The role of 'omics' in the quest to eliminate human filariasis

por Lustigman, Sara, Grote, Alexandra, Ghedin, Elodie
Publicado 2017

CRISPR-mediated Transfection of Brugia malayi

por Liu, Canhui, Grote, Alexandra, Ghedin, Elodie, Unnasch, Thomas R.
Publicado 2020

Defining Brugia malayi and Wolbachia symbiosis by stage-specific dual RNA-seq

por Grote, Alexandra, Voronin, Denis, Ding, Tao, Twaddle, Alan, Unnasch, Thomas R., Lustigman, Sara, Ghedin, Elodie
Publicado 2017

Cysteine proteases during larval migration and development of helminths in their final host

por Grote, Alexandra, Caffrey, Conor R., Rebello, Karina M., Smith, David, Dalton, John P., Lustigman, Sara
Publicado 2018

Pyruvate produced by Brugia spp. via glycolysis is essential for maintaining the mutualistic association between the parasite and its endosymbiont, Wolbachia

por Voronin, Denis, Schnall, Emily, Grote, Alexandra, Jawahar, Shabnam, Ali, Waleed, Unnasch, Thomas R., Ghedin, Elodie, Lustigman, Sara
Publicado 2019

Modeling the metabolic interplay between a parasitic worm and its bacterial endosymbiont allows the identification of novel drug targets

por Curran, David M, Grote, Alexandra, Nursimulu, Nirvana, Geber, Adam, Voronin, Dennis, Jones, Drew R, Ghedin, Elodie, Parkinson, John
Publicado 2020

Prediction pipeline for discovery of regulatory motifs associated with Brugia malayi molting

por Grote, Alexandra, Li, Yichao, Liu, Canhui, Voronin, Denis, Geber, Adam, Lustigman, Sara, Unnasch, Thomas R., Welch, Lonnie, Ghedin, Elodie
Publicado 2020

Bacterial Filamentation Drives Colony Chirality

por Aranda-Díaz, Andrés, Rodrigues, Cecilia, Grote, Alexandra, Sun, Jiawei, Schreck, Carl, Hallatschek, Oskar, Souslov, Anton, Möbius, Wolfram, Huang, Kerwyn Casey
Publicado 2021

Modulating the evolutionary trajectory of tolerance using antibiotics with different metabolic dependencies

por Zheng, Erica J., Andrews, Ian W., Grote, Alexandra T., Manson, Abigail L., Alcantar, Miguel A., Earl, Ashlee M., Collins, James J.
Publicado 2022

A Meta-Analysis of Wolbachia Transcriptomics Reveals a Stage-Specific Wolbachia Transcriptional Response Shared Across Different Hosts

por Chung, Matthew, Basting, Preston J., Patkus, Rayanna S., Grote, Alexandra, Luck, Ashley N., Ghedin, Elodie, Slatko, Barton E., Michalski, Michelle, Foster, Jeremy M., Bergman, Casey M., Hotopp, Julie C. Dunning
Publicado 2020

StrainGE: a toolkit to track and characterize low-abundance strains in complex microbial communities

por van Dijk, Lucas R., Walker, Bruce J., Straub, Timothy J., Worby, Colin J., Grote, Alexandra, Schreiber, Henry L., Anyansi, Christine, Pickering, Amy J., Hultgren, Scott J., Manson, Abigail L., Abeel, Thomas, Earl, Ashlee M.
Publicado 2022

Stage-Specific Transcriptome and Proteome Analyses of the Filarial Parasite Onchocerca volvulus and Its Wolbachia Endosymbiont

por Bennuru, Sasisekhar, Cotton, James A., Ribeiro, Jose M. C., Grote, Alexandra, Harsha, Bhavana, Holroyd, Nancy, Mhashilkar, Amruta, Molina, Douglas M., Randall, Arlo Z., Shandling, Adam D., Unnasch, Thomas R., Ghedin, Elodie, Berriman, Matthew, Lustigman, Sara, Nutman, Thomas B.
Publicado 2016

Nearly Complete Genome Sequence of Brugia malayi Strain FR3

por Tracey, Alan, Foster, Jeremy M., Paulini, Michael, Grote, Alexandra, Mattick, John, Tsai, Yu-Chih, Chung, Matthew, Cotton, James A., Clark, Tyson A., Geber, Adam, Holroyd, Nancy, Korlach, Jonas, Libro, Silvia, Lustigman, Sara, Michalski, Michelle L., Rogers, Matthew B., Twaddle, Alan, Dunning Hotopp, Julie C., Berriman, Matthew, Ghedin, Elodie
Publicado 2020

Sex chromosome evolution in parasitic nematodes of humans

por Foster, Jeremy M., Grote, Alexandra, Mattick, John, Tracey, Alan, Tsai, Yu-Chih, Chung, Matthew, Cotton, James A., Clark, Tyson A., Geber, Adam, Holroyd, Nancy, Korlach, Jonas, Li, Yichao, Libro, Silvia, Lustigman, Sara, Michalski, Michelle L., Paulini, Michael, Rogers, Matthew B., Teigen, Laura, Twaddle, Alan, Welch, Lonnie, Berriman, Matthew, Dunning Hotopp, Julie C., Ghedin, Elodie
Publicado 2020

The genome of Onchocerca volvulus, agent of river blindness

por Cotton, James A., Bennuru, Sasisekhar, Grote, Alexandra, Harsha, Bhavana, Tracey, Alan, Beech, Robin, Doyle, Stephen R., Dunn, Matthew, Dunning Hotopp, Julie C., Holroyd, Nancy, Kikuchi, Taisei, Lambert, Olivia, Mhashilkar, Amruta, Mutowo, Prudence, Nursimulu, Nirvana, Ribeiro, Jose M. C., Rogers, Matthew B., Stanley, Eleanor, Swapna, Lakshmipuram S., Tsai, Isheng J., Unnasch, Thomas R., Voronin, Denis, Parkinson, John, Nutman, Thomas B., Ghedin, Elodie, Berriman, Matthew, Lustigman, Sara
Publicado 2016