MTBP and MYC: A Dynamic Duo in Proliferation, Cancer, and Aging

por Grieb, Brian C., Eischen, Christine M.
Publicado 2022

Haploinsufficiency of the Myc regulator Mtbp extends survival and delays tumor development in aging mice

por Grieb, Brian C., Boyd, Kelli, Mitra, Ramkrishna, Eischen, Christine M.
Publicado 2016

A deficiency in Mdm2 binding protein (MTBP) inhibits Myc-induced B cell proliferation and lymphomagenesis

por Odvody, Jessica, Vincent, Tiffaney, Arrate, Maria Pia, Grieb, Brian, Wang, Shuo, Garriga, Judit, Lozano, Guillermina, Iwakuma, Tomoo, Haines, Dale S., Eischen, Christine M.
Publicado 2010

Interaction of MYC with Host Cell Factor-1 is meditated by the evolutionarily-conserved Myc box IV motif

por Thomas, Lance R., Foshage, Audra M., Weissmiller, April M., Popay, Tessa M., Grieb, Brian C., Qualls, Susan J., Ng, Victoria, Carboneau, Bethany, Lorey, Shelly, Eischen, Christine M., Tansey, William P.
Publicado 2015

Synergistic action of WDR5 and HDM2 inhibitors in SMARCB1-deficient cancer cells

por Florian, Andrea C, Woodley, Chase M, Wang, Jing, Grieb, Brian C, Slota, Macey J, Guerrazzi, Kiana, Hsu, Chih-Yuan, Matlock, Brittany K, Flaherty, David K, Lorey, Shelly L, Fesik, Stephen W, Howard, Gregory C, Liu, Qi, Weissmiller, April M, Tansey, William P
Publicado 2022

Ribosome subunit attrition and activation of the p53–MDM4 axis dominate the response of MLL-rearranged cancer cells to WDR5 WIN site inhibition

por Howard, Gregory C., Wang, Jing, Rose, Kristie Lindsey, Patel, Purvi, Tsui, Tina, Florian, Andrea C., Lorey, Shelly L., Grieb, Brian C., Smith, Brianna N., Slota, Macey J., Reynolds, Elizabeth M., Goswami, Soumita, Savona, Michael R., Lee, Taekyu, Fesik, Stephen W., Liu, Qi, Tansey, William P.
Publicado 2023

Structure-based discovery of potent WD repeat domain 5 inhibitors that demonstrate efficacy and safety in preclinical animal models

por Teuscher, Kevin B., Chowdhury, Somenath, Meyers, Kenneth M., Tian, Jianhua, Sai, Jiqing, Van Meveren, Mayme, South, Taylor M., Sensintaffar, John L., Rietz, Tyson A., Goswami, Soumita, Wang, Jing, Grieb, Brian C., Lorey, Shelly L., Howard, Gregory C., Liu, Qi, Moore, William J., Stott, Gordon M., Tansey, William P., Lee, Taekyu, Fesik, Stephen W.
Publicado 2022