A small molecule drug promoting miRNA processing induces alternative splicing of MdmX transcript and rescues p53 activity in human cancer cells overexpressing MdmX protein

por Valianatos, Georgios, Valcikova, Barbora, Growkova, Katerina, Verlande, Amandine, Mlcochova, Jitka, Radova, Lenka, Stetkova, Monika, Vyhnakova, Michaela, Slaby, Ondrej, Uldrijan, Stjepan
Publicado 2017

Active site alanine mutations convert deubiquitinases into high‐affinity ubiquitin‐binding proteins

por Morrow, Marie E, Morgan, Michael T, Clerici, Marcello, Growkova, Katerina, Yan, Ming, Komander, David, Sixma, Titia K, Simicek, Michal, Wolberger, Cynthia
Publicado 2018

Newly designed 11-gene panel reveals first case of hereditary amyloidosis captured by massive parallel sequencing

por Chyra Kufova, Zuzana, Sevcikova, Tereza, Januska, Jaroslav, Vojta, Petr, Boday, Arpad, Vanickova, Pavla, Filipova, Jana, Growkova, Katerina, Jelinek, Tomas, Hajduch, Marian, Hajek, Roman
Publicado 2018

CDK9 activity is critical for maintaining MDM4 overexpression in tumor cells

por Štětková, Monika, Growková, Kateřina, Fojtík, Petr, Valčíková, Barbora, Palušová, Veronika, Verlande, Amandine, Jorda, Radek, Kryštof, Vladimír, Hejret, Václav, Alexiou, Panagiotis, Rotrekl, Vladimír, Uldrijan, Stjepan
Publicado 2020

Mutation landscape of multiple myeloma measurable residual disease: identification of targets for precision medicine

por Zátopková, Martina, Ševčíková, Tereza, Fanfani, Viola, Chyra, Zuzana, Říhová, Lucie, Bezděková, Renata, Žihala, David, Growková, Kateřina, Filipová, Jana, Černá, Lucie, Broskevičova, Lucie, Kryukov, Fedor, Minařík, Jiří, Smejkalová, Jana, Maisnar, Vladimír, Harvanová, Ĺubica, Pour, Luděk, Jungova, Alexandra, Popková, Tereza, Bago, Juli Rodriguez, Anilkumar Sithara, Anjana, Hrdinka, Matouš, Jelínek, Tomáš, Šimíček, Michal, Stracquadanio, Giovanni, Hájek, Roman
Publicado 2022

Heterogenous mutation spectrum and deregulated cellular pathways in aberrant plasma cells underline molecular pathology of light-chain amyloidosis

por Chyra, Zuzana, Sevcikova, Tereza, Vojta, Petr, Puterova, Janka, Brozova, Lucie, Growkova, Katerina, Filipova, Jana, Zatopkova, Martina, Grosicki, Sebastian, Barchnicka, Agnieszka, Wiktor-Jedrzejczak, Wieslaw, Waszczuk-Gajda, Anna, Jungova, Alexandra, Mikulasova, Aneta, Hajduch, Marian, Mokrejs, Martin, Pour, Ludek, Stork, Martin, Harvanova, Lubica, Mistrik, Martin, Mikala, Gabor, Robak, Pawel, Czyz, Anna, Debski, Jakub, Usnarska-Zubkiewicz, Lidia, Jurczyszyn, Artur, Stejskal, Lukas, Morgan, Gareth, Kryukov, Fedor, Budinska, Eva, Simicek, Michal, Jelinek, Tomas, Hrdinka, Matous, Hajek, Roman
Publicado 2020