Acute Megakaryoblastic Leukemia with Trisomy 21 and Tetrasomy 21 Clones in a Phenotypically Normal Child with Mosaic Trisomy 21

por Won, Eric, Gruber, Tanja A., Tucker, Suzanne, Schiff, Deborah E.
Publicado 2020

DNA Methylation Clusters and Their Relation to Cytogenetic Features in Pediatric AML

por Lamba, Jatinder K., Cao, Xueyuan, Raimondi, Susana, Downing, James, Ribeiro, Raul, Gruber, Tanja A., Rubnitz, Jeffrey, Pounds, Stanley
Publicado 2020

Whole exome sequencing identifies a novel somatic mutation in MMP8 associated with a t(1;22)-acute megakaryoblastic leukemia

por Kim, Yeunhee, Schulz, Vincent P., Satake, Noriko, Gruber, Tanja A., Teixeira, Alexandra M., Halene, Stephanie, Gallagher, Patrick G., Krause, Diane S.
Publicado 2013

A 6-gene leukemic stem cell score identifies high risk pediatric acute myeloid leukemia

por Elsayed, Abdelrahman H., Rafiee, Roya, Cao, Xueyuan, Raimondi, Susana, Downing, James R., Ribeiro, Raul, Fan, Yiping, Gruber, Tanja A., Baker, Sharyn, Klco, Jeffery, Rubnitz, Jeffrey E., Pounds, Stanley, Lamba, Jatinder K.
Publicado 2019

Sensitive GATA1 mutation screening reliably identifies neonates with Down syndrome at risk for myeloid leukemia

por Goemans, Bianca F., Noort, Sanne, Blink, Marjolein, Wang, Yong-Dong, Peters, Susan T. C. J., van Wouwe, Jacobus P., Kaspers, Gertjan, de Haas, Valerie, Kollen, Wouter J., van der Velden, Vincent H. J., Gruber, Tanja A., Zwaan, Christian M.
Publicado 2021

Long-read sequencing unveils IGH-DUX4 translocation into the silenced IGH allele in B-cell acute lymphoblastic leukemia

por Tian, Liqing, Shao, Ying, Nance, Stephanie, Dang, Jinjun, Xu, Beisi, Ma, Xiaotu, Li, Yongjin, Ju, Bensheng, Dong, Li, Newman, Scott, Zhou, Xin, Schreiner, Patrick, Tseng, Elizabeth, Hon, Ting, Ashby, Meredith, Li, Chunliang, Easton, John, Gruber, Tanja A., Zhang, Jinghui
Publicado 2019

Clofarabine treatment of KMT2Ar infantile patients with acute lymphoblastic leukemia in St. Jude Total Therapy Study 16

por Gruber, Tanja A., Pei, Deqing, Choi, John, Cheng, Cheng, Coustan-Smith, Elaine, Campana, Dario, Swanson, Hope D., Pauley, Jennifer L., Inaba, Hiroto, Metzger, Monika L., Rubnitz, Jeffrey E., Ribeiro, Raul C., Raimondi, Susana C., Pui, Ching-Hon, Jeha, Sima
Publicado 2022

A high-throughput screen indicates gemcitabine and JAK inhibitors may be useful for treating pediatric AML

por Drenberg, Christina D., Shelat, Anang, Dang, Jinjun, Cotton, Anitria, Orwick, Shelley J., Li, Mengyu, Jeon, Jae Yoon, Fu, Qiang, Buelow, Daelynn R., Pioso, Marissa, Hu, Shuiying, Inaba, Hiroto, Ribeiro, Raul C., Rubnitz, Jeffrey E., Gruber, Tanja A., Guy, R. Kiplin, Baker, Sharyn D.
Publicado 2019

An unexpected protein interaction promotes drug resistance in leukemia

por Pitre, Aaron, Ge, Yubin, Lin, Wenwei, Wang, Yao, Fukuda, Yu, Temirov, Jamshid, Phillips, Aaron H., Peters, Jennifer L., Fan, Yiping, Ma, Jing, Nourse, Amanda, Sinha, Chandrima, Lin, Hai, Kriwacki, Richard, Downing, James R., Gruber, Tanja A., Centonze, Victoria E., Naren, Anjaparavanda P., Chen, Taosheng, Schuetz, John D.
Publicado 2017

Uncovering the Genomic Landscape in Newly Diagnosed and Relapsed Pediatric Cytogenetically Normal FLT 3‐ITD AML

por Buelow, Daelynn R., Pounds, Stanley B., Wang, Yong‐Dong, Shi, Lei, Li, Yongjin, Finkelstein, David, Shurtleff, Sheila, Neale, Geoffrey, Inaba, Hiroto, Ribeiro, Raul C., Palumbo, Reid, Garrison, Dominique, Orwick, Shelley J., Blachly, James S., Kroll, Karl, Byrd, John C., Gruber, Tanja A., Rubnitz, Jeffrey E., Baker, Sharyn D.
Publicado 2019

Analysis of rare driving events in pediatric acute myeloid leukemia

por Noort, Sanne, van Oosterwijk, Jolieke, Ma, Jing, Garfinkle, Elizabeth A.R., Nance, Stephanie, Walsh, Michael, Song, Guangchun, Reinhardt, Dirk, Pigazzi, Martina, Locatelli, Franco, Hasle, Henrik, Abrahamsson, Jonas, Jarosova, Marie, Kelaidi, Charikleia, Polychronopoulou, Sophia, van den Heuvel-Eibrink, Marry M., Fornerod, Maarten, Gruber, Tanja A., Zwaan, C. Michel
Publicado 2022

Clinical Impact of Minimal Residual Disease in Children with Different Subtypes of Acute Lymphoblastic Leukemia Treated with Response-Adapted Therapy

por Pui, Ching-Hon, Pei, Deqing, Raimondi, Susana C, Coustan-Smith, Elaine, Jeha, Sima, Cheng, Cheng, Bowman, W Paul, Sandlund, John T, Ribeiro, Raul C, Rubnitz, Jeffrey E, Inaba, Hiroto, Gruber, Tanja A, Leung, Wing H, Yang, Jun J, Downing, James R, Evans, William E, Relling, Mary V, Campana, Dario
Publicado 2016

De novo activating mutations drive clonal evolution and enhance clonal fitness in KMT2A-rearranged leukemia

por Hyrenius-Wittsten, Axel, Pilheden, Mattias, Sturesson, Helena, Hansson, Jenny, Walsh, Michael P., Song, Guangchun, Kazi, Julhash U., Liu, Jian, Ramakrishan, Ramprasad, Garcia-Ruiz, Cristian, Nance, Stephanie, Gupta, Pankaj, Zhang, Jinghui, Rönnstrand, Lars, Hultquist, Anne, Downing, James R., Lindkvist-Petersson, Karin, Paulsson, Kajsa, Järås, Marcus, Gruber, Tanja A., Ma, Jing, Hagström-Andersson, Anna K.
Publicado 2018

Comprehensive analysis of dose intensity of acute lymphoblastic leukemia chemotherapy

por Karol, Seth E., Pei, Deqing, Smith, Colton A., Liu, Yiwei, Yang, Wenjian, Kornegay, Nancy M., Panetta, John C., Crews, Kristine R., Cheng, Cheng, Finch, Emily R., Inaba, Hiroto, Metzger, Monika L., Rubnitz, Jeffrey E., Ribeiro, Raul C., Gruber, Tanja A., Yang, Jun J., Evans, William E., Jeha, Sima, Pui, Ching-Hon, Relling, Mary V.
Publicado 2021

Favorable outcome of NUTM1-rearranged infant and pediatric B cell precursor acute lymphoblastic leukemia in a collaborative international study

por Boer, Judith M., Valsecchi, Maria Grazia, Hormann, Femke M., Antić, Željko, Zaliova, Marketa, Schwab, Claire, Cazzaniga, Giovanni, Arfeuille, Chloé, Cavé, Hélène, Attarbaschi, Andishe, Strehl, Sabine, Escherich, Gabriele, Imamura, Toshihiko, Ohki, Kentaro, Grüber, Tanja A., Sutton, Rosemary, Pastorczak, Agata, Lammens, Tim, Lambert, Frédéric, Li, Chi Kong, Carrillo de Santa Pau, Enrique, Hoffmann, Steve, Möricke, Anja, Harrison, Christine J., Den Boer, Monique L., De Lorenzo, Paola, Stam, Ronald W., Bergmann, Anke K., Pieters, Rob
Publicado 2021

Clinical cancer genomic profiling by three-platform sequencing of whole genome, whole exome and transcriptome

por Rusch, Michael, Nakitandwe, Joy, Shurtleff, Sheila, Newman, Scott, Zhang, Zhaojie, Edmonson, Michael N., Parker, Matthew, Jiao, Yuannian, Ma, Xiaotu, Liu, Yanling, Gu, Jiali, Walsh, Michael F., Becksfort, Jared, Thrasher, Andrew, Li, Yongjin, McMurry, James, Hedlund, Erin, Patel, Aman, Easton, John, Yergeau, Donald, Vadodaria, Bhavin, Tatevossian, Ruth G., Raimondi, Susana, Hedges, Dale, Chen, Xiang, Hagiwara, Kohei, McGee, Rose, Robinson, Giles W., Klco, Jeffery M., Gruber, Tanja A., Ellison, David W., Downing, James R, Zhang, Jinghui
Publicado 2018

Integrative Genomic Analysis of Pediatric Myeloid-Related Acute Leukemias Identifies Novel Subtypes and Prognostic Indicators

por Fornerod, Maarten, Ma, Jing, Noort, Sanne, Liu, Yu, Walsh, Michael P., Shi, Lei, Nance, Stephanie, Liu, Yanling, Wang, Yuanyuan, Song, Guangchun, Lamprecht, Tamara, Easton, John, Mulder, Heather L., Yergeau, Donald, Myers, Jacquelyn, Kamens, Jennifer L., Obeng, Esther A., Pigazzi, Martina, Jarosova, Marie, Kelaidi, Charikleia, Polychronopoulou, Sophia, Lamba, Jatinder K., Baker, Sharyn D., Rubnitz, Jeffrey E., Reinhardt, Dirk, van den Heuvel-Eibrink, Marry M., Locatelli, Franco, Hasle, Henrik, Klco, Jeffery M., Downing, James R., Zhang, Jinghui, Pounds, Stanley, Zwaan, C. Michel, Gruber, Tanja A.
Publicado 2021

Author Correction: Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia

por Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.
Publicado 2023

Proteasome inhibition targets the KMT2A transcriptional complex in acute lymphoblastic leukemia

por Kamens, Jennifer L., Nance, Stephanie, Koss, Cary, Xu, Beisi, Cotton, Anitria, Lam, Jeannie W., Garfinkle, Elizabeth A. R., Nallagatla, Pratima, Smith, Amelia M. R., Mitchell, Sharnise, Ma, Jing, Currier, Duane, Wright, William C., Kavdia, Kanisha, Pagala, Vishwajeeth R., Kim, Wonil, Wallace, LaShanale M., Cho, Ji-Hoon, Fan, Yiping, Seth, Aman, Twarog, Nathaniel, Choi, John K., Obeng, Esther A., Hatley, Mark E., Metzger, Monika L., Inaba, Hiroto, Jeha, Sima, Rubnitz, Jeffrey E., Peng, Junmin, Chen, Taosheng, Shelat, Anang A., Guy, R. Kiplin, Gruber, Tanja A.
Publicado 2023

The landscape of somatic mutations in Infant MLL rearranged acute lymphoblastic leukemias

por Andersson, Anna K, Ma, Jing, Wang, Jianmin, Chen, Xiang, Gedman, Amanda Larson, Dang, Jinjun, Nakitandwe, Joy, Holmfeldt, Linda, Parker, Matthew, Easton, John, Huether, Robert, Kriwacki, Richard, Rusch, Michael, Wu, Gang, Li, Yongjin, Mulder, Heather, Raimondi, Susana, Pounds, Stanley, Kang, Guolian, Shi, Lei, Becksfort, Jared, Gupta, Pankaj, Payne-Turner, Debbie, Vadodaria, Bhavin, Boggs, Kristy, Yergeau, Donald, Manne, Jayanthi, Song, Guangchun, Edmonson, Michael, Nagahawatte, Panduka, Wei, Lei, Cheng, Cheng, Pei, Deqing, Sutton, Rosemary, Venn, Nicola C, Chetcuti, Albert, Rush, Amanda, Catchpoole, Daniel, Heldrup, Jesper, Fioretos, Thoas, Lu, Charles, Ding, Li, Pui, Ching-Hon, Shurtleff, Sheila, Mullighan, Charles G, Mardis, Elaine R, Wilson, Richard K, Gruber, Tanja A, Zhang, Jinghui, Downing, James R
Publicado 2015