Time-dependent inhibition of PHD2

por Tcholakov, Isabelle, Grimshaw, Charles E., Shi, Lihong, Kiryanov, Andre, Murphy, Sean T., Larson, Christopher J., Plonowski, Artur, Ermolieff, Jacques
Publicado 2017

Trelagliptin (SYR-472, Zafatek), Novel Once-Weekly Treatment for Type 2 Diabetes, Inhibits Dipeptidyl Peptidase-4 (DPP-4) via a Non-Covalent Mechanism

por Grimshaw, Charles E., Jennings, Andy, Kamran, Ruhi, Ueno, Hikaru, Nishigaki, Nobuhiro, Kosaka, Takuo, Tani, Akiyoshi, Sano, Hiroki, Kinugawa, Yoshinobu, Koumura, Emiko, Shi, Lihong, Takeuchi, Koji
Publicado 2016

TP-064, a potent and selective small molecule inhibitor of PRMT4 for multiple myeloma

por Nakayama, Kazuhide, Szewczyk, Magdalena M., dela Sena, Carlo, Wu, Hong, Dong, Aiping, Zeng, Hong, Li, Fengling, de Freitas, Renato Ferreira, Eram, Mohammad S., Schapira, Matthieu, Baba, Yuji, Kunitomo, Mihoko, Cary, Douglas R., Tawada, Michiko, Ohashi, Akihiro, Imaeda, Yasuhiro, Saikatendu, Kumar Singh, Grimshaw, Charles E., Vedadi, Masoud, Arrowsmith, Cheryl H., Barsyte-Lovejoy, Dalia, Kiba, Atsushi, Tomita, Daisuke, Brown, Peter J.
Publicado 2018

Donated chemical probes for open science

por Müller, Susanne, Ackloo, Suzanne, Arrowsmith, Cheryl H, Bauser, Marcus, Baryza, Jeremy L, Blagg, Julian, Böttcher, Jark, Bountra, Chas, Brown, Peter J, Bunnage, Mark E, Carter, Adrian J, Damerell, David, Dötsch, Volker, Drewry, David H, Edwards, Aled M, Edwards, James, Elkins, Jon M, Fischer, Christian, Frye, Stephen V, Gollner, Andreas, Grimshaw, Charles E, IJzerman, Adriaan, Hanke, Thomas, Hartung, Ingo V, Hitchcock, Steve, Howe, Trevor, Hughes, Terry V, Laufer, Stefan, Li, Volkhart MJ, Liras, Spiros, Marsden, Brian D, Matsui, Hisanori, Mathias, John, O'Hagan, Ronan C, Owen, Dafydd R, Pande, Vineet, Rauh, Daniel, Rosenberg, Saul H, Roth, Bryan L, Schneider, Natalie S, Scholten, Cora, Singh Saikatendu, Kumar, Simeonov, Anton, Takizawa, Masayuki, Tse, Chris, Thompson, Paul R, Treiber, Daniel K, Viana, Amélia YI, Wells, Carrow I, Willson, Timothy M, Zuercher, William J, Knapp, Stefan, Mueller-Fahrnow, Anke
Publicado 2018