Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops

por Williamson, Iain, Boyle, Shelagh, Grimes, Graeme R, Friman, Elias T, Bickmore, Wendy A
Publicado 2023

Correction: Dispersal of PRC1 condensates disrupts polycomb chromatin domains and loops

por Williamson, Iain, Boyle, Shelagh, Grimes, Graeme R, Friman, Elias T, Bickmore, Wendy A
Publicado 2023

PRC1 and PRC2 Are Not Required for Targeting of H2A.Z to Developmental Genes in Embryonic Stem Cells

por Illingworth, Robert S., Botting, Catherine H., Grimes, Graeme R., Bickmore, Wendy A., Eskeland, Ragnhild
Publicado 2012

Psip1/Ledgf p52 Binds Methylated Histone H3K36 and Splicing Factors and Contributes to the Regulation of Alternative Splicing

por Pradeepa, Madapura M., Sutherland, Heidi G., Ule, Jernej, Grimes, Graeme R., Bickmore, Wendy A.
Publicado 2012

Psip1/Ledgf p75 restrains Hox gene expression by recruiting both trithorax and polycomb group proteins

por Pradeepa, Madapura M., Grimes, Graeme R., Taylor, Gillian C.A., Sutherland, Heidi G., Bickmore, Wendy A.
Publicado 2014

Histone H3 globular domain acetylation identifies a new class of enhancers

por Pradeepa, Madapura M, Grimes, Graeme R, Kumar, Yatendra, Olley, Gabrielle, Taylor, Gillian C A, Schneider, Robert, Bickmore, Wendy A
Publicado 2016

Decreased Enhancer-Promoter Proximity Accompanying Enhancer Activation

por Benabdallah, Nezha S., Williamson, Iain, Illingworth, Robert S., Kane, Lauren, Boyle, Shelagh, Sengupta, Dipta, Grimes, Graeme R., Therizols, Pierre, Bickmore, Wendy A.
Publicado 2019

Human centromere repositioning activates transcription and opens chromatin fibre structure

por Naughton, Catherine, Huidobro, Covadonga, Catacchio, Claudia R., Buckle, Adam, Grimes, Graeme R., Nozawa, Ryu-Suke, Purgato, Stefania, Rocchi, Mariano, Gilbert, Nick
Publicado 2022

FAK regulates IL-33 expression by controlling chromatin accessibility at c-Jun motifs

por Griffith, Billie G. C., Upstill-Goddard, Rosanna, Brunton, Holly, Grimes, Graeme R., Biankin, Andrew V., Serrels, Bryan, Byron, Adam, Frame, Margaret C.
Publicado 2021

Cornelia de Lange syndrome-associated mutations cause a DNA damage signalling and repair defect

por Olley, Gabrielle, Pradeepa, Madapura M., Grimes, Graeme R., Piquet, Sandra, Polo, Sophie E., FitzPatrick, David R., Bickmore, Wendy A., Boumendil, Charlene
Publicado 2021

Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip

por Pradeepa, Madapura M., McKenna, Fionnuala, Taylor, Gillian C. A., Bengani, Hemant, Grimes, Graeme R., Wood, Andrew J., Bhatia, Shipra, Bickmore, Wendy A.
Publicado 2017

GPX-Macrophage Expression Atlas: A database for expression profiles of macrophages challenged with a variety of pro-inflammatory, anti-inflammatory, benign and pathogen insults

por Grimes, Graeme R, Moodie, Stuart, Beattie, John S, Craigon, Marie, Dickinson, Paul, Forster, Thorsten, Livingston, Andrew D, Mewissen, Muriel, Robertson, Kevin A, Ross, Alan J, Sing, Garwin, Ghazal, Peter
Publicado 2005

Human β-defensin 3 affects the activity of pro-inflammatory pathways associated with MyD88 and TRIF

por Semple, Fiona, MacPherson, Heather, Webb, Sheila, Cox, Sarah L, Mallin, Lucy J, Tyrrell, Christine, Grimes, Graeme R, Semple, Colin A, Nix, Matthew A, Millhauser, Glenn L, Dorin, Julia R
Publicado 2011

DNA Methylation Directs Polycomb-Dependent 3D Genome Re-organization in Naive Pluripotency

por McLaughlin, Katy, Flyamer, Ilya M., Thomson, John P., Mjoseng, Heidi K., Shukla, Ruchi, Williamson, Iain, Grimes, Graeme R., Illingworth, Robert S., Adams, Ian R., Pennings, Sari, Meehan, Richard R., Bickmore, Wendy A.
Publicado 2019

Characterisation of a nucleo-adhesome

por Byron, Adam, Griffith, Billie G. C., Herrero, Ana, Loftus, Alexander E. P., Koeleman, Emma S., Kogerman, Linda, Dawson, John C., McGivern, Niamh, Culley, Jayne, Grimes, Graeme R., Serrels, Bryan, von Kriegsheim, Alex, Brunton, Valerie G., Frame, Margaret C.
Publicado 2022

In Vivo Modeling of Patient Genetic Heterogeneity Identifies New Ways to Target Cholangiocarcinoma

por Younger, Nicholas T., Wilson, Mollie L., Martinez Lyons, Anabel, Jarman, Edward J., Meynert, Alison M., Grimes, Graeme R., Gournopanos, Konstantinos, Waddell, Scott H., Tennant, Peter A., Wilson, David H., Guest, Rachel V., Wigmore, Stephen J., Acosta, Juan Carlos, Kendall, Timothy J., Taylor, Martin S., Sproul, Duncan, Mill, Pleasantine, Boulter, Luke
Publicado 2022

Monoallelic variants resulting in substitutions of MAB21L1 Arg51 Cause Aniridia and microphthalmia

por Hall, Hildegard Nikki, Bengani, Hemant, Hufnagel, Robert B., Damante, Giuseppe, Ansari, Morad, Marsh, Joseph A., Grimes, Graeme R., von Kriegsheim, Alex, Moore, David, McKie, Lisa, Rahmat, Jamalia, Mio, Catia, Blyth, Moira, Keng, Wee Teik, Islam, Lily, McEntargart, Meriel, Mannens, Marcel M., Heyningen, Veronica Van, Rainger, Joe, Brooks, Brian P., FitzPatrick, David R.
Publicado 2022