Frozen and freeze‐dried solvent/detergent treated plasma: Two different pharmaceutical formulations with comparable quality

por Heger, Andrea, Gruber, Gerhard
Publicado 2022

Re-Understanding the Mechanisms of Action of the Anti-Mycobacterial Drug Bedaquiline

por Sarathy, Jickky Palmae, Gruber, Gerhard, Dick, Thomas
Publicado 2019

Binding properties of the anti-TB drugs bedaquiline and TBAJ-876 to a mycobacterial F-ATP synthase

por Krah, Alexander, Grüber, Gerhard, Bond, Peter J.
Publicado 2022

Bedaquiline Targets the ε Subunit of Mycobacterial F-ATP Synthase

por Kundu, Subhashri, Biukovic, Goran, Grüber, Gerhard, Dick, Thomas
Publicado 2016

Molecular mechanism of the Escherichia coli AhpC in the function of a chaperone under heat-shock conditions

por Kamariah, Neelagandan, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
Publicado 2018

Low-resolution structure of the soluble domain GPAA1 (yGPAA1(70–247)) of the glycosylphosphatidylinositol transamidase subunit GPAA1 from Saccharomyces cerevisiae

por Saw, Wuan Geok, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
Publicado 2013

Transamidase subunit GAA1/GPAA1 is a M28 family metallo-peptide-synthetase that catalyzes the peptide bond formation between the substrate protein’s omega-site and the GPI lipid an...

por Eisenhaber, Birgit, Eisenhaber, Stephan, Kwang, Toh Yew, Grüber, Gerhard, Eisenhaber, Frank
Publicado 2014

Transition steps in peroxide reduction and a molecular switch for peroxide robustness of prokaryotic peroxiredoxins

por Kamariah, Neelagandan, Sek, Mun Foong, Eisenhaber, Birgit, Eisenhaber, Frank, Grüber, Gerhard
Publicado 2016

Low Resolution Solution Structure of HAMLET and the Importance of Its Alpha-Domains in Tumoricidal Activity

por Ho CS, James, Rydstrom, Anna, Manimekalai, Malathy Sony Subramanian, Svanborg, Catharina, Grüber, Gerhard
Publicado 2012

Crystallographic structure of the turbine C-ring from spinach chloroplast F-ATP synthase

por Balakrishna, Asha Manikkoth, Seelert, Holger, Marx, Sven-Hendric, Dencher, Norbert A., Grüber, Gerhard
Publicado 2014

Targeting Mycobacterial F-ATP Synthase C-Terminal α Subunit Interaction Motif on Rotary Subunit γ

por Harikishore, Amaravadhi, Wong, Chui-Fann, Ragunathan, Priya, Litty, Dennis, Müller, Volker, Grüber, Gerhard
Publicado 2021

TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug’s Uncoupler Activity

por Sarathy, Jickky Palmae, Ragunathan, Priya, Cooper, Christopher B., Upton, Anna M., Grüber, Gerhard, Dick, Thomas
Publicado 2020

Structural Determination of Functional Units of the Nucleotide Binding Domain (NBD94) of the Reticulocyte Binding Protein Py235 of Plasmodium yoelii

por Grüber, Ardina, Manimekalai, Malathy S. S., Balakrishna, Asha M., Hunke, Cornelia, Jeyakanthan, Jeyaraman, Preiser, Peter R., Grüber, Gerhard
Publicado 2010

TBAJ-876 Retains Bedaquiline’s Activity against Subunits c and ε of Mycobacterium tuberculosis F-ATP Synthase

por Sarathy, Jickky Palmae, Ragunathan, Priya, Shin, Joon, Cooper, Christopher B., Upton, Anna M., Grüber, Gerhard, Dick, Thomas
Publicado 2019

AhpC of the mycobacterial antioxidant defense system and its interaction with its reducing partner Thioredoxin-C

por Wong, Chui Fann, Shin, Joon, Subramanian Manimekalai, Malathy Sony, Saw, Wuan Geok, Yin, Zhan, Bhushan, Shashi, Kumar, Arvind, Ragunathan, Priya, Grüber, Gerhard
Publicado 2017

Abundant neuroprotective chaperone Lipocalin-type prostaglandin D synthase (L-PGDS) disassembles the Amyloid-β fibrils

por Kannaian, Bhuvaneswari, Sharma, Bhargy, Phillips, Margaret, Chowdhury, Anup, Manimekalai, Malathy S. S., Adav, Sunil S., Ng, Justin T. Y., Kumar, Ambrish, Lim, Sierin, Mu, Yuguang, Sze, Siu K., Grüber, Gerhard, Pervushin, Konstantin
Publicado 2019

Structural transition in Bcl-xL and its potential association with mitochondrial calcium ion transport

por Rajan, Sreekanth, Choi, Minjoo, Nguyen, Quoc Toan, Ye, Hong, Liu, Wei, Toh, Hui Ting, Kang, CongBao, Kamariah, Neelagandan, Li, Chi, Huang, Huiya, White, Carl, Baek, Kwanghee, Grüber, Gerhard, Yoon, Ho Sup
Publicado 2015

Pyrazinamide triggers degradation of its target aspartate decarboxylase

por Gopal, Pooja, Sarathy, Jickky Palmae, Yee, Michelle, Ragunathan, Priya, Shin, Joon, Bhushan, Shashi, Zhu, Junhao, Akopian, Tatos, Kandror, Olga, Lim, Teck Kwang, Gengenbacher, Martin, Lin, Qingsong, Rubin, Eric J., Grüber, Gerhard, Dick, Thomas
Publicado 2020

Disrupting coupling within mycobacterial F-ATP synthases subunit ε causes dysregulated energy production and cell wall biosynthesis

por Saw, Wuan-Geok, Wu, Mu-Lu, Ragunathan, Priya, Biuković, Goran, Lau, Aik-Meng, Shin, Joon, Harikishore, Amaravadhi, Cheung, Chen-Yi, Hards, Kiel, Sarathy, Jickky Palmae, Bates, Roderick W., Cook, Gregory M., Dick, Thomas, Grüber, Gerhard
Publicado 2019

Targeting the Mycobacterium ulcerans cytochrome bc(1):aa(3) for the treatment of Buruli ulcer

por Scherr, Nicole, Bieri, Raphael, Thomas, Sangeeta S., Chauffour, Aurélie, Kalia, Nitin Pal, Schneide, Paul, Ruf, Marie-Thérèse, Lamelas, Araceli, Manimekalai, Malathy S. S., Grüber, Gerhard, Ishii, Norihisa, Suzuki, Koichi, Tanner, Marcel, Moraski, Garrett C., Miller, Marvin J., Witschel, Matthias, Jarlier, Vincent, Pluschke, Gerd, Pethe, Kevin
Publicado 2018