Improved detection of measurable residual disease in acute myeloid leukemia

por Zhang, Xuan, Grimes, H. Leighton
Publicado 2023

Why Single-Cell Sequencing Has Promise in MDS

por Zhang, Xuan, Grimes, H. Leighton
Publicado 2021

pyInfinityFlow: optimized imputation and analysis of high-dimensional flow cytometry data for millions of cells

por Ferchen, Kyle, Salomonis, Nathan, Grimes, H Leighton
Publicado 2023

The Human Cell Atlas bone marrow single-cell interactive web portal

por Hay, Stuart B., Ferchen, Kyle, Chetal, Kashish, Grimes, H. Leighton, Salomonis, Nathan
Publicado 2018

The 3′ Region of the Chicken Hypersensitive Site-4 Insulator Has Properties Similar to Its Core and Is Required for Full Insulator Activity

por Arumugam, Paritha I., Urbinati, Fabrizia, Velu, Chinavenmeni S., Higashimoto, Tomoyasu, Grimes, H. Leighton, Malik, Punam
Publicado 2009

Time resolved quantitative phospho-tyrosine analysis reveals Bruton’s Tyrosine kinase mediated signaling downstream of the mutated granulocyte-colony stimulating factor receptors

por Dwivedi, Pankaj, Muench, David E., Wagner, Michael, Azam, Mohammad, Grimes, H. Leighton, Greis, Kenneth D.
Publicado 2018

Phospho serine and threonine analysis of normal and mutated granulocyte colony stimulating factor receptors

por Dwivedi, Pankaj, Muench, David E., Wagner, Michael, Azam, Mohammad, Grimes, H. Leighton, Greis, Kenneth D.
Publicado 2019

Single-cell analysis of mixed-lineage states leading to a binary cell fate choice

por Olsson, Andre, Venkatasubramanian, Meenakshi, Chaudhri, Viren K., Aronow, Bruce J., Salomonis, Nathan, Singh, Harinder, Grimes, H. Leighton
Publicado 2016

S6K1 determines the metabolic requirements for BCR-ABL survival

por Barger, Jennifer F., Gallo, Catherine A., Tandon, Preeti, Liu, Hongqi, Sullivan, Ashley, Grimes, H. Leighton, Plas, David R.
Publicado 2012

GM-CSF Programs Hematopoietic Stem and Progenitor Cells During Candida albicans Vaccination for Protection Against Reinfection

por Bono, Cristina, Guerrero, Paula, Jordán-Pla, Antonio, Erades, Ana, Salomonis, Nathan, Grimes, H. Leighton, Gil, M. Luisa, Yáñez, Alberto
Publicado 2021

Bim/Bcl-2 balance is critical for maintaining naive and memory T cell homeostasis

por Wojciechowski, Sara, Tripathi, Pulak, Bourdeau, Tristan, Acero, Luis, Grimes, H. Leighton, Katz, Jonathan D., Finkelman, Fred D., Hildeman, David A.
Publicado 2007

Enhanced MAPK signaling is essential for CSF3R induced leukemia

por Rohrabaugh, Sara, Kesarwani, Meenu, Kincaid, Zachary, Huber, Erika, Leddonne, Jennifer, Siddiqui, Zain, Khalifa, Yara, Komurov, Kakajan, Grimes, H. Leighton, Azam, Mohammad
Publicado 2016

The miR-23a~27a~24-2 microRNA cluster buffers transcription and signaling pathways during hematopoiesis

por Kurkewich, Jeffrey L., Hansen, Justin, Klopfenstein, Nathan, Zhang, Helen, Wood, Christian, Boucher, Austin, Hickman, Joseph, Muench, David E., Grimes, H. Leighton, Dahl, Richard
Publicado 2017

Distinct Roles of Cdc42 in Thymopoiesis and Effector and Memory T Cell Differentiation

por Guo, Fukun, Zhang, Shuangmin, Tripathi, Pulak, Mattner, Jochen, Phelan, James, Sproles, Alyssa, Mo, Jun, Wills-Karp, Marsha, Grimes, H. Leighton, Hildeman, David, Zheng, Yi
Publicado 2011

Clonal hematopoiesis of indeterminate potential and its impact on patient trajectories after stem cell transplantation

por Park, Derek S., Akuffo, Afua A., Muench, David E., Grimes, H. Leighton, Epling-Burnette, Pearlie K., Maini, Philip K., Anderson, Alexander R. A., Bonsall, Michael B.
Publicado 2019

DoubletDecon: Deconvoluting Doublets from Single-Cell RNA-Sequencing Data

por DePasquale, Erica A.K., Schnell, Daniel J., Van Camp, Pieter-Jan, Valiente-Alandí, Íñigo, Blaxall, Burns C., Grimes, H. Leighton, Singh, Harinder, Salomonis, Nathan
Publicado 2019

The Molecular Signature of Megakaryocyte-Erythroid Progenitors Reveals a Role for the Cell Cycle in Fate Specification

por Lu, Yi-Chien, Sanada, Chad, Xavier-Ferrucio, Juliana, Wang, Lin, Zhang, Ping-Xia, Grimes, H. Leighton, Venkatasubramanian, Meenakshi, Chetal, Kashish, Aronow, Bruce, Salomonis, Nathan, Krause, Diane S.
Publicado 2018

cellHarmony: cell-level matching and holistic comparison of single-cell transcriptomes

por DePasquale, Erica A K, Schnell, Daniel, Dexheimer, Phillip, Ferchen, Kyle, Hay, Stuart, Chetal, Kashish, Valiente-Alandí, Íñigo, Blaxall, Burns C, Grimes, H Leighton, Salomonis, Nathan
Publicado 2019

Growth factor independent-1 Maintains Notch1-Dependent Transcriptional Programming of Lymphoid Precursors

por Phelan, James D., Saba, Ingrid, Zeng, Hui, Kosan, Christian, Messer, Malynda S., Olsson, H. Andre, Fraszczak, Jennifer, Hildeman, David A., Aronow, Bruce J., Möröy, Tarik, Grimes, H. Leighton
Publicado 2013

Obesity alters the long-term fitness of the hematopoietic stem cell compartment through modulation of Gfi1 expression

por Lee, Jung-Mi, Govindarajah, Vinothini, Goddard, Bryan, Hinge, Ashwini, Muench, David E., Filippi, Marie-Dominique, Aronow, Bruce, Cancelas, Jose A., Salomonis, Nathan, Grimes, H. Leighton, Reynaud, Damien
Publicado 2018