Hemoprotein Catalyzed Oxygenations: P450s, UPOs, and Progress toward Scalable Reactions

por Grogan, Gideon
Publicado 2021

Structure and Mutation of the Native Amine Dehydrogenase MATOUAmDH2

por Bennett, Megan, Ducrot, Laurine, Vergne‐Vaxelaire, Carine, Grogan, Gideon
Publicado 2022

Mutations of an NAD(P)H-dependent flavoprotein monooxygenase that influence cofactor promiscuity and enantioselectivity()

por Jensen, Chantel N., Ali, Sohail T., Allen, Michael J., Grogan, Gideon
Publicado 2013

Exploring nicotinamide cofactor promiscuity in NAD(P)H-dependent flavin containing monooxygenases (FMOs) using natural variation within the phosphate binding loop. Structure and ac...

por Jensen, Chantel N., Ali, Sohail T., Allen, Michael J., Grogan, Gideon
Publicado 2014

NAD(P)H‐Dependent Dehydrogenases for the Asymmetric Reductive Amination of Ketones: Structure, Mechanism, Evolution and Application

por Sharma, Mahima, Mangas‐Sanchez, Juan, Turner, Nicholas J., Grogan, Gideon
Publicado 2017

Reductive aminations by imine reductases: from milligrams to tons

por Gilio, Amelia K., Thorpe, Thomas W., Turner, Nicholas, Grogan, Gideon
Publicado 2022

Structure of the imine reductase from Ajellomyces dermatitidis in three crystal forms

por Sharma, Mahima, Cuetos, Anibal, Willliams, Adam, González-Martínez, Daniel, Grogan, Gideon
Publicado 2023

Characterization and structure‐guided engineering of the novel versatile terpene monooxygenase CYP109Q5 from Chondromyces apiculatus DSM436

por Klenk, Jan M., Dubiel, Paulina, Sharma, Mahima, Grogan, Gideon, Hauer, Bernhard
Publicado 2018

Artificial imine reductases: developments and future directions

por Booth, Rosalind L., Grogan, Gideon, Wilson, Keith S., Duhme-Klair, Anne-Kathrin
Publicado 2020

Structural evidence for Arabidopsis glutathione transferase AtGSTF2 functioning as a transporter of small organic ligands

por Ahmad, Laziana, Rylott, Elizabeth L., Bruce, Neil C., Edwards, Robert, Grogan, Gideon
Publicado 2016

Advanced Insights into Catalytic and Structural Features of the Zinc‐Dependent Alcohol Dehydrogenase from Thauera aromatica

por Stark, Frances, Loderer, Christoph, Petchey, Mark, Grogan, Gideon, Ansorge‐Schumacher, Marion B.
Publicado 2022

Oxalate Oxidase for In Situ H(2)O(2)‐Generation in Unspecific Peroxygenase‐Catalysed Drug Oxyfunctionalisations

por Romero, Elvira, Johansson, Magnus J., Cartwright, Jared, Grogan, Gideon, Hayes, Martin A.
Publicado 2022

Biocatalytic Synthesis of Moclobemide Using the Amide Bond Synthetase McbA Coupled with an ATP Recycling System

por Petchey, Mark R., Rowlinson, Benjamin, Lloyd, Richard C., Fairlamb, Ian J. S., Grogan, Gideon
Publicado 2020

Preparative‐Scale Biocatalytic Oxygenation of N‐Heterocycles with a Lyophilized Peroxygenase Catalyst

por Pogrányi, Balázs, Mielke, Tamara, Díaz‐Rodríguez, Alba, Cartwright, Jared, Unsworth, William P., Grogan, Gideon
Publicado 2022

Biocatalytic Conversion of Cyclic Ketones Bearing α‐Quaternary Stereocenters into Lactones in an Enantioselective Radical Approach to Medium‐Sized Carbocycles

por Morrill, Charlotte, Jensen, Chantel, Just‐Baringo, Xavier, Grogan, Gideon, Turner, Nicholas J., Procter, David J.
Publicado 2018

Structure-Guided Mechanisms Behind the Metabolism of 2,4,6-Trinitrotoluene by Glutathione Transferases U25 and U24 That Lead to Alternate Product Distribution

por Tzafestas, Kyriakos, Ahmad, Laziana, Dani, M. Paulina, Grogan, Gideon, Rylott, Elizabeth L., Bruce, Neil C.
Publicado 2018

Inverting the Stereoselectivity of an NADH‐Dependent Imine‐Reductase Variant

por Stockinger, Peter, Borlinghaus, Niels, Sharma, Mahima, Aberle, Benjamin, Grogan, Gideon, Pleiss, Jürgen, Nestl, Bettina M.
Publicado 2021

Regio- and stereoselective oxidation of unactivated C–H bonds with Rhodococcus rhodochrous

por O’Reilly, Elaine, Aitken, Suzanne J, Grogan, Gideon, Kelly, Paul P, Turner, Nicholas J, Flitsch, Sabine L
Publicado 2012

Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet–Spengler Reactions

por Eger, Elisabeth, Simon, Adam, Sharma, Mahima, Yang, Song, Breukelaar, Willem B., Grogan, Gideon, Houk, K. N., Kroutil, Wolfgang
Publicado 2020

Correction to “Inverted Binding of Non-natural Substrates in Strictosidine Synthase Leads to a Switch of Stereochemical Outcome in Enzyme-Catalyzed Pictet–Spengler Reactions”

por Eger, Elisabeth, Simon, Adam, Sharma, Mahima, Yang, Song, Breukelaar, Willem B., Grogan, Gideon, Houk, K. N., Kroutil, Wolfgang
Publicado 2020