Immune modulatory effects of oncogenic KRAS in cancer

por Hamarsheh, Shaima’a, Groß, Olaf, Brummer, Tilman, Zeiser, Robert
Publicado 2020

The Role of Potassium in Inflammasome Activation by Bacteria

por Arlehamn, Cecilia S. Lindestam, Pétrilli, Virginie, Gross, Olaf, Tschopp, Jürg, Evans, Tom J.
Publicado 2010

Sequentially activated death complexes regulate pyroptosis and IL-1β release in response to Yersinia blockade of immune signaling

por Wertman, Ronit Schwartz, Go, Christina K., Saller, Benedikt S., Groß, Olaf, Scott, Phillip, Brodsky, Igor E.
Publicado 2023

The impact of metabolic stressors on mitochondrial homeostasis in a renal epithelial cell model of methylmalonic aciduria

por Schumann, Anke, Brutsche, Marion, Havermans, Monique, Grünert, Sarah C., Kölker, Stefan, Groß, Olaf, Hannibal, Luciana, Spiekerkoetter, Ute
Publicado 2023

Specific Surface Modifications of Silica Nanoparticles Diminish Inflammasome Activation and In Vivo Expression of Selected Inflammatory Genes

por Marzaioli, Viviana, Groß, Christina J., Weichenmeier, Ingrid, Schmidt-Weber, Carsten B., Gutermuth, Jan, Groß, Olaf, Alessandrini, Francesca
Publicado 2017

Piezo1 Channels Contribute to the Regulation of Human Atrial Fibroblast Mechanical Properties and Matrix Stiffness Sensing

por Emig, Ramona, Knodt, Wiebke, Krussig, Mario J., Zgierski-Johnston, Callum M., Gorka, Oliver, Groß, Olaf, Kohl, Peter, Ravens, Ursula, Peyronnet, Rémi
Publicado 2021

Muscle function and homeostasis require cytokine inhibition of AKT activity in Drosophila

por Kierdorf, Katrin, Hersperger, Fabian, Sharrock, Jessica, Vincent, Crystal M, Ustaoglu, Pinar, Dou, Jiawen, Gyoergy, Attila, Groß, Olaf, Siekhaus, Daria E, Dionne, Marc S
Publicado 2020

The adaptor molecule CARD9 is essential for tuberculosis control

por Dorhoi, Anca, Desel, Christiane, Yeremeev, Vladimir, Pradl, Lydia, Brinkmann, Volker, Mollenkopf, Hans-Joachim, Hanke, Karin, Gross, Olaf, Ruland, Jürgen, Kaufmann, Stefan H.E.
Publicado 2010

Lack of Electron Acceptors Contributes to Redox Stress and Growth Arrest in Asparagine-Starved Sarcoma Cells

por Bauer, Christoph, Quante, Meret, Breunis, Willemijn B., Regina, Carla, Schneider, Michaela, Andrieux, Geoffroy, Gorka, Oliver, Groß, Olaf, Boerries, Melanie, Kammerer, Bernd, Hettmer, Simone
Publicado 2021

The fungal peptide toxin Candidalysin activates the NLRP3 inflammasome and causes cytolysis in mononuclear phagocytes

por Kasper, Lydia, König, Annika, Koenig, Paul-Albert, Gresnigt, Mark S., Westman, Johannes, Drummond, Rebecca A., Lionakis, Michail S., Groß, Olaf, Ruland, Jürgen, Naglik, Julian R., Hube, Bernhard
Publicado 2018

An improved organotypic cell culture system to study tissue-resident macrophages ex vivo

por Aktories, Philipp, Petry, Philippe, Glatz, Paulo, Andrieux, Geoffroy, Oschwald, Alexander, Botterer, Hannah, Gorka, Oliver, Erny, Daniel, Boerries, Melanie, Henneke, Philipp, Groß, Olaf, Prinz, Marco, Kierdorf, Katrin
Publicado 2022

Malarial Hemozoin Is a Nalp3 Inflammasome Activating Danger Signal

por Dostert, Catherine, Guarda, Greta, Romero, Jackeline F., Menu, Philippe, Gross, Olaf, Tardivel, Aubry, Suva, Mario-Luca, Stehle, Jean-Christophe, Kopf, Manfred, Stamenkovic, Ivan, Corradin, Giampietro, Tschopp, Jurg
Publicado 2009

Dectin-2 is a Syk-coupled pattern recognition receptor crucial for Th17 responses to fungal infection

por Robinson, Matthew J., Osorio, Fabiola, Rosas, Marcela, Freitas, Rui P., Schweighoffer, Edina, Groß, Olaf, Verbeek, J. Sjef, Ruland, Jürgen, Tybulewicz, Victor, Brown, Gordon D., Moita, Luis Ferreira, Taylor, Philip R., Reis e Sousa, Caetano
Publicado 2009

Functional characterization of the PI3K/AKT/MTOR signaling pathway for targeted therapy in B-precursor acute lymphoblastic leukemia

por Grüninger, Patricia K., Uhl, Franziska, Herzog, Heike, Gentile, Gaia, Andrade-Martinez, Marta, Schmidt, Tobias, Han, Kyuho, Morgens, David W., Bassik, Michael C., Cleary, Michael L., Gorka, Oliver, Zeiser, Robert, Groß, Olaf, Duque-Afonso, Jesús
Publicado 2022

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity

por Schneider, Katharina S., Groß, Christina J., Dreier, Roland F., Saller, Benedikt S., Mishra, Ritu, Gorka, Oliver, Heilig, Rosalie, Meunier, Etienne, Dick, Mathias S., Ćiković, Tamara, Sodenkamp, Jan, Médard, Guillaume, Naumann, Ronald, Ruland, Jürgen, Kuster, Bernhard, Broz, Petr, Groß, Olaf
Publicado 2017

Adjuvanticity of a synthetic cord factor analogue for subunit Mycobacterium tuberculosis vaccination requires FcRγ–Syk–Card9–dependent innate immune activation

por Werninghaus, Kerstin, Babiak, Anna, Groß, Olaf, Hölscher, Christoph, Dietrich, Harald, Agger, Else Marie, Mages, Jörg, Mocsai, Attila, Schoenen, Hanne, Finger, Katrin, Nimmerjahn, Falk, Brown, Gordon D., Kirschning, Carsten, Heit, Antje, Andersen, Peter, Wagner, Hermann, Ruland, Jürgen, Lang, Roland
Publicado 2009

Chemoproteomics‐Enabled Identification of 4‐Oxo‐β‐Lactams as Inhibitors of Dipeptidyl Peptidases 8 and 9

por Carvalho, Luís A. R., Ross, Breyan, Fehr, Lorenz, Bolgi, Oguz, Wöhrle, Svenja, Lum, Kenneth M., Podlesainski, David, Vieira, Andreia C., Kiefersauer, Reiner, Félix, Rita, Rodrigues, Tiago, Lucas, Susana D., Groß, Olaf, Geiss‐Friedlander, Ruth, Cravatt, Benjamin F., Huber, Robert, Kaiser, Markus, Moreira, Rui
Publicado 2022

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy

por Shahzad, Khurrum, Bock, Fabian, Dong, Wei, Wang, Hongjie, Kopf, Stefan, Kohli, Shrey, Al-Dabet, Moh'd Mohanad, Ranjan, Satish, Wolter, Juliane, Wacker, Christian, Biemann, Ronald, Stoyanov, Stoyan, Reymann, Klaus, Söderkvist, Peter, Groß, Olaf, Schwenger, Vedat, Pahernik, Sascha, Nawroth, Peter P, Gröne, Herman-Josef, Madhusudhan, Thati, Isermann, Berend
Publicado 2015

Human T(H)17 cells engage gasdermin E pores to release IL-1α on NLRP3 inflammasome activation

por Chao, Ying-Yin, Puhach, Alisa, Frieser, David, Arunkumar, Mahima, Lehner, Laurens, Seeholzer, Thomas, Garcia-Lopez, Albert, van der Wal, Marlot, Fibi-Smetana, Silvia, Dietschmann, Axel, Sommermann, Thomas, Ćiković, Tamara, Taher, Leila, Gresnigt, Mark S., Vastert, Sebastiaan J., van Wijk, Femke, Panagiotou, Gianni, Krappmann, Daniel, Groß, Olaf, Zielinski, Christina E.
Publicado 2023

Prdm6 Is Essential for Cardiovascular Development In Vivo

por Gewies, Andreas, Castineiras-Vilarino, Mercedes, Ferch, Uta, Jährling, Nina, Heinrich, Katja, Hoeckendorf, Ulrike, Przemeck, Gerhard K. H., Munding, Matthias, Groß, Olaf, Schroeder, Timm, Horsch, Marion, Karran, E. Loraine, Majid, Aneela, Antonowicz, Stefan, Beckers, Johannes, Hrabé de Angelis, Martin, Dodt, Hans-Ulrich, Peschel, Christian, Förster, Irmgard, Dyer, Martin J. S., Ruland, Jürgen
Publicado 2013