Chimeric Antigen Receptor T Cell Therapy in Acute Myeloid Leukemia: Trials and Tribulations

por Garg, Swati, Ni, Wei, Griffin, James D., Sattler, Martin
Publicado 2023

Spotlight on midostaurin in the treatment of FLT3-mutated acute myeloid leukemia and systemic mastocytosis: design, development, and potential place in therapy

por Weisberg, Ellen, Sattler, Martin, Manley, Paul W, Griffin, James D
Publicado 2017

Gene expression profiling analysis of CRTC1-MAML2 fusion oncogene-induced transcriptional program in human mucoepidermoid carcinoma cells

por Chen, Jie, Li, Jian-Liang, Chen, Zirong, Griffin, James D., Wu, Lizi
Publicado 2015

Post‐transplant maintenance therapy in patients with FLT3‐mutated acute myeloid leukemia: Real‐world treatment patterns and outcomes

por Griffin, James D., Song, Yan, Yang, Hongbo, Freimark, Jonathan, Shah, Manasee V.
Publicado 2021

Repurposing clinically available drugs and therapies for pathogenic targets to combat SARS‐CoV‐2

por Xue, Yiying, Mei, Husheng, Chen, Yisa, Griffin, James D., Liu, Qingsong, Weisberg, Ellen, Yang, Jing
Publicado 2023

NADPH oxidases regulate cell growth and migration in myeloid cells transformed by oncogenic tyrosine kinases

por Reddy, Mamatha M., Fernandes, Margret S., Salgia, Ravi, Levine, Ross L., Griffin, James D., Sattler, Martin
Publicado 2010

Treatment patterns and healthcare resource utilization in patients with FLT3‐mutated and wild‐type acute myeloid leukemia: A medical chart study

por Griffin, James D., Yang, Hongbo, Song, Yan, Kinrich, David, Shah, Manasee V., Bui, Cat N.
Publicado 2019

Kinase domain mutations confer resistance to novel inhibitors targeting JAK2V617F in myeloproliferative neoplasms

por Deshpande, Anagha, Reddy, Mamatha M., Schade, Georg O.M., Ray, Arghya, Chowdary, Tirumala K., Griffin, James D., Sattler, Martin
Publicado 2011

Patient and Physician Preferences for Acute Myeloid Leukemia Maintenance Treatments Following Hematopoietic Stem Cell Transplantation

por Saini, Lalit, Griffin, James D, Pandya, Bhavik J, Shah, Manasee V, Zhou, Mo, Yang, Hongbo, Song, Yan, Marshall, Deborah A
Publicado 2023

Inhibition of SDF-1-induced migration of oncogene-driven myeloid leukemia by the L-RNA aptamer (Spiegelmer), NOX-A12, and potentiation of tyrosine kinase inhibition

por Weisberg, Ellen L., Sattler, Martin, Azab, Abdel Kareem, Eulberg, Dirk, Kruschinski, Anna, Manley, Paul W., Stone, Richard, Griffin, James D.
Publicado 2017

Reversible Resistance Induced by FLT3 Inhibition: A Novel Resistance Mechanism in Mutant FLT3-Expressing Cells

por Weisberg, Ellen, Ray, Arghya, Nelson, Erik, Adamia, Sophia, Barrett, Rosemary, Sattler, Martin, Zhang, Chengsheng, Daley, John F., Frank, David, Fox, Edward, Griffin, James D.
Publicado 2011

Acute myeloid leukemia cells require 6-phosphogluconate dehydrogenase for cell growth and NADPH-dependent metabolic reprogramming

por Bhanot, Haymanti, Weisberg, Ellen L., Reddy, Mamatha M., Nonami, Atsushi, Neuberg, Donna, Stone, Richard M., Podar, Klaus, Salgia, Ravi, Griffin, James D., Sattler, Martin
Publicado 2017

Repurposing of Kinase Inhibitors for Treatment of COVID-19

por Weisberg, Ellen, Parent, Alexander, Yang, Priscilla L., Sattler, Martin, Liu, Qingsong, Liu, Qingwang, Wang, Jinhua, Meng, Chengcheng, Buhrlage, Sara J., Gray, Nathanael, Griffin, James D.
Publicado 2020

The JAK2V617F oncogene requires expression of inducible phosphofructokinase/fructose-bisphosphatase 3 for cell growth and increased metabolic activity

por Reddy, Mamatha M., Fernandes, Margret S., Deshpande, Anagha, Weisberg, Ellen, Inguilizian, Haig V., Abdel-Wahab, Omar, Kung, Andrew L., Levine, Ross L., Griffin, James D., Sattler, Martin
Publicado 2011

Inhibition of the deubiquitinase USP10 induces degradation of SYK

por Yang, Jing, Meng, Chengcheng, Weisberg, Ellen, Case, Abigail, Lamberto, Ilaria, Magin, Robert S., Adamia, Sophia, Wang, Jinhua, Gray, Nathanael, Liu, Suiyang, Stone, Richard, Sattler, Martin, Buhrlage, Sara, Griffin, James D.
Publicado 2020

Selective Akt Inhibitors Synergize with Tyrosine Kinase Inhibitors and Effectively Override Stroma-Associated Cytoprotection of Mutant FLT3-Positive AML Cells

por Weisberg, Ellen, Liu, Qingsong, Zhang, Xin, Nelson, Erik, Sattler, Martin, Liu, Feiyang, Nicolais, Maria, Zhang, Jianming, Mitsiades, Constantine, Smith, Robert W., Stone, Richard, Galinsky, Ilene, Nonami, Atsushi, Griffin, James D., Gray, Nathanael
Publicado 2013

Structure of a pseudokinase domain switch that controls oncogenic activation of Jak kinases

por Toms, Angela V., Deshpande, Anagha, McNally, Randall, Jeong, Youngjee, Rogers, Julia M., Kim, Chae Un, Gruner, Sol M., Ficarro, Scott B., Marto, Jarrod A., Sattler, Martin, Griffin, James D., Eck, Michael J.
Publicado 2013

Effects of the multi‐kinase inhibitor midostaurin in combination with chemotherapy in models of acute myeloid leukaemia

por Weisberg, Ellen, Meng, Chengcheng, Case, Abigail E., Tiv, Hong L., Gokhale, Prafulla C., Buhrlage, Sara J., Yang, Jing, Liu, Xiaoxi, Wang, Jinhua, Gray, Nathanael, Adamia, Sophia, Sattler, Martin, Stone, Richard, Griffin, James D.
Publicado 2020

The combination of FLT3 and SYK kinase inhibitors is toxic to leukaemia cells with CBL mutations

por Weisberg, Ellen, Meng, Chengcheng, Case, Abigail E., Tiv, Hong L., Gokhale, Prafulla C., Toure, Anthia A., Buhrlage, Sara, Liu, Xiaoxi, Wang, Jinhua, Gray, Nathanael, Stone, Richard, Adamia, Sophia, Winer, Eric, Sattler, Martin, Griffin, James D.
Publicado 2020

The CRTC1-MAML2 fusion is the major oncogenic driver in mucoepidermoid carcinoma

por Chen, Zirong, Ni, Wei, Li, Jian-Liang, Lin, Shuibin, Zhou, Xin, Sun, Yuping, Li, Jennifer W., Leon, Marino E., Hurtado, Maria D., Zolotukhin, Sergei, Liu, Chen, Lu, Jianrong, Griffin, James D., Kaye, Frederic J., Wu, Lizi
Publicado 2021