Pharmacologic inhibition of RGD‐binding integrins ameliorates fibrosis and improves function following kidney injury

por Basta, Jeannine, Robbins, Lynn, Stout, Lisa, Prinsen, Michael J., Griggs, David W., Rauchman, Michael
Publicado 2020

An Inhibitor of Arginine‐Glycine‐Aspartate‐Binding Integrins Reverses Fibrosis in a Mouse Model of Nonalcoholic Steatohepatitis

por Ulmasov, Barbara, Noritake, Hidenao, Carmichael, Peter, Oshima, Kiyoko, Griggs, David W., Neuschwander‐Tetri, Brent A.
Publicado 2018

Clinical and microbiologic efficacy of the piperazine-based drug lead MMV665917 in the dairy calf cryptosporidiosis model

por Stebbins, Erin, Jumani, Rajiv S., Klopfer, Connor, Barlow, John, Miller, Peter, Campbell, Mary A., Meyers, Marvin J., Griggs, David W., Huston, Christopher D.
Publicado 2018

Inhibitors of Arg-Gly-Asp-Binding Integrins Reduce Development of Pancreatic Fibrosis in Mice

por Ulmasov, Barbara, Neuschwander-Tetri, Brent A., Lai, Jinping, Monastyrskiy, Vladimir, Bhat, Trisha, Yates, Matthew P., Oliva, Jonathan, Prinsen, Michael J., Ruminski, Peter G., Griggs, David W.
Publicado 2016

Pharmacologic Comparison of Clinical Neutral Endopeptidase Inhibitors in a Rat Model of Acute Secretory Diarrhea

por Griggs, David W., Prinsen, Michael J., Oliva, Jonathan, Campbell, Mary A., Arnett, Stacy D., Tajfirouz, Deena, Ruminski, Peter G., Yu, Ying, Bond, Brian R., Ji, Yuhua, Neckermann, Georg, Choy, Robert K. M., de Hostos, Eugenio, Meyers, Marvin J.
Publicado 2016

A Macrophage-Pericyte Axis Directs Tissue Restoration via Amphiregulin-Induced Transforming Growth Factor Beta Activation

por Minutti, Carlos M., Modak, Rucha V., Macdonald, Felicity, Li, Fengqi, Smyth, Danielle J., Dorward, David A., Blair, Natalie, Husovsky, Connor, Muir, Andrew, Giampazolias, Evangelos, Dobie, Ross, Maizels, Rick M., Kendall, Timothy J., Griggs, David W., Kopf, Manfred, Henderson, Neil C., Zaiss, Dietmar M.
Publicado 2019

Selective αv integrin depletion identifies a core, targetable molecular pathway that regulates fibrosis across solid organs

por Henderson, Neil C, Arnold, Thomas D, Katamura, Yoshio, Giacomini, Marilyn M, Rodriguez, Juan D, McCarty, Joseph H, Pellicoro, Antonella, Raschperger, Elisabeth, Betsholtz, Christer, Ruminski, Peter G, Griggs, David W, Prinsen, Michael J, Maher, Jacquelyn J, Iredale, John P, Lacy-Hulbert, Adam, Adams, Ralf H, Sheppard, Dean
Publicado 2013