NIAM’s tangled web of growth control

por Love, Ian M, Grossman, Steven R
Publicado 2014

Harnessing the vulnerabilities of p53 mutants in lung cancer – Focusing on the proteasome: a new trick for an old foe?

por Oduah, Eziafa I., Grossman, Steven R.
Publicado 2020

Extraction of high-quality RNA from mouse pancreatic tumors

por Chougoni, Kranthi Kumar, Grossman, Steven R.
Publicado 2020

CtBP- an emerging oncogene and novel small molecule drug target: Advances in the understanding of its oncogenic action and identification of therapeutic inhibitors

por Dcona, M. Michael, Morris, Benjamin L., Ellis, Keith C., Grossman, Steven R.
Publicado 2017

CtBP determines ovarian cancer cell fate through repression of death receptors

por Ding, Boxiao, Yuan, Fang, Damle, Priyadarshan K., Litovchick, Larisa, Drapkin, Ronny, Grossman, Steven R.
Publicado 2020

The SWI/SNF chromatin remodeling subunit BRG1 is a critical regulator of p53 necessary for proliferation of malignant cells

por Naidu, Samisubbu R., Love, Ian M., Imbalzano, Anthony N., Grossman, Steven R., Androphy, Elliot J.
Publicado 2009

Gain‐of‐function p53 activates multiple signaling pathways to induce oncogenicity in lung cancer cells

por Vaughan, Catherine A., Singh, Shilpa, Grossman, Steven R., Windle, Brad, Deb, Swati Palit, Deb, Sumitra
Publicado 2017

Combined Targeting of NAD Biosynthesis and the NAD-dependent Transcription Factor C-terminal Binding Protein as a Promising Novel Therapy for Pancreatic Cancer

por Dcona, M. Michael, Chougoni, Kranthi Kumar, Dcona, Diana T., West, Jacqueline L., Singh, Sahib J., Ellis, Keith C., Grossman, Steven R.
Publicado 2023

The human oncoprotein MDM2 induces replication stress eliciting early intra-S-phase checkpoint response and inhibition of DNA replication origin firing

por Frum, Rebecca A., Singh, Shilpa, Vaughan, Catherine, Mukhopadhyay, Nitai D., Grossman, Steven R., Windle, Brad, Deb, Sumitra, Deb, Swati Palit
Publicado 2014

Addiction of lung cancer cells to GOF p53 is promoted by up-regulation of epidermal growth factor receptor through multiple contacts with p53 transactivation domain and promoter

por Vaughan, Catherine A., Pearsall, Isabella, Singh, Shilpa, Windle, Brad, Deb, Swati P., Grossman, Steven R., Yeudall, W. Andrew, Deb, Sumitra
Publicado 2016

DBC1 Regulates p53 Stability via Inhibition of CBP-Dependent p53 Polyubiquitination

por Akande, Oluwatoyin E., Damle, Priyadarshan K., Pop, Marius, Sherman, Nicholas E., Szomju, Barbara B., Litovchick, Larisa V., Grossman, Steven R.
Publicado 2019

An intestinal stem cell niche in Apc mutated neoplasia targetable by CtBP inhibition

por Chawla, Ayesha T., Cororaton, Agnes D., Idowu, Michael O., Damle, Priyadarshan K., Szomju, Barbara, Ellis, Keith C., Patel, Bhaumik B., Grossman, Steven R.
Publicado 2018

Phase 1 Study of Neoadjuvant Short-Course Radiation Therapy Concurrent With Infusional 5-Fluorouracil for the Treatment of Locally Advanced Rectal Cancer

por Fields, Emma C., Kaplan, Brian J., Karlin, Jeremy, Myers, Jennifer L., Mukhopadhyay, Nitai, Deng, Xiaoyan, Sankala, Heidi, Grossman, Steven R., Matin, Khalid
Publicado 2019

Clinical Activity and Safety of Cediranib and Olaparib Combination in Patients with Metastatic Pancreatic Ductal Adenocarcinoma without BRCA Mutation

por Kim, Joseph W., Cardin, Dana B., Vaishampayan, Ulka N., Kato, Shumei, Grossman, Steven R., Glazer, Peter M., Shyr, Yu, Ivy, S. Percy, LoRusso, Patricia M.
Publicado 2021

Coordinate transcriptional regulation of ErbB2/3 by C-terminal binding protein 2 signals sensitivity to ErbB2 inhibition in pancreatic adenocarcinoma

por Chougoni, Kranthi Kumar, Park, Haemin, Damle, Priyadarshan K., Mason, Travis, Cheng, Bo, Dcona, Martin M., Szomju, Barbara, Dozmorov, Mikhail G., Idowu, Michael O., Grossman, Steven R.
Publicado 2023

Transforming activity and therapeutic targeting of C-terminal Binding Protein 2 in Apc mutated neoplasia

por Sumner, Evan T., Chawla, Ayesha T., Cororaton, Agnes D., Koblinski, Jennifer, Kovi, Ramesh C., Love, Ian M., Szomju, Barbara B., Korwar, Sudha, Ellis, Keith C., Grossman, Steven R.
Publicado 2017

p53-inducible SESTRINs might play opposite roles in the regulation of early and late stages of lung carcinogenesis

por Ding, Boxiao, Haidurov, Alexander, Chawla, Ayesha, Parmigiani, Anita, van de Kamp, Gerarda, Dalina, Alexandra, Yuan, Fang, Lee, Jun Hee, Chumakov, Peter M., Grossman, Steven R., Budanov, Andrei V.
Publicado 2019

The oncogenicity of tumor-derived mutant p53 is enhanced by the recruitment of PLK3

por Vaughan, Catherine A., Singh, Shilpa, Subler, Mark A., Windle, Jolene J., Inoue, Kazushi, Fry, Elizabeth A., Pillappa, Raghavendra, Grossman, Steven R., Windle, Brad, Andrew Yeudall, W., Deb, Swati Palit, Deb, Sumitra
Publicado 2021

CtBP—a targetable dependency for tumor-initiating cell activity and metastasis in pancreatic adenocarcinoma

por Chawla, Ayesha T., Chougoni, Kranthi Kumar, Joshi, Prashant J., Cororaton, Agnes D., Memari, Patrick, Stansfield, John C., Park, Haemin, Seth, Rashmi, Szomju, Barbara, Sima, Adam P., Idowu, Michael O., Ellis, Keith C., Grossman, Steven R.
Publicado 2019

Bcl-xL is translocated to the nucleus via CtBP2 to epigenetically promote metastasis

por Zhang, Tiantian, Li, Sha, Tan, Yingcai Adrian, Na, Joseph HyungJoon, Chen, Zhengming, Damle, Priyadarshan, Chen, Xiang, Choi, Soyoung, Mishra, Bikash, Wang, Dunrui, Grossman, Steven R., Jiang, Xuejun, Li, Yi, Chen, Yao-Tseng, Xiang, Jenny Z., Du, Yi-Chieh Nancy
Publicado 2023