An interplay of miRNA abundance and target site architecture determines miRNA activity and specificity

por Brancati, Giovanna, Großhans, Helge
Publicado 2018

Micro-RNAs: small is plentiful

por Grosshans, Helge, Slack, Frank J.
Publicado 2002

The type II poly(A)-binding protein PABP-2 genetically interacts with the let-7 miRNA and elicits heterochronic phenotypes in Caenorhabditis elegans

por Hurschler, Benjamin A., Harris, David T., Großhans, Helge
Publicado 2011

Two distinct transcription termination modes dictated by promoters

por Miki, Takashi S., Carl, Sarah H., Großhans, Helge
Publicado 2017

Coupling of growth rate and developmental tempo reduces body size heterogeneity in C. elegans

por Stojanovski, Klement, Großhans, Helge, Towbin, Benjamin D.
Publicado 2022

Biogenesis of the Signal Recognition Particle (Srp) Involves Import of Srp Proteins into the Nucleolus, Assembly with the Srp-Rna, and Xpo1p-Mediated Export

por Grosshans, Helge, Deinert, Karina, Hurt, Ed, Simos, George
Publicado 2001

The ribonucleotidyl transferase USIP-1 acts with SART3 to promote U6 snRNA recycling

por Rüegger, Stefan, Miki, Takashi S., Hess, Daniel, Großhans, Helge
Publicado 2015

Structural Basis and Function of XRN2-Binding by XTB Domains

por Richter, Hannes, Katic, Iskra, Gut, Heinz, Großhans, Helge
Publicado 2016

let-7 coordinates the transition to adulthood through a single primary and four secondary targets

por Aeschimann, Florian, Neagu, Anca, Rausch, Magdalene, Großhans, Helge
Publicado 2019

A branched heterochronic pathway directs juvenile-to-adult transition through two LIN-29 isoforms

por Azzi, Chiara, Aeschimann, Florian, Neagu, Anca, Großhans, Helge
Publicado 2020

The nuclear export receptor XPO-1 supports primary miRNA processing in C. elegans and Drosophila

por Büssing, Ingo, Yang, Jr-Shiuan, Lai, Eric C, Großhans, Helge
Publicado 2010

XRN2 Autoregulation and Control of Polycistronic Gene Expresssion in Caenorhabditis elegans

por Miki, Takashi S., Carl, Sarah H., Stadler, Michael B., Großhans, Helge
Publicado 2016

Engineering of a conditional allele reveals multiple roles of XRN2 in Caenorhabditis elegans development and substrate specificity in microRNA turnover

por Miki, Takashi S., Rüegger, Stefan, Gaidatzis, Dimos, Stadler, Michael B., Großhans, Helge
Publicado 2014

Bayesian prediction of RNA translation from ribosome profiling

por Malone, Brandon, Atanassov, Ilian, Aeschimann, Florian, Li, Xinping, Großhans, Helge, Dieterich, Christoph
Publicado 2017

Timing mechanism of sexually dimorphic nervous system differentiation

por Pereira, Laura, Aeschimann, Florian, Wang, Chen, Lawson, Hannah, Serrano-Saiz, Esther, Portman, Douglas S, Großhans, Helge, Hobert, Oliver
Publicado 2019

The RNA hairpin binder TRIM71 modulates alternative splicing by repressing MBNL1

por Welte, Thomas, Tuck, Alex C., Papasaikas, Panagiotis, Carl, Sarah H., Flemr, Matyas, Knuckles, Philip, Rankova, Aneliya, Bühler, Marc, Großhans, Helge
Publicado 2019

C. elegans molting requires rhythmic accumulation of the Grainyhead/LSF transcription factor GRH‐1

por Meeuse, Milou W M, Hauser, Yannick P, Nahar, Smita, Smith, A Alexander T, Braun, Kathrin, Azzi, Chiara, Rempfler, Markus, Großhans, Helge
Publicado 2023

Developmental function and state transitions of a gene expression oscillator in Caenorhabditis elegans

por Meeuse, Milou WM, Hauser, Yannick P, Morales Moya, Lucas J, Hendriks, Gert‐Jan, Eglinger, Jan, Bogaarts, Guy, Tsiairis, Charisios, Großhans, Helge
Publicado 2020

H3K9me selectively blocks transcription factor activity and ensures differentiated tissue integrity

por Methot, Stephen P., Padeken, Jan, Brancati, Giovanna, Zeller, Peter, Delaney, Colin E., Gaidatzis, Dimos, Kohler, Hubertus, van Oudenaarden, Alexander, Großhans, Helge, Gasser, Susan M.
Publicado 2021

Evolutionary plasticity of the NHL domain underlies distinct solutions to RNA recognition

por Kumari, Pooja, Aeschimann, Florian, Gaidatzis, Dimos, Keusch, Jeremy J., Ghosh, Pritha, Neagu, Anca, Pachulska-Wieczorek, Katarzyna, Bujnicki, Janusz M., Gut, Heinz, Großhans, Helge, Ciosk, Rafal
Publicado 2018