A critical role of PRDM14 in human primordial germ cell fate revealed by inducible degrons

por Sybirna, Anastasiya, Tang, Walfred W. C., Pierson Smela, Merrick, Dietmann, Sabine, Gruhn, Wolfram H., Brosh, Ran, Surani, M. Azim
Publicado 2020

Metabolic regulation of pluripotency and germ cell fate through α‐ketoglutarate

por Tischler, Julia, Gruhn, Wolfram H, Reid, John, Allgeyer, Edward, Buettner, Florian, Marr, Carsten, Theis, Fabian, Simons, Ben D, Wernisch, Lorenz, Surani, M Azim
Publicado 2018

Sequential enhancer state remodelling defines human germline competence and specification

por Tang, Walfred W.C., Castillo-Venzor, Aracely, Gruhn, Wolfram H., Kobayashi, Toshihiro, Penfold, Christopher A., Morgan, Michael D., Sun, Dawei, Irie, Naoko, Azim Surani, M.
Publicado 2022

Epigenetic resetting in the human germ line entails histone modification remodeling

por Gruhn, Wolfram H., Tang, Walfred W.C., Dietmann, Sabine, Alves-Lopes, João P., Penfold, Christopher A., Wong, Frederick C. K., Ramakrishna, Navin B., Surani, M. Azim
Publicado 2023

Gadd45α modulates aversive learning through post‐transcriptional regulation of memory‐related mRNAs

por Aparisi Rey, Alejandro, Karaulanov, Emil, Sharopov, Salim, Arab, Khelifa, Schäfer, Andrea, Gierl, Mathias, Guggenhuber, Stephan, Brandes, Caroline, Pennella, Luigi, Gruhn, Wolfram H, Jelinek, Ruth, Maul, Christina, Conrad, Andrea, Kilb, Werner, Luhmann, Heiko J, Niehrs, Christof, Lutz, Beat
Publicado 2019

Single-cell roadmap of human gonadal development

por Garcia-Alonso, Luz, Lorenzi, Valentina, Mazzeo, Cecilia Icoresi, Alves-Lopes, João Pedro, Roberts, Kenny, Sancho-Serra, Carmen, Engelbert, Justin, Marečková, Magda, Gruhn, Wolfram H., Botting, Rachel A., Li, Tong, Crespo, Berta, van Dongen, Stijn, Kiselev, Vladimir Yu, Prigmore, Elena, Herbert, Mary, Moffett, Ashley, Chédotal, Alain, Bayraktar, Omer Ali, Surani, Azim, Haniffa, Muzlifah, Vento-Tormo, Roser
Publicado 2022