Pdc2/Pat1 increases the range of decay factors and RNA bound by the Lsm1–7 complex

por Lobel, Joseph H., Gross, John D.
Publicado 2020

Biophysical Properties of HP1-Mediated Heterochromatin

por Sanulli, Serena, Gross, John D., Narlikar, Geeta J.
Publicado 2019

Structural basis of mRNA cap recognition by Dcp1–Dcp2

por Mugridge, Jeffrey S, Ziemniak, Marcin, Jemielity, Jacek, Gross, John D
Publicado 2016

Application of a Schizosaccharomyces pombe Edc1-fused Dcp1–Dcp2 decapping enzyme for transcription start site mapping

por Paquette, David R., Mugridge, Jeffrey S., Weinberg, David E., Gross, John D.
Publicado 2018

Control of mRNA decapping by autoinhibition

por Paquette, David R, Tibble, Ryan W, Daifuku, Tristan S, Gross, John D
Publicado 2018

A split active site couples cap recognition by Dcp2 to activation

por Floor, Stephen N., Jones, Brittnee N., Hernandez, Gail A., Gross, John D.
Publicado 2010

Structure of the activated Edc1-Dcp1-Dcp2-Edc3 mRNA decapping complex with substrate analog poised for catalysis

por Mugridge, Jeffrey S., Tibble, Ryan W., Ziemniak, Marcin, Jemielity, Jacek, Gross, John D.
Publicado 2018

Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation

por Tibble, Ryan W., Depaix, Anaïs, Kowalska, Joanna, Jemielity, Jacek, Gross, John D.
Publicado 2021

Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex

por Ziemniak, Marcin, Mugridge, Jeffrey S., Kowalska, Joanna, Rhoads, Robert E., Gross, John D., Jemielity, Jacek
Publicado 2016

The glucocorticoid receptor dimer interface allosterically transmits sequence-specific DNA signals

por Watson, Lisa C., Kuchenbecker, Kristopher M., Schiller, Benjamin J., Gross, John D., Pufall, Miles A., Yamamoto, Keith R.
Publicado 2013

The structural basis for HIV-1 Vif antagonism of human APOBEC3G

por Li, Yen-Li, Langley, Caroline A., Azumaya, Caleigh M., Echeverria, Ignacia, Chesarino, Nicholas M., Emerman, Michael, Cheng, Yifan, Gross, John D.
Publicado 2023

Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-...

por Warminski, Marcin, Kowalska, Joanna, Nowak, Elzbieta, Kubacka, Dorota, Tibble, Ryan, Kasprzyk, Renata, Sikorski, Pawel J., Gross, John D., Nowotny, Marcin, Jemielity, Jacek
Publicado 2021

Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9

por Bednarczyk, Marcelina, Peters, Jessica K., Kasprzyk, Renata, Starek, Jagoda, Warminski, Marcin, Spiewla, Tomasz, Mugridge, Jeffrey S., Gross, John D., Jemielity, Jacek, Kowalska, Joanna
Publicado 2022

Identification of recombinant Fabs for structural and functional characterization of HIV-host factor complexes

por Sevillano, Natalia, Green, Evan M., Votteler, Jörg, Kim, Dong Young, Ren, Xuefeng, Yang, Bei, Liu, Xi, Lourenço, André Luiz, Hurley, James H., Farr-Jones, Shauna, Gross, John D., Cheng, Yifan, Craik, Charles S.
Publicado 2021

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

por Walter, Marius, Chen, Irene P, Vallejo-Gracia, Albert, Kim, Ik-Jung, Bielska, Olga, Lam, Victor L, Hayashi, Jennifer M, Cruz, Andrew, Shah, Samah, Gross, John D, Krogan, Nevan J, Schilling, Birgit, Ott, Melanie, Verdin, Eric
Publicado 2022

Inhibition of a NEDD8 Cascade Restores Restriction of HIV by APOBEC3G

por Stanley, David J., Bartholomeeusen, Koen, Crosby, David C., Kim, Dong Young, Kwon, Eunju, Yen, Linda, Cartozo, Nathalie Caretta, Li, Ming, Jäger, Stefanie, Mason-Herr, Jeremy, Hayashi, Fumiaki, Yokoyama, Shigeyuki, Krogan, Nevan J., Harris, Reuben S., Peterlin, Boris Matija, Gross, John D.
Publicado 2012

SIRT5 is a proviral factor that interacts with SARS-CoV-2 Nsp14 protein

por Walter, Marius, Chen, Irene P., Vallejo-Gracia, Albert, Kim, Ik-Jung, Bielska, Olga, Lam, Victor L., Hayashi, Jennifer M., Cruz, Andrew, Shah, Samah, Soveg, Frank W., Gross, John D., Krogan, Nevan J., Jerome, Keith R., Schilling, Birgit, Ott, Melanie, Verdin, Eric
Publicado 2022

Fab-based inhibitors reveal ubiquitin independent functions for HIV Vif neutralization of APOBEC3 restriction factors

por Binning, Jennifer M., Smith, Amber M., Hultquist, Judd F., Craik, Charles S., Caretta Cartozo, Nathalie, Campbell, Melody G., Burton, Lily, La Greca, Florencia, McGregor, Michael J., Ta, Hai M., Bartholomeeusen, Koen, Peterlin, B. Matija, Krogan, Nevan J., Sevillano, Natalia, Cheng, Yifan, Gross, John D.
Publicado 2018

A SARS-CoV-2 Protein Interaction Map Reveals Targets for Drug-Repurposing

por Gordon, David E., Jang, Gwendolyn M., Bouhaddou, Mehdi, Xu, Jiewei, Obernier, Kirsten, White, Kris M., O’Meara, Matthew J., Rezelj, Veronica V., Guo, Jeffrey Z., Swaney, Danielle L., Tummino, Tia A., Huettenhain, Ruth, Kaake, Robyn M., Richards, Alicia L., Tutuncuoglu, Beril, Foussard, Helene, Batra, Jyoti, Haas, Kelsey, Modak, Maya, Kim, Minkyu, Haas, Paige, Polacco, Benjamin J., Braberg, Hannes, Fabius, Jacqueline M., Eckhardt, Manon, Soucheray, Margaret, Bennett, Melanie J., Cakir, Merve, McGregor, Michael J., Li, Qiongyu, Meyer, Bjoern, Roesch, Ferdinand, Vallet, Thomas, Kain, Alice Mac, Miorin, Lisa, Moreno, Elena, Naing, Zun Zar Chi, Zhou, Yuan, Peng, Shiming, Shi, Ying, Zhang, Ziyang, Shen, Wenqi, Kirby, Ilsa T., Melnyk, James E., Chorba, John S., Lou, Kevin, Dai, Shizhong A., Barrio-Hernandez, Inigo, Memon, Danish, Hernandez-Armenta, Claudia, Lyu, Jiankun, Mathy, Christopher J.P., Perica, Tina, Pilla, Kala B., Ganesan, Sai J., Saltzberg, Daniel J., Rakesh, Ramachandran, Liu, Xi, Rosenthal, Sara B., Calviello, Lorenzo, Venkataramanan, Srivats, Liboy-Lugo, Jose, Lin, Yizhu, Huang, Xi-Ping, Liu, YongFeng, Wankowicz, Stephanie A., Bohn, Markus, Safari, Maliheh, Ugur, Fatima S., Koh, Cassandra, Savar, Nastaran Sadat, Tran, Quang Dinh, Shengjuler, Djoshkun, Fletcher, Sabrina J, O’Neal, Michael C., Cai, Yiming, C.J.Chang, Jason, Broadhurst, David J., Klippsten, Saker, Sharp, Phillip P., Wenzell, Nicole A., Kuzuoglu, Duygu, Wang, Hao-Yuan, Trenker, Raphael, Young, Janet M., Cavero, Devin A., Hiatt, Joseph, Roth, Theodore L., Rathore, Ujjwal, Subramanian, Advait, Noack, Julia, Hubert, Mathieu, Stroud, Robert M., Frankel, Alan D., Rosenberg, Oren S., Verba, Kliment A, Agard, David A., Ott, Melanie, Emerman, Michael, Jura, Natalia, von Zastrow, Mark, Verdin, Eric, Ashworth, Alan, Schwartz, Olivier, d’Enfert, Christophe, Mukherjee, Shaeri, Jacobson, Matt, Malik, Harmit S., Fujimori, Danica G., Ideker, Trey, Craik, Charles S., Floor, Stephen N., Fraser, James S., Gross, John D., Sali, Andrej, Roth, Bryan L., Ruggero, Davide, Taunton, Jack, Kortemme, Tanja, Beltrao, Pedro, Vignuzzi, Marco, García-Sastre, Adolfo, Shokat, Kevan M., Shoichet, Brian K., Krogan, Nevan J.
Publicado 2020