Editorial: Advancements in computational studies of drug toxicity

por Flynn, Noah R., Miller, Grover P., Swamidass, S. Joshua
Publicado 2023

Carcinogenicity of 2-Naphthylhydroxylamine and 2-Naphthylamine

por Boyland, E., Dukes, C. E., Grover, P. L.
Publicado 1963

Modeling Epoxidation of Drug-like Molecules with a Deep Machine Learning Network

por Hughes, Tyler B., Miller, Grover P., Swamidass, S. Joshua
Publicado 2015

Tumour-initiating activities on mouse skin of dihydrodiols derived from benzo[a]pyrene.

por Chouroulinkov, I., Gentil, A., Grover, P. L., Sims, P.
Publicado 1976

Comparison of mutagenesis and malignant transformation by dihydrodiols from benz[a]anthracene and 7,12-dimethylbenz[a]anthracene.

por Marquardt, H., Baker, S., Tierney, B., Grover, P. L., Sims, P.
Publicado 1979

The carcinogenicity of polycyclic hydrocarbon epoxides in newborn mice.

por Grover, P. L., Sims, P., Mitchley, B. C., Roe, F. J.
Publicado 1975

Biological activities of dihydrodiols derived from two polycyclic hydrocarbons in rodent test systems.

por Chouroulinkov, I., Gentil, A., Tierney, B., Grover, P. L., Sims, P.
Publicado 1979

Modeling Reactivity to Biological Macromolecules with a Deep Multitask Network

por Hughes, Tyler B., Dang, Na Le, Miller, Grover P., Swamidass, S. Joshua
Publicado 2016

Hydrocarbon-deoxyribonucleoside products formed by the binding of derivatives of 7-methylbenz(A)anthracene to DNA.

por Baird, W. M., Dipple, A., Grover, P. L., Sims, P., Brookes, P.
Publicado 1973

The Induction of Renal Tumours by Feeding Lead Acetate to Rats

por Boyland, E., Dukes, C. E., Grover, P. L., Mitchley, B. C. V.
Publicado 1962

Further Experiments on Implantation of Materials into the Urinary Bladder of Mice

por Boyland, E., Busby, E. R., Dukes, C. E., Grover, P. L., Manson, D.
Publicado 1964

MUC1 induces drug resistance in pancreatic cancer cells via upregulation of multidrug resistance genes

por Nath, S, Daneshvar, K, Roy, L D, Grover, P, Kidiyoor, A, Mosley, L, Sahraei, M, Mukherjee, P
Publicado 2013

Machine learning liver-injuring drug interactions with non-steroidal anti-inflammatory drugs (NSAIDs) from a retrospective electronic health record (EHR) cohort

por Datta, Arghya, Flynn, Noah R., Barnette, Dustyn A., Woeltje, Keith F., Miller, Grover P., Swamidass, S. Joshua
Publicado 2021

A Further Study of Bladder Implantation in the Mouse as a means of Detecting Carcinogenic Activity: Use of Crushed Paraffin Wax or Stearic Acid as the Vehicle

por Bonser, Georgiana M., Boyland, E., Busby, E. R., Clayson, D. B., Grover, P. L., Jull, J. W.
Publicado 1963

Significance of Competing Metabolic Pathways for 5F-APINACA Based on Quantitative Kinetics

por Pinson, Anna O., Pouncey, Dakota L., Schleiff, Mary A., Fantegrossi, William E., Prather, Paul L., Radominska-Pandya, Anna, Boysen, Gunnar, Miller, Grover P.
Publicado 2020

Discovery of Novel Reductive Elimination Pathway for 10-Hydroxywarfarin

por Pouncey, Dakota L., Barnette, Dustyn A., Sinnott, Riley W., Phillips, Sarah J., Flynn, Noah R., Hendrickson, Howard P., Swamidass, S. Joshua, Miller, Grover P.
Publicado 2022

Significance of Multiple Bioactivation Pathways for Meclofenamate as Revealed through Modeling and Reaction Kinetics

por Schleiff, Mary Alexandra, Flynn, Noah R., Payakachat, Sasin, Schleiff, Benjamin Mark, Pinson, Anna O., Province, Dennis W., Swamidass, S. Joshua, Boysen, Gunnar, Miller, Grover P.
Publicado 2021

Bioactivation of Isoxazole-Containing Bromodomain and Extra-Terminal Domain (BET) Inhibitors

por Flynn, Noah R., Ward, Michael D., Schleiff, Mary A., Laurin, Corentine M. C., Farmer, Rohit, Conway, Stuart J., Boysen, Gunnar, Swamidass, S. Joshua, Miller, Grover P.
Publicado 2021

Microsurgery for intracranial aneurysms: A qualitative survey on technical challenges and technological solutions

por Muirhead, W. R., Layard Horsfall, H., Khan, D. Z., Koh, C., Grover, P. J., Toma, A. K., Castanho, P., Stoyanov, D., Marcus, H. J., Murphy, M.
Publicado 2022

Similar 5F-APINACA Metabolism between CD-1 Mouse and Human Liver Microsomes Involves Different P450 Cytochromes

por Crosby, Samantha V., Ahmed, Izzeldin Y., Osborn, Laura R., Wang, Zeyuan, Schleiff, Mary A., Fantegrossi, William E., Nagar, Swati, Prather, Paul L., Boysen, Gunnar, Miller, Grover P.
Publicado 2022