HGG-31. HISTONE H3.3 G34R/V MUTATIONS STIMULATE PEDIATRIC HIGH-GRADE GLIOMA FORMATION THROUGH THE INDUCTION OF CHROMOSOMAL INSTABILITY

por Grigore, Florina, Robinson, James, Langfald, Alyssa, Hinchcliffe, Edward, Day, Charles
Publicado 2021

Pioneering models of pediatric brain tumors

por Grigore, Florina-Nicoleta, Yang, Serena Johanna, Chen, Clark C., Koga, Tomoyuki
Publicado 2023

HGG-30. H3.3 G34R/V mutations disrupt H3.3 mitotic phosphorylation leading to high-grade glioma formation through the induction of chromosomal instability

por Day, Charles, Grigore, Florina, Hakkim, Faruck, Langfald, Alyssa, Hinchcliffe, Edward, Robinson, James
Publicado 2022

BRAF inhibition in melanoma is associated with the dysregulation of histone methylation and histone methyltransferases

por Grigore, Florina, Yang, Hana, Hanson, Nicholas D., VanBrocklin, Matthew W., Sarver, Aaron L., Robinson, James P.
Publicado 2020

DIPG-05. HISTONE H3.3 K27M IMPAIRS SER31 PHOSPHORYLATION, RESULTING IN CHROMOSOMAL INSTABILITY, LOSS OF CELL CYCLE CHECKPOINT CONTROL, AND TUMOR FORMATION

por Day, Charles, Langfald, Alyssa, Grigore, Florina, Fadness, Sela, Sepaniac, Leslie, Stumpff, Jason, Vaughan, Kevin, Robinson, James, Hinchcliffe, Edward
Publicado 2020

Cooperativity between H3.3K27M and PDGFRA poses multiple therapeutic vulnerabilities in human iPSC-derived diffuse midline glioma avatars

por Skinner, Kasey R., Koga, Tomoyuki, Miki, Shunichiro, Gruener, Robert F., Grigore, Florina-Nicoleta, Torii, Emma H., Seelig, Davis M., Suzuki, Yuta, Kawauchi, Daisuke, Lin, Benjamin, Malicki, Denise M., Chen, Clark C., Benveniste, Etty N., Patel, Rakesh P., McFarland, Braden C., Huang, R. Stephanie, Jones, Chris, Mackay, Alan, Miller, C. Ryan, Furnari, Frank B.
Publicado 2023