Identification of Novel Substrates for cGMP Dependent Protein Kinase (PKG) through Kinase Activity Profiling to Understand Its Putative Role in Inherited Retinal Degeneration

por Roy, Akanksha, Groten, John, Marigo, Valeria, Tomar, Tushar, Hilhorst, Riet
Publicado 2021

Kinase activity profiling identifies putative downstream targets of cGMP/PKG signaling in inherited retinal neurodegeneration

por Roy, Akanksha, Tolone, Arianna, Hilhorst, Riet, Groten, John, Tomar, Tushar, Paquet-Durand, François
Publicado 2022

International issues on human health effects of exposure to chemical mixtures.

por Feron, Victor J, Cassee, Flemming R, Groten, John P, van Vliet, Petronella W, van Zorge, Job A
Publicado 2002

The PKG Inhibitor CN238 Affords Functional Protection of Photoreceptors and Ganglion Cells against Retinal Degeneration

por Tolone, Arianna, Haq, Wadood, Fachinger, Alexandra, Roy, Akanksha, Kesh, Sandeep, Rentsch, Andreas, Wucherpfennig, Sophie, Zhu, Yu, Groten, John, Schwede, Frank, Tomar, Tushar, Herberg, Friedrich W., Nache, Vasilica, Paquet-Durand, François
Publicado 2023

Meeting Report: Validation of Toxicogenomics-Based Test Systems: ECVAM–ICCVAM/NICEATM Considerations for Regulatory Use

por Corvi, Raffaella, Ahr, Hans-Jürgen, Albertini, Silvio, Blakey, David H., Clerici, Libero, Coecke, Sandra, Douglas, George R., Gribaldo, Laura, Groten, John P., Haase, Bernd, Hamernik, Karen, Hartung, Thomas, Inoue, Tohru, Indans, Ian, Maurici, Daniela, Orphanides, George, Rembges, Diana, Sansone, Susanna-Assunta, Snape, Jason R., Toda, Eisaku, Tong, Weida, van Delft, Joost H., Weis, Brenda, Schechtman, Leonard M.
Publicado 2006

Blood-based kinase activity profiling: a potential predictor of response to immune checkpoint inhibition in metastatic cancer

por Hurkmans, Daan P, Verdegaal, Els M E, Hogan, Sabrina A, de Wijn, Rik, Hovestad, Lies, van den Heuvel, Dianne M A, Ruijtenbeek, Rob, Welters, Marij J P, van Brakel, Mandy, Basak, Edwin A, Pinedo, Herbert M, Lamers, Cor H J, van de Werken, Harmen J G, Groten, John P, Debets, Reno, Levesque, Mitchell P, Dummer, Reinhard, Kapiteijn, Ellen, Mathijssen, Ron H J, Aerts, Joachim G J V, van der Burg, Sjoerd H
Publicado 2020