Phosphorylation of eIF4E promotes EMT and metastasis via translational control of SNAIL and MMP-3

por Robichaud, Nathaniel, del Rincon, Sonia V., Huor, Bonnie, Alain, Tommy, Petruccelli, Andy, Hearnden, Jaclyn, Goncalves, Christophe, Grotegut, Stefan, Spruck, Charles H., Furic, Luc, Larsson, Ola, Miller, Wilson H., Sonenberg, Nahum
Publicado 2014

Development of a Robust High-Throughput Screening Platform for Inhibitors of the Striatal-Enriched Tyrosine Phosphatase (STEP)

por Lambert, Lester J, Grotegut, Stefan, Celeridad, Maria, Gosalia, Palak, Backer, Laurent JS De, Bobkov, Andrey A, Salaniwal, Sumeet, Chung, Thomas DY, Zeng, Fu-Yue, Pass, Ian, Lombroso, Paul J, Cosford, Nicholas DP, Tautz, Lutz
Publicado 2021

Inhibition of coronavirus HCoV-OC43 by targeting the eIF4F complex

por Feng, Yongmei, Grotegut, Stefan, Jovanovic, Predrag, Gandin, Valentina, Olson, Steven H., Murad, Rabi, Beall, Anne, Colayco, Sharon, De-Jesus, Paul, Chanda, Sumit, English, Brian P., Singer, Robert H., Jackson, Michael, Topisirovic, Ivan, Ronai, Ze’ev A.
Publicado 2022

Discovery of novel furanylbenzamide inhibitors that target oncogenic tyrosine phosphatase SHP2 in leukemia cells

por Raveendra-Panickar, Dhanya, Finlay, Darren, Layng, Fabiana Izidro, Lambert, Lester J., Celeridad, Maria, Zhao, Ming, Barbosa, Karina, De Backer, Laurent J.S., Kwong, Elizabeth, Gosalia, Palak, Rodiles, Socorro, Holleran, John, Ardecky, Robert, Grotegut, Stefan, Olson, Steven, Hutchinson, John H., Pasquale, Elena B., Vuori, Kristiina, Deshpande, Aniruddha J., Cosford, Nicholas D.P., Tautz, Lutz
Publicado 2021

CDK-mediated activation of the SCF(FBXO28) ubiquitin ligase promotes MYC-driven transcription and tumourigenesis and predicts poor survival in breast cancer

por Cepeda, Diana, Ng, Hwee-Fang, Sharifi, Hamid Reza, Mahmoudi, Salah, Cerrato, Vanessa Soto, Fredlund, Erik, Magnusson, Kristina, Nilsson, Helén, Malyukova, Alena, Rantala, Juha, Klevebring, Daniel, Viñals, Francesc, Bhaskaran, Nimesh, Zakaria, Siti Mariam, Rahmanto, Aldwin Suryo, Grotegut, Stefan, Nielsen, Michael Lund, Szigyarto, Cristina Al-Khalili, Sun, Dahui, Lerner, Mikael, Navani, Sanjay, Widschwendter, Martin, Uhlén, Mathias, Jirström, Karin, Pontén, Fredrik, Wohlschlegel, James, Grandér, Dan, Spruck, Charles, Larsson, Lars-Gunnar, Sangfelt, Olle
Publicado 2013