021

Increased Trimethylamine N-Oxide Is Not Associated with Oxidative Stress Markers in Healthy Aged Women

por Olek, Robert Antoni, Samulak, Joanna Jolanta, Sawicka, Angelika Katarzyna, Hartmane, Dace, Grinberga, Solveiga, Pugovics, Osvalds, Lysiak-Szydlowska, Wieslawa
Publicado 2019

Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice

por Kuka, Janis, Videja, Melita, Makrecka-Kuka, Marina, Liepins, Janis, Grinberga, Solveiga, Sevostjanovs, Eduards, Vilks, Karlis, Liepinsh, Edgars, Dambrova, Maija
Publicado 2020

Mitochondrial-Protective Effects of R-Phenibut after Experimental Traumatic Brain Injury

por Kupats, Einars, Stelfa, Gundega, Zvejniece, Baiba, Grinberga, Solveiga, Vavers, Edijs, Makrecka-Kuka, Marina, Svalbe, Baiba, Zvejniece, Liga, Dambrova, Maija
Publicado 2020

Inhibition of Fatty Acid Metabolism Increases EPA and DHA Levels and Protects against Myocardial Ischaemia-Reperfusion Injury in Zucker Rats

por Kuka, Janis, Makrecka-Kuka, Marina, Vilks, Karlis, Korzh, Stanislava, Cirule, Helena, Sevostjanovs, Eduards, Grinberga, Solveiga, Dambrova, Maija, Liepinsh, Edgars
Publicado 2021

Decreases in Circulating Concentrations of Long-Chain Acylcarnitines and Free Fatty Acids During the Glucose Tolerance Test Represent Tissue-Specific Insulin Sensitivity

por Makarova, Elina, Makrecka-Kuka, Marina, Vilks, Karlis, Volska, Kristine, Sevostjanovs, Eduards, Grinberga, Solveiga, Zarkova-Malkova, Olga, Dambrova, Maija, Liepinsh, Edgars
Publicado 2019

Reduced GFAP Expression in Bergmann Glial Cells in the Cerebellum of Sigma-1 Receptor Knockout Mice Determines the Neurobehavioral Outcomes after Traumatic Brain Injury

por Stelfa, Gundega, Vavers, Edijs, Svalbe, Baiba, Serzants, Rinalds, Miteniece, Anna, Lauberte, Lasma, Grinberga, Solveiga, Gukalova, Baiba, Dambrova, Maija, Zvejniece, Liga
Publicado 2021

Low‐intensity exercise stimulates bioenergetics and increases fat oxidation in mitochondria of blood mononuclear cells from sedentary adults

por Liepinsh, Edgars, Makarova, Elina, Plakane, Liga, Konrade, Ilze, Liepins, Kaspars, Videja, Melita, Sevostjanovs, Eduards, Grinberga, Solveiga, Makrecka‐Kuka, Marina, Dambrova, Maija
Publicado 2020

Wild-Grown and Cultivated Glechoma hederacea L.: Chemical Composition and Potential for Cultivation in Organic Farming Conditions

por Sile, Inga, Krizhanovska, Valerija, Nakurte, Ilva, Mezaka, Ieva, Kalane, Laura, Filipovs, Jevgenijs, Vecvanags, Alekss, Pugovics, Osvalds, Grinberga, Solveiga, Dambrova, Maija, Kronberga, Arta
Publicado 2022

3-(Adenosylthio)benzoic Acid Derivatives as SARS-CoV-2 Nsp14 Methyltransferase Inhibitors

por Bobileva, Olga, Bobrovs, Raitis, Sirma, Evelina Elva, Kanepe, Iveta, Bula, Anna L., Patetko, Liene, Ramata-Stunda, Anna, Grinberga, Solveiga, Jirgensons, Aigars, Jaudzems, Kristaps
Publicado 2023

Efficacy of Proanthocyanidins from Pelargonium sidoides Root Extract in Reducing P. gingivalis Viability While Preserving Oral Commensal S. salivarius

por Savickiene, Nijole, Jekabsone, Aiste, Raudone, Lina, Abdelgeliel, Asmaa S., Cochis, Andrea, Rimondini, Lia, Makarova, Elina, Grinberga, Solveiga, Pugovics, Osvalds, Dambrova, Maija, Pacauskiene, Ingrida M., Basevičiene, Nomeda, Viškelis, Pranas
Publicado 2018

The Association of Circulating L-Carnitine, γ-Butyrobetaine and Trimethylamine N-Oxide Levels with Gastric Cancer

por Stonāns, Ilmārs, Kuzmina, Jelizaveta, Poļaka, Inese, Grīnberga, Solveiga, Sevostjanovs, Eduards, Liepiņš, Edgars, Aleksandraviča, Ilona, Šantare, Daiga, Kiršners, Arnis, Škapars, Roberts, Pčolkins, Andrejs, Tolmanis, Ivars, Sīviņš, Armands, Leja, Mārcis, Dambrova, Maija
Publicado 2023

Potent SARS-CoV-2 mRNA Cap Methyltransferase Inhibitors by Bioisosteric Replacement of Methionine in SAM Cosubstrate

por Bobiļeva, Olga, Bobrovs, Raitis, Kaņepe, Iveta, Patetko, Liene, Kalniņš, Gints, Šišovs, Mihails, Bula, Anna L., Gri̅nberga, Solveiga, Borodušķis, Ma̅rtiņš, Ramata-Stunda, Anna, Rostoks, Nils, Jirgensons, Aigars, Ta̅rs, Kaspars, Jaudzems, Kristaps
Publicado 2021

Discovery of SARS-CoV-2 Nsp14 and Nsp16 Methyltransferase Inhibitors by High-Throughput Virtual Screening

por Bobrovs, Raitis, Kanepe, Iveta, Narvaiss, Nauris, Patetko, Liene, Kalnins, Gints, Sisovs, Mihails, Bula, Anna L., Grinberga, Solveiga, Boroduskis, Martins, Ramata-Stunda, Anna, Rostoks, Nils, Jirgensons, Aigars, Tars, Kaspars, Jaudzems, Kristaps
Publicado 2021

Model‐Informed Drug Development for Antimicrobials: Translational PK and PK/PD Modeling to Predict an Efficacious Human Dose for Apramycin

por Sou, Tomás, Hansen, Jon, Liepinsh, Edgars, Backlund, Maria, Ercan, Onur, Grinberga, Solveiga, Cao, Sha, Giachou, Paraskevi, Petersson, Anna, Tomczak, Magdalena, Urbas, Malgorzata, Zabicka, Dorota, Vingsbo Lundberg, Carina, Hughes, Diarmaid, Hobbie, Sven N., Friberg, Lena E.
Publicado 2020

Macrocyclic Peptidomimetic Plasmepsin X Inhibitors with Potent In Vitro and In Vivo Antimalarial Activity

por Kovada, Vadims, Withers-Martinez, Chrislaine, Bobrovs, Raitis, Ce̅rule, Hele̅na, Liepins, Edgars, Grinberga, Solveiga, Hackett, Fiona, Collins, Christine R., Kreicberga, Agrita, Jiménez-Díaz, María Belén, Angulo-Barturen, Iñigo, Rasina, Dace, Suna, Edgars, Jaudzems, Kristaps, Blackman, Michael J., Jirgensons, Aigars
Publicado 2023

Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis

por Becker, Katja, Cao, Sha, Nilsson, Anna, Erlandsson, Maria, Hotop, Sven-Kevin, Kuka, Janis, Hansen, Jon, Haldimann, Klara, Grinberga, Solveiga, Berruga-Fernández, Talia, Huseby, Douglas L., Shariatgorji, Reza, Lindmark, Evelina, Platzack, Björn, Böttger, Erik C., Crich, David, Friberg, Lena E., Vingsbo Lundberg, Carina, Hughes, Diarmaid, Brönstrup, Mark, Andrén, Per E., Liepinsh, Edgars, Hobbie, Sven N.
Publicado 2021