The Effect of Antifibrotic Drugs in Rat Precision-Cut Fibrotic Liver Slices

por Westra, Inge M., Oosterhuis, Dorenda, Groothuis, Geny M. M., Olinga, Peter
Publicado 2014

Validation of precision-cut liver slices to study drug-induced cholestasis: a transcriptomics approach

por Vatakuti, Suresh, Olinga, Peter, Pennings, Jeroen L. A., Groothuis, Geny M. M.
Publicado 2016

Bronchoconstriction Induces TGF-β Release and Airway Remodelling in Guinea Pig Lung Slices

por Oenema, Tjitske A., Maarsingh, Harm, Smit, Marieke, Groothuis, Geny M. M., Meurs, Herman, Gosens, Reinoud
Publicado 2013

Maintenance of drug metabolism and transport functions in human precision-cut liver slices during prolonged incubation for 5 days

por Starokozhko, Viktoriia, Vatakuti, Suresh, Schievink, Bauke, Merema, Marjolijn T., Asplund, Annika, Synnergren, Jane, Aspegren, Anders, Groothuis, Geny M. M.
Publicado 2016

Rat precision-cut liver slices predict drug-induced cholestatic injury

por Starokozhko, Viktoriia, Greupink, Rick, van de Broek, Petra, Soliman, Nashwa, Ghimire, Samiksha, de Graaf, Inge A. M., Groothuis, Geny M. M.
Publicado 2017

Differentiation of human‐induced pluripotent stem cell under flow conditions to mature hepatocytes for liver tissue engineering

por Starokozhko, Viktoriia, Hemmingsen, Mette, Larsen, Layla, Mohanty, Soumyaranjan, Merema, Marjolijn, Pimentel, Rodrigo C., Wolff, Anders, Emnéus, Jenny, Aspegren, Anders, Groothuis, Geny, Dufva, Martin
Publicado 2018

Mechanism-Based Pharmacokinetic–Pharmacodynamic Modeling of the Dopamine D(2) Receptor Occupancy of Olanzapine in Rats

por Johnson, Martin, Kozielska, Magdalena, Pilla Reddy, Venkatesh, Vermeulen, An, Li, Cheryl, Grimwood, Sarah, de Greef, Rik, Groothuis, Geny M. M., Danhof, Meindert, Proost, Johannes H.
Publicado 2011

Comparative analysis of the human hepatic and adipose tissue transcriptomes during LPS-induced inflammation leads to the identification of differential biological pathways and cand...

por Szalowska, Ewa, Dijkstra, Martijn, Elferink, Marieke GL, Weening, Desiree, de Vries, Marcel, Bruinenberg, Marcel, Hoek, Annemieke, Roelofsen, Han, Groothuis, Geny MM, Vonk, Roel J
Publicado 2011

Pharmacokinetic-Pharmacodynamic Modeling of the D(2) and 5-HT(2A) Receptor Occupancy of Risperidone and Paliperidone in Rats

por Kozielska, Magdalena, Johnson, Martin, Pilla Reddy, Venkatesh, Vermeulen, An, Li, Cheryl, Grimwood, Sarah, de Greef, Rik, Groothuis, Geny M. M., Danhof, Meindert, Proost, Johannes H.
Publicado 2012

Erratum to: Translational Modeling in Schizophrenia: Predicting Human Dopamine D(2) Receptor Occupancy

por Johnson, Martin, Kozielska, Magdalena, Pilla Reddy, Venkatesh, Vermeulen, An, Barton, Hugh A., Grimwood, Sarah, de Greef, Rik, Groothuis, Geny M. M., Danhof, Meindert, Proost, Johannes H.
Publicado 2016

Disruption of vitamin A homeostasis by the biocide tetrakis(hydroxymethyl) phosphonium sulphate in pregnant rabbits

por Estrada‐Ortiz, Natalia, Starokozhko, Viktoriia, van Steenwijk, Hidde, van der Heide, Cor, Permentier, Hjalmar, van Heemskerk, Lisanne, Prins, Grietje Harmanna, Heegsma, Janette, Faber, Klaas Nico, Bressers, Steffi, Steiblen, Guy, de Groot, Antoinette, Groome, Steve, van Miert, Erik, Groothuis, Geny, de Graaf, Inge Anne Maria
Publicado 2022

Recent advances in 2D and 3D in vitro systems using primary hepatocytes, alternative hepatocyte sources and non-parenchymal liver cells and their use in investigating mechanisms of...

por Godoy, Patricio, Hewitt, Nicola J., Albrecht, Ute, Andersen, Melvin E., Ansari, Nariman, Bhattacharya, Sudin, Bode, Johannes Georg, Bolleyn, Jennifer, Borner, Christoph, Böttger, Jan, Braeuning, Albert, Budinsky, Robert A., Burkhardt, Britta, Cameron, Neil R., Camussi, Giovanni, Cho, Chong-Su, Choi, Yun-Jaie, Craig Rowlands, J., Dahmen, Uta, Damm, Georg, Dirsch, Olaf, Donato, María Teresa, Dong, Jian, Dooley, Steven, Drasdo, Dirk, Eakins, Rowena, Ferreira, Karine Sá, Fonsato, Valentina, Fraczek, Joanna, Gebhardt, Rolf, Gibson, Andrew, Glanemann, Matthias, Goldring, Chris E. P., Gómez-Lechón, María José, Groothuis, Geny M. M., Gustavsson, Lena, Guyot, Christelle, Hallifax, David, Hammad, Seddik, Hayward, Adam, Häussinger, Dieter, Hellerbrand, Claus, Hewitt, Philip, Hoehme, Stefan, Holzhütter, Hermann-Georg, Houston, J. Brian, Hrach, Jens, Ito, Kiyomi, Jaeschke, Hartmut, Keitel, Verena, Kelm, Jens M., Kevin Park, B., Kordes, Claus, Kullak-Ublick, Gerd A., LeCluyse, Edward L., Lu, Peng, Luebke-Wheeler, Jennifer, Lutz, Anna, Maltman, Daniel J., Matz-Soja, Madlen, McMullen, Patrick, Merfort, Irmgard, Messner, Simon, Meyer, Christoph, Mwinyi, Jessica, Naisbitt, Dean J., Nussler, Andreas K., Olinga, Peter, Pampaloni, Francesco, Pi, Jingbo, Pluta, Linda, Przyborski, Stefan A., Ramachandran, Anup, Rogiers, Vera, Rowe, Cliff, Schelcher, Celine, Schmich, Kathrin, Schwarz, Michael, Singh, Bijay, Stelzer, Ernst H. K., Stieger, Bruno, Stöber, Regina, Sugiyama, Yuichi, Tetta, Ciro, Thasler, Wolfgang E., Vanhaecke, Tamara, Vinken, Mathieu, Weiss, Thomas S., Widera, Agata, Woods, Courtney G., Xu, Jinghai James, Yarborough, Kathy M., Hengstler, Jan G.
Publicado 2013