Chromatin accessibility associates with protein-RNA correlation in human cancer

por Sanghi, Akshay, Gruber, Joshua J., Metwally, Ahmed, Jiang, Lihua, Reynolds, Warren, Sunwoo, John, Orloff, Lisa, Chang, Howard Y., Kasowski, Maya, Snyder, Michael P.
Publicado 2021

Matrix stiffness induces a tumorigenic phenotype in mammary epithelium through changes in chromatin accessibility

por Stowers, Ryan S., Shcherbina, Anna, Israeli, Johnny, Gruber, Joshua J., Chang, Julie, Nam, Sungmin, Rabiee, Atefeh, Teruel, Mary N., Snyder, Michael P., Kundaje, Anshul, Chaudhuri, Ovijit
Publicado 2019

Disruption of mesoderm formation during cardiac differentiation due to developmental exposure to 13-cis-retinoic acid

por Liu, Qing, Van Bortle, Kevin, Zhang, Yue, Zhao, Ming-Tao, Zhang, Joe Z., Geller, Benjamin S., Gruber, Joshua J., Jiang, Chao, Wu, Joseph C., Snyder, Michael P.
Publicado 2018

Rationally targeted anti-VISTA antibody that blockades the C-C’ loop region can reverse VISTA immune suppression and remodel the immune microenvironment to potently inhibit tumor g...

por Thakkar, Dipti, Paliwal, Shalini, Dharmadhikari, Bhushan, Guan, Siyu, Liu, Lillian, Kar, Shreya, Tulsian, Nikhil K, Gruber, Joshua J, DiMascio, Leah, Paszkiewicz, Konrad H, Ingram, Piers J, D Boyd-Kirkup, Jerome
Publicado 2022

A phase II study of talazoparib monotherapy in patients with wild-type BRCA1 and BRCA2 with a mutation in other homologous recombination genes

por Gruber, Joshua J., Afghahi, Anosheh, Timms, Kirsten, DeWees, Alyssa, Gross, Wyatt, Aushev, Vasily N., Wu, Hsin-Ta, Balcioglu, Mustafa, Sethi, Himanshu, Scott, Danika, Foran, Jessica, McMillan, Alex, Ford, James M., Telli, Melinda L.
Publicado 2022

Imatinib-resistance associated with BCR-ABL upregulation is dependent on HIF-1α-induced metabolic reprogramming

por Zhao, Fangping, Mancuso, Anthony, Bui, Thi V., Tong, Xuemei, Gruber, Joshua J., Swider, Cezary R., Sanchez, Patricia V, Lum, Julian J., Sayed, Nabil, Melo, Junia V., Perl, Alexander E., Carroll, Martin, Tuttle, Stephen W., Thompson, Craig B.
Publicado 2010

Acetate supplementation restores chromatin accessibility and promotes tumor cell differentiation under hypoxia

por Li, Yang, Gruber, Joshua J., Litzenburger, Ulrike M., Zhou, Yiren, Miao, Yu Rebecca, LaGory, Edward L., Li, Albert M., Hu, Zhen, Yip, Michaela, Hart, Lori S., Maris, John M., Chang, Howard Y., Giaccia, Amato J., Ye, Jiangbin
Publicado 2020