Safety, tolerability, pharmacokinetics, and pharmacodynamics of a TLR7 agonist prodrug RO6870868 in healthy volunteers

por Grippo, Joseph F., Folitar, Ilia, Passe, Sharon, Jiang, Qiudi, Rodriguez, Ignacio, Fettner, Scott H., Calleja, Elizabeth
Publicado 2021

A Single and Multiple Ascending Dose Study of Toll‐Like Receptor 7 Agonist (RO7020531) in Chinese Healthy Volunteers

por Luk, Andrea, Jiang, Qiudi, Glavini, Katerina, Triyatni, Miriam, Zhao, Na, Racek, Tomas, Zhu, Yonghong, Grippo, Joseph F.
Publicado 2020

A single ascending dose study of single‐stranded oligodeoxyribonucleotide RO7062931 in Chinese healthy volunteers

por Cheung, Tsang Tommy, Luk, Andrea On Yan, Zhang, Yuchen, Pavlovic, Vedran, Wat, Cynthia, Das, Sudip, Surujbally, Bernadette, Triyatni, Miriam, Grippo, Joseph F.
Publicado 2023

A single-dose mass balance and metabolite-profiling study of vemurafenib in patients with metastatic melanoma

por Goldinger, Simone M, Rinderknecht, Jeannine, Dummer, Reinhard, Kuhn, Felix Pierre, Yang, Kuo-Hsiung, Lee, Lucy, Ayala, Ruben C, Racha, Jagdish, Geng, Wanping, Moore, David, Liu, Mei, Joe, Andrew K, Bazan, Selby Patricia Gil, Grippo, Joseph F
Publicado 2015

Clinical Study of Single‐Stranded Oligonucleotide RO7062931 in Healthy Volunteers and Patients With Chronic Hepatitis B

por Gane, Edward, Yuen, Man‐Fung, Kim, Dong Joon, Chan, Henry Lik‐Yuen, Surujbally, Bernadette, Pavlovic, Vedran, Das, Sudip, Triyatni, Miriam, Kazma, Remi, Grippo, Joseph F., Buatois, Simon, Lemenuel‐Diot, Annabelle, Krippendorff, Ben‐Fillippo, Mueller, Henrik, Zhang, Yuchen, Kim, Hyung Joon, Leerapun, Apinya, Lim, Tien Huey, Lim, Young‐Suk, Tanwandee, Tawesak, Kim, Won, Cheng, Wendy, Hu, Tsung‐Hui, Wat, Cynthia
Publicado 2021