Multiple sclerosis pharmacogenetics: personalized approach towards tailored therapeutics

por Grossman, Iris, Miller, Ariel
Publicado 2010

Overcoming a species-specificity barrier in development of an inhibitory antibody targeting a modulator of tumor stroma

por Grossman, Iris, Ilani, Tal, Fleishman, Sarel Jacob, Fass, Deborah
Publicado 2016

Biobanking in Israel 2016–17; expressed perceptions versus real life enrollment

por Koren, Gideon, Beller, Daniella, Laifenfeld, Daphna, Grossman, Iris, Shalev, Varda
Publicado 2017

Trick or treat: The effect of placebo on the power of pharmacogenetic association studies

por Singer, Clara, Grossman, Iris, Avidan, Nili, Beckmann, Jacques S, Pe'er, Itsik
Publicado 2005

Single-molecule spectroscopy exposes hidden states in an enzymatic electron relay

por Grossman, Iris, Yuval Aviram, Haim, Armony, Gad, Horovitz, Amnon, Hofmann, Hagen, Haran, Gilad, Fass, Deborah
Publicado 2015

Alzheimer’s disease: diagnostics, prognostics and the road to prevention

por Grossman, Iris, Lutz, Michael W., Crenshaw, Donna G., Saunders, Ann M., Burns, Daniel K., Roses, Allen D.
Publicado 2010

Emulated Clinical Trials from Longitudinal Real-World Data Efficiently Identify Candidates for Neurological Disease Modification: Examples from Parkinson’s Disease

por Laifenfeld, Daphna, Yanover, Chen, Ozery-Flato, Michal, Shaham, Oded, Rosen-Zvi, Michal, Lev, Nirit, Goldschmidt, Yaara, Grossman, Iris
Publicado 2021

Characterizing patient compliance over six months in remote digital trials of Parkinson’s and Huntington disease

por Cohen, Shani, Waks, Zeev, Elm, Jordan J., Gordon, Mark Forrest, Grachev, Igor D., Navon-Perry, Leehee, Fine, Shai, Grossman, Iris, Papapetropoulos, Spyros, Savola, Juha-Matti
Publicado 2018

A pharmacogenetic signature of high response to Copaxone in late-phase clinical-trial cohorts of multiple sclerosis

por Ross, Colin J., Towfic, Fadi, Shankar, Jyoti, Laifenfeld, Daphna, Thoma, Mathis, Davis, Matthew, Weiner, Brian, Kusko, Rebecca, Zeskind, Ben, Knappertz, Volker, Grossman, Iris, Hayden, Michael R.
Publicado 2017

Discovery and Targeting of the Signaling Controls of PNPLA3 to Effectively Reduce Transcription, Expression, and Function in Pre-Clinical NAFLD/NASH Settings

por Schwartz, Brian E., Rajagopal, Vaishnavi, Smith, Cynthia, Cohick, Evan, Whissell, Gavin, Gamboa, Mario, Pai, Rutuja, Sigova, Alla, Grossman, Iris, Bumcrot, David, Sasidharan, Kavitha, Romeo, Stefano, Sehgal, Alfica, Pingitore, Piero
Publicado 2020

Large-scale transcriptomic analysis reveals that pridopidine reverses aberrant gene expression and activates neuroprotective pathways in the YAC128 HD mouse

por Kusko, Rebecca, Dreymann, Jennifer, Ross, Jermaine, Cha, Yoonjeong, Escalante-Chong, Renan, Garcia-Miralles, Marta, Tan, Liang Juin, Burczynski, Michael E., Zeskind, Ben, Laifenfeld, Daphna, Pouladi, Mahmoud, Geva, Michal, Grossman, Iris, Hayden, Michael R.
Publicado 2018

Gene expression studies of a human monocyte cell line identify dissimilarities between differently manufactured glatiramoids

por Kolitz, Sarah, Hasson, Tal, Towfic, Fadi, Funt, Jason M., Bakshi, Shlomo, Fowler, Kevin D., Laifenfeld, Daphna, Grinspan, Augusto, Artyomov, Maxim N., Birnberg, Tal, Schwartz, Rivka, Komlosh, Arthur, Hayardeny, Liat, Ladkani, David, Hayden, Michael R., Zeskind, Benjamin, Grossman, Iris
Publicado 2015

Response to the Letter-to-the Editor by Cohen et al. concerning our eNeurologicalSci article, Melamed-Gal, et al. Physicochemical, biological, functional and toxicological characte...

por Melamed-Gal, Sigal, Loupe, Pippa, Timan, Bracha, Weinstein, Vera, Kolitz, Sarah, Zhang, Jenny, Funt, Jason, Komlosh, Arthur, Ashkenazi, Nurit, Bar-Ilan, Oren, Konya, Attila, Beriozkin, Olga, Laifenfeld, Daphna, Hasson, Tal, Zeskind, Benjamin, Hayden, Michael, Nock, Steffen, Grossman, Iris
Publicado 2018

Pridopidine activates neuroprotective pathways impaired in Huntington Disease

por Geva, Michal, Kusko, Rebecca, Soares, Holly, Fowler, Kevin D., Birnberg, Tal, Barash, Steve, -Wagner, Avia Merenlender, Fine, Tania, Lysaght, Andrew, Weiner, Brian, Cha, Yoonjeong, Kolitz, Sarah, Towfic, Fadi, Orbach, Aric, Laufer, Ralph, Zeskind, Ben, Grossman, Iris, Hayden, Michael R.
Publicado 2016

Characterization of the Poly-T Variant in the TOMM40 Gene in Diverse Populations

por Linnertz, Colton, Saunders, Ann M., Lutz, Michael W., Crenshaw, Donna M., Grossman, Iris, Burns, Daniel K., Whitfield, Keith E., Hauser, Michael A., McCarthy, Jeanette J., Ulmer, Megan, Allingham, Rand, Welsh-Bohmer, Kathleen A., Roses, Allen D., Chiba-Falek, Ornit
Publicado 2012

Genome wide screen of RNAi molecules against SARS-CoV-2 creates a broadly potent prophylaxis

por Yogev, Ohad, Weissbrod, Omer, Battistoni, Giorgia, Bressan, Dario, Naamti, Adi, Falciatori, Ilaria, Berkyurek, Ahmet C., Rasnic, Roni, Hosmillo, Myra, Ilan, Shaul, Grossman, Iris, McCormick, Lauren, Honeycutt, Christopher C., Johnston, Timothy, Gagne, Matthew, Douek, Daniel C., Goodfellow, Ian, Hannon, Gregory J., Erlich, Yaniv
Publicado 2022

From a genome-wide screen of RNAi molecules against SARS-CoV-2 to a validated broad-spectrum and potent prophylaxis

por Yogev, Ohad, Weissbrod, Omer, Battistoni, Giorgia, Bressan, Dario, Naamati, Adi, Falciatori, Ilaria, Berkyurek, Ahmet Can, Rasnic, Roni, Izuagbe, Rhys, Hosmillo, Myra, Ilan, Shaul, Grossman, Iris, McCormick, Lauren, Honeycutt, Christopher Cole, Johnston, Timothy, Gagne, Matthew, Douek, Daniel C, Goodfellow, Ian, Hannon, Gregory James, Erlich, Yaniv
Publicado 2023