Bromodomain Inhibitors as Therapeutics for Herpesvirus-Related Disease: All BETs Are Off?

por Groves, Ian J., Sinclair, John H., Wills, Mark R.
Publicado 2020

Chromatin control of human cytomegalovirus infection

por Matthews, Stephen M., Groves, Ian J., O'Connor, Christine M.
Publicado 2023

Depletion of polycistronic transcripts using short interfering RNAs: cDNA synthesis method affects levels of non-targeted genes determined by quantitative PCR

por Hanning, Jennifer E, Groves, Ian J, Pett, Mark R, Coleman, Nicholas
Publicado 2013

Virus transcript levels and cell growth rates after naturally occurring HPV16 integration events in basal cervical keratinocytes

por Scarpini, Cinzia G, Groves, Ian J, Pett, Mark R, Ward, Dawn, Coleman, Nicholas
Publicado 2014

Identification of host transcriptional networks showing concentration-dependent regulation by HPV16 E6 and E7 proteins in basal cervical squamous epithelial cells

por Smith, Stephen P., Scarpini, Cinzia G., Groves, Ian J., Odle, Richard I., Coleman, Nicholas
Publicado 2016

Human cytomegalovirus major immediate early transcripts arise predominantly from the canonical major immediate early promoter in reactivating progenitor-derived dendritic cells

por Mason, Rebecca, Groves, Ian J., Wills, Mark R., Sinclair, John H., Reeves, Matthew B.
Publicado 2020

Extensive Co-Operation between the Epstein-Barr Virus EBNA3 Proteins in the Manipulation of Host Gene Expression and Epigenetic Chromatin Modification

por White, Robert E., Groves, Ian J., Turro, Ernest, Yee, Jade, Kremmer, Elisabeth, Allday, Martin J.
Publicado 2010

Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome

por Szymula, Agnieszka, Palermo, Richard D., Bayoumy, Amr, Groves, Ian J., Ba abdullah, Mohammed, Holder, Beth, White, Robert E.
Publicado 2018

Correction: Epstein-Barr virus nuclear antigen EBNA-LP is essential for transforming naïve B cells, and facilitates recruitment of transcription factors to the viral genome

por Szymula, Agnieszka, Palermo, Richard D., Bayoumy, Amr, Groves, Ian J., Ba abdullah, Mohammed, Holder, Beth, White, Robert E.
Publicado 2019

A BMPR2/YY1 Signaling Axis Is Required for Human Cytomegalovirus Latency in Undifferentiated Myeloid Cells

por Poole, Emma, Carlan da Silva, Maria Cristina, Huang, Chris, Perera, Marianne, Jackson, Sarah, Groves, Ian J., Wills, Mark, Rana, Amer, Sinclair, John
Publicado 2021

Bromodomain proteins regulate human cytomegalovirus latency and reactivation allowing epigenetic therapeutic intervention

por Groves, Ian J., Jackson, Sarah E., Poole, Emma L., Nachshon, Aharon, Rozman, Batsheva, Schwartz, Michal, Prinjha, Rab K., Tough, David F., Sinclair, John H., Wills, Mark R.
Publicado 2021

Targeting the latent human cytomegalovirus reservoir for T-cell-mediated killing with virus-specific nanobodies

por De Groof, Timo W. M., Elder, Elizabeth G., Lim, Eleanor Y., Heukers, Raimond, Bergkamp, Nick D., Groves, Ian J., Wills, Mark, Sinclair, John H., Smit, Martine J.
Publicado 2021

Short- and long-range cis interactions between integrated HPV genomes and cellular chromatin dysregulate host gene expression in early cervical carcinogenesis

por Groves, Ian J., Drane, Emma L. A., Michalski, Marco, Monahan, Jack M., Scarpini, Cinzia G., Smith, Stephen P., Bussotti, Giovanni, Várnai, Csilla, Schoenfelder, Stefan, Fraser, Peter, Enright, Anton J., Coleman, Nicholas
Publicado 2021

Disruption of CTCF-YY1–dependent looping of the human papillomavirus genome activates differentiation-induced viral oncogene transcription

por Pentland, Ieisha, Campos-León, Karen, Cotic, Marius, Davies, Kelli-Jo, Wood, C. David, Groves, Ian J., Burley, Megan, Coleman, Nicholas, Stockton, Joanne D., Noyvert, Boris, Beggs, Andrew D., West, Michelle J., Roberts, Sally, Parish, Joanna L.
Publicado 2018

Killer cell proteases can target viral immediate-early proteins to control human cytomegalovirus infection in a noncytotoxic manner

por Shan, Liling, Li, Shuang, Meeldijk, Jan, Blijenberg, Bernadet, Hendriks, Astrid, van Boxtel, Karlijn J. W. M., van den Berg, Sara P. H., Groves, Ian J., Potts, Martin, Svrlanska, Adriana, Stamminger, Thomas, Wills, Mark R., Bovenschen, Niels
Publicado 2020

Latent Cytomegalovirus-Driven Recruitment of Activated CD4+ T Cells Promotes Virus Reactivation

por Jackson, Sarah E., Chen, Kevin C., Groves, Ian J., Sedikides, George X., Gandhi, Amar, Houldcroft, Charlotte J., Poole, Emma L., Montanuy, Inmaculada, Mason, Gavin M., Okecha, Georgina, Reeves, Matthew B., Sinclair, John H., Wills, Mark R.
Publicado 2021

Cytomegalovirus US28 regulates cellular EphA2 to maintain viral latency

por Wass, Amanda B., Krishna, Benjamin A., Herring, Laura E., Gilbert, Thomas S. K., Nukui, Masatoshi, Groves, Ian J., Dooley, Abigail L., Kulp, Katherine H., Matthews, Stephen M., Rotroff, Daniel M., Graves, Lee M., O’Connor, Christine M.
Publicado 2022